
Villa holiday rentals in James Island
Find and book unique villas on Airbnb
Top-rated villa rentals in James Island
Guests agree: these villas are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for villa rentals in James Island
Private villa rentals

Seagrove Villa 3A - Luxurious Ocean View! Pool!

Beach Club Villa 32 - Elite Oceanfront! Pool!

Port O' Call B103 - Oceanfront Oasis! Walkout!

Upscale, Private,Breathtaking Views

Seagrove Villa 11C - Extreme Oceanfront! Resort!

New reno, Boho-style "treehouse" at the beach!

Coastal Villa with all the Comforts of Home!

New! Oceanfront with amazing views in popular area
Luxury villa rentals

Ocean 180 | Easily Best Oceanfront View | All New

Beachfront IOP Villa with Outdoor Pool. Remodeled!

Comfy Cool-Pool-River Views-Beautifully Updated

Spacious & Steps to the Beach at Kiawah Island

Amenity Cards+Views+Dogs OK

Close to beach, pool, tennis, golf+Amenity card

Coastal 3BR in Old Village with patio & yard

Beautiful, Golf/Lagoon Views! Pet Friendly!
Villa rentals with a pool

Dog friendly villa on 8th hole of golf course

Mariner's Walk 12E - Modern Oceanfront Villa!

Linkside Court 21 - Community Tennis/Pickleball!

Fairway Dunes 11 - Immaculate Remodel! Pickleball!

Tree top living on Seabrook Island!

Desirable Seagrove Villa- Beachside, Pool Access

Surfside Villa | Oceanfront Luxury | 8 Beach Club

Courtside Dream | Private Condo | Amazing Sunsets
Destinations to explore
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- Rentals with outdoor seating James Island
- Family-friendly rentals James Island
- Rentals with a patio James Island
- Rentals with pools James Island
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- Bed and breakfasts James Island
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- Rentals with a washing machine and dryer James Island
- Townhouse rentals James Island
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- Rentals with an EV charger James Island
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- Waterfront rentals James Island
- House rentals James Island
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- Flat rentals James Island
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- Villa rentals Charleston County
- Villa rentals South Carolina
- Villa rentals United States
- Park Circle
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Bulls Island
- Middleton Place
- James Island County Park
- Waterfront Park
- The Golf Club at Wescott Plantation
- Shem Creek Park
- Harbor Island Beach
- Hampton Park
- Angel Oak Tree
- The Charleston Museum
- Secession Golf Club
- Isle of Palms Beach
- Bull Point Beach
- Morris Island Lighthouse
- Seabrook Island Beach
- Hunting Island Beach
- Charleston Aqua Park
- Gibbes Museum of Art
- Edingsville Beach
- White Point Garden
- Seabrook Beach
- Things to do James Island
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- Food and drink James Island
- Sports activities James Island
- Sightseeing James Island
- Nature and outdoors James Island
- Things to do Charleston County
- Tours Charleston County
- Food and drink Charleston County
- Sports activities Charleston County
- Art and culture Charleston County
- Sightseeing Charleston County
- Nature and outdoors Charleston County
- Things to do South Carolina
- Sports activities South Carolina
- Art and culture South Carolina
- Wellness South Carolina
- Tours South Carolina
- Entertainment South Carolina
- Nature and outdoors South Carolina
- Sightseeing South Carolina
- Food and drink South Carolina
- Things to do United States
- Entertainment United States
- Wellness United States
- Sports activities United States
- Art and culture United States
- Tours United States
- Food and drink United States
- Sightseeing United States
- Nature and outdoors United States