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Apartment holiday rentals in Panama City

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama City

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Superhost
An indoor garden is showcased, featuring lush greenery and soft lighting. A glass roof allows natural light to illuminate the space, which is accented by warm-toned stone walls. Two stylish chairs are positioned nearby, creating a comfortable seating area.
Apartment in San Felipe
4.88 out of 5 average rating, 143 reviews

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES

Spectacular duplex penthouse in Panama City’s historic centre, 265 m² with balconies and private outdoor terraces. It features an indoor garden lounge, a dining room, and 3 bedrooms (plus a sofa bed in the studio). Recently renovated in a loft style, it offers a unique, exclusive and comfortable design, located in the best part of the historic centre, perfect for relaxing and unwinding. Kitchen, dishwasher, living room with washing machine, shared swimming pool, lift, 24/7 doorman. Children who cannot swim are not allowed. Wide range of leisure activities in the area.

Guest favourite
A modern living space features a sleek gray sofa and a circular coffee table, with a view of the city visible through large floor-to-ceiling windows. Two yellow chairs add a pop of color, enhancing the bright and airy atmosphere.
Apartment in San Francisco
5 out of 5 average rating, 46 reviews

New Modern Condo 1BR Best Location! Rooftop Pool

➤ Centrally located in San Francisco, one of the best neighborhoods in Panamá City. Enjoy the high floor view from your private Balcony! FREE EARLY CHECK-IN (subject to availability) ★ Close to everything! Walk 5-10 mins to the Best Restaurants, Supermarkets and Multiplaza: the best Mall in Panamá Travel with the comfort of being in your home! in this new, high floor, modern and minimalist full apartment with top of the line appliances, which is great for personal/business or family enjoyment

Top guest favourite
A modern living area features a comfortable sofa complemented by decorative cushions. A glass coffee table adds a sleek touch, with natural light streaming in through large windows showcasing city views. A dining table set for four is present, surrounded by stylish decor.
Apartment in Bella Vista
4.98 out of 5 average rating, 93 reviews

Modern City Stay | Prime Location | Pool & Gym

The unit is spacious with balcony & wondeful views, located in safe and prime location . Walking distance to Metro, Cinta Costera & Bay, Restaurants, Bars, Local Foods, Supermarkets. Location is known for being a vibrant area with a mix of upscale & local options. The unit offers Free High Speed Wi-Fi & Cable Smart TVs. The social areas have free Parking Lot, Swimming Pool, Gym, Office Space. The building features a Restaurant, Rooftop Bar with amazing 360° view, Coffee Shop & Nail Salon

Top guest favourite
Apartment in El Cangrejo
4.86 out of 5 average rating, 102 reviews

Family apartment 3 bedrooms pool wifi free parking

A pasos de Vía Argentina, y la parada del Metro Via Argentina en el corazón de El Cangrejo. Restaurantes, supermercados, tiendas, cafeterías, farmacias, el Parque Andrés Bello y todo lo que puedas necesitar se encuentra a pasos. La ubicación es inmejorable. En una calle tranquila pero cerca de todo. En El Cangrejo, el barrio elegido por los extranjeros de visita. Edificio familiar. Cerca de todos los puntos turísticos de la ciudad es ideal como base para conocer esta hermosa Ciudad.

Guest favourite
A cozy bedroom is featured, showcasing a spacious bed adorned with decorative pillows and a soft throw. Large windows offer a view of the city skyline, while modern artwork adds a touch of color to the walls. A wardrobe is positioned against one side.
Apartment in Bella Vista
4.89 out of 5 average rating, 121 reviews

Centrally located studio in Bella Vista

📍 Strategic Location! Studio Apartment in Bella Vista Compact, comfortable studio apartment, ideal for exploring the city on foot or by public transport. Best of the area: *Subway: Steps from Santo Tomás Station. *5-minute walk: Cinta Costera (Coastal Strip), Urracá Park, and supermarkets. *Close to: Calle 50, Calle Uruguay, and restaurants. ⚠️ Note: There is ongoing construction behind the building (visible from the balcony). Some noise may be noticeable during the day.

Guest favourite
A spacious bedroom is shown, featuring a large bed with white bedding against a soft blue wall. Two orange chairs are positioned by the window, which offers an expansive view. A bedside lamp and a small nightstand complement the modern furnishings.
Apartment in Bella Vista
4.86 out of 5 average rating, 29 reviews

YOO View | Chic Suite in front of the Cinta Costera

This 1Hb apartment offers you an exceptional experience. Discover it. Its ocean-view balcony is ideal for gazing at the sea and the city from above. King bed, walking closet and a private bathroom with vanity, double sink, fully equipped open kitchen, perfect for those who love to cook, share a wine or work. Includes dishwasher, private laundry area and a guest bathroom. If you're looking for luxury, comfort, and a prime location, this is the place.

Guest favourite
A spacious living area features a light gray sectional sofa and a dark coffee table, surrounded by a patterned area rug. A television is placed on a low console, while a dining area with dark chairs and a table is visible in the background.
Apartment in San Francisco
4.95 out of 5 average rating, 132 reviews

Cozy 2 bedroom Apt. in Panama City, Panama

Best lodging option, conveniently, located in the center of bustling Panama City. You’ll be staying in a spacious, cozy, fully equipped apartment, with fast internet access, cable TV, including all the popular streaming services. Near great dinning options, coffee shops, nightlife spots, city parks, high end shopping centers, and city transport to take you to all the popular tourist spots that Panama City has to offer. It’s a home away from home.

Guest favourite
The entrance to the building is framed by manicured trees and architectural elements. Large glass doors lead into the space, reflecting warm lighting from chandeliers overhead. A pathway lined with tiles guides the way, creating a welcoming approach.
Apartment in Bella Vista
4.98 out of 5 average rating, 44 reviews

Modern and luxurious apartment in Cinta Costera

Experience the luxurious PH Yoo overlooking the city in this elegant apartment with a king-size bed and floor-to-ceiling windows. Enjoy world-class amenities: swimming pool, gym, squash court, spa, and more. Prime location near tourist areas, restaurants, bars, and shopping malls. Inside the building there are dining options with exclusive discounts and free valet parking. Modern, spacious and sophisticated space for an unforgettable getaway.

Superhost
A modern living area features a comfortable, light grey sofa accompanied by two accent pillows. A round coffee table sits in front, and large windows provide a view of the city skyline. Natural light brightens the space, creating an open and airy environment.
Apartment in Bella Vista
4.86 out of 5 average rating, 124 reviews

Ph Quartier Marbella 18E apt with rooftop pool

Excellent apartment in the center of the city, high floor with excellent view, full kitchen, premium furniture, large balcony, room with hotel quality sheets, 4 minutes walk from the coastal strip av balboa, surrounded by restaurants and shops, safe area for walk. Excelente apartamento en el centro de la ciudad, piso alto con excelente vista, cocina completa, muebles premium, amplio balcón, a 4 minutos caminando de la cinta costera av balboa.

Superhost
A spacious studio apartment features large glass doors that open to a balcony, offering natural light and views. A plush bed sits in the center, complemented by a cozy seating area. Green and white patterned floor tiles enhance the aesthetic, while potted plants add a fresh touch.
Apartment in Panamá
4.84 out of 5 average rating, 127 reviews

Amazing Condo Close to Casco Viejo, Panama City

Serenity, practicality and comfort for all our guests while enjoying the local life in Panama is our main goal. La Manzana building is part of the new development in Santa Ana, an up and coming neighborhood steps away from Unesco World Heritage Site ‘Casco Viejo’. If you are looking to experience all the comfort that comes from modern amenities while melting into the charms of local life, this is the perfect place!

Superhost
A well-lit bedroom features a spacious bed with light-colored bedding, complemented by decorative wall art. Natural light enters through large glass doors, which open to a small terrace with greenery. A cozy armchair is positioned nearby, enhancing the room's inviting atmosphere.
Apartment in Panamá
4.83 out of 5 average rating, 41 reviews

King Bed, Creative Design Steps from Casco Viejo

Casco 114 is a stay created by travelers, for travelers. Located in the heart of Santa Ana, the creative district of Panama’s Casco viejo, it offers a king bed, full-size trundle, sofa bed, private terrace, washer/dryer, and unique decor. At PH Casco View: enjoy a saltwater pool, coworking space, stunning views of both the Old Town and the modern city, paid parking, and all the comforts for an unforgettable stay.

Superhost
A dining area is featured with a wooden table and four black chairs, complemented by woven placemats. A cozy gray sofa sits nearby, alongside a lamp with a light shade. The kitchen area contains dark countertops and organized shelves, with large windows providing a city view.
Apartment in Bella Vista
4.9 out of 5 average rating, 170 reviews

Spacious Executive Apartment

Perfect location in the bank zone. Only a 10 minutes walk of “cinta costera” & Urraca Park where you can make exercise with a view! We are 1 minute walk to a very nice and big supermarket where you can get supplies. Area full of good restaurants and bars. We will enjoy to give you tips of where to have dinner, and any tips on turistical activities during your stay.

Popular amenities for Panama City apartment rentals

Quick stats about apartment rentals in Panama City

  • Total holiday rentals

    Explore 540 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at €9 per night before taxes and fees

  • Verified guest reviews

    Over 15,080 verified reviews to help you choose

  • Family-friendly holiday rentals

    190 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 240 rentals that welcome pets

  • Holiday rentals with a pool

    360 properties feature pools

  • Rentals with dedicated workspaces

    390 properties have a dedicated workspace

  • Wifi availability

    520 of Panama City holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)

Destinations to explore