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Apartment holiday rentals in Panama City

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama City

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Top guest favourite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Flat in Panama City
5 out of 5 average rating, 43 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Top guest favourite
A cozy living area with a large window offering a panoramic view of the city lights at night. A comfortable sofa is positioned to face a television, creating a relaxed space. The room's walls are softly illuminated, enhancing the viewing experience.
Flat in Panamá
4.98 out of 5 average rating, 124 reviews

The Spot Panama - Comfy, great view & much more

Ideally located in Panama City Panama 🇵🇦 we're just 15-20 minutes from Tocumen Airport 🛩 . Approximately 10 minutes from Albrook Mall, SoHo Mall, Alta Plaza, Multiplaza and much more! Enjoy easy access to supermarkets and restaurants!. Experience peace of mind with 24/7 security and outstanding facilities: pool, gym, and free parking! More than a stay, it's a chance to shop, unwind, and soak in Panama City views. Don't hesitate- Book instantly or contact us if you have any questions.

Guest favourite
A well-appointed living area is showcased with a light sofa and decorative pillows, arranged on a patterned rug. Expansive floor-to-ceiling windows allow natural light to illuminate the space, offering views of the city. A coffee table and stylish floor lamp complement the inviting atmosphere.
Flat in Panama City
5 out of 5 average rating, 19 reviews

Luxury 2BR w/Ocean Views – 27th Fl, Wanders YOO

The name of the Complex comes from the world-renowned architect and interior designer, Marcel Wanders. He had the idea to accentuate the flora and fauna of Panama and bring a relaxed sensation even though the complex is located in the middle of the city. This unit in particular has the most detailed pick on designer furniture from brands such as Herman Miller and Restoration Hardware. The kitchen is also fully equipped with Thermador appliances so you can live the Wanders & Yoo experience.

Top guest favourite
A spacious living room features a comfortable brown sofa and an armchair beside a decorative coffee table. Natural light enters through large glass doors draped with sheer curtains, illuminating the warm wood floors and elegant decor.
Flat in Panama City
5 out of 5 average rating, 78 reviews

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Top guest favourite
Flat in Marbella
5 out of 5 average rating, 7 reviews

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Experience Yoo Panama by world renown architect Philippe Starck. Massive unit 155 m2 / 1,700 ft2 ocean view apartment with an unobstructed view of Panama City/Pacific Ocean overlooking the Panama Canal, Casco Viejo & Cinta Costera. Views & location don’t get better than this. Each bedroom is a King Bed suite. The apartment is located on the prestigious Avenida Balboa. There is a grocery store and 3 of PA's most renown restaurants in the building. Blazing fast wifi at 500mgbs.

Guest favourite
Flat in Panamá
4.85 out of 5 average rating, 13 reviews

Casco Viejo / Penthouse w/ Terrace & Pool Access

Nuestro Penthouse, en el último piso de La Cuadra Residence, en Casco Antiguo, cuenta con terraza privada con vista al Océano Pacifico y su entrada al Canal de Panamá, Cerro Ancón, Casco Antiguo, Cinta Costera, Biomuseo, Puerto de Cruceros de Amador y el skyline de la hermosa Ciudad de Panamá. Contamos con acceso privado al área social y piscina, desde nuestra terraza. Nuestro Lobby cuenta con acceso privado al restaurante Ayala Vida, de autentica comida panameña.

Top guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in Panamá
4.98 out of 5 average rating, 155 reviews

Escape to the Heart of Casco with a Private Balcony

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top guest favourite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Flat in Panamá
4.96 out of 5 average rating, 125 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favourite
A modern dining area features a white table set for four, surrounded by stylish chairs. Large windows allow natural light to fill the space, revealing views of the city skyline. A sleek kitchen is visible in the background, showcasing a gas stove and granite countertops.
Flat in Panamá
4.93 out of 5 average rating, 106 reviews

k*| Delightful 1 BR w/King Bed in Calle 50

Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Guest favourite
Flat in Panamá
4.98 out of 5 average rating, 125 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Superhost
A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.
Flat in Panama City
4.89 out of 5 average rating, 158 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Guest favourite
A modern living space features a light-colored sofa accompanied by a round coffee table. A large television is mounted on a decorative wall behind the sofa. Natural light streams through tall windows dressed with sheer curtains, enhancing the cozy atmosphere.
Flat in Panamá
4.93 out of 5 average rating, 55 reviews

Elegant apartment with a view & the warmth of home

This apartment with the warmth of home, elegant and comfortable with spectacular views of the city, located in one of the best areas of Panama City, surrounded by places of interest such as restaurants, commerce and the most important banking area of ​​the city, and its proximity to the Iglesia del Carmen metro station provides easy transportation in and out of Panama City.

Popular amenities for Panama City apartment rentals

Quick stats about flat rentals in Panama City

  • Total holiday rentals

    Explore 2,770 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at € 9 per night before taxes and fees

  • Verified guest reviews

    Over 71,040 verified reviews to help you choose

  • Family-friendly holiday rentals

    850 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 990 rentals that welcome pets

  • Holiday rentals with a pool

    1,730 properties feature pools

  • Rentals with dedicated workspaces

    1,720 properties have a dedicated workspace

  • Wifi availability

    2,640 of Panama City holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)

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