
Hotels in Panama City
Find and book unique hotels on Airbnb
Quick stats about hotels in Panama City

Total holiday rentals
Explore 190 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at €9 per night before taxes and fees

Verified guest reviews
Over 5,050 verified reviews to help you choose

Family-friendly holiday rentals
10 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 30 rentals that welcome pets

Holiday rentals with a pool
80 properties feature pools

Rentals with dedicated workspaces
140 properties have a dedicated workspace

Wifi availability
190 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
Top-rated hotels in Panama City
Guests agree: these hotels are highly rated for location, cleanliness and more.

Deluxe Room at Hotel Bardot Boutique
Welcome to Hotel Bardot Boutique, where classic luxury and sophisticated design meet in perfect harmony in the heart of the Old Town. Our 30 m² Deluxe Room has been designed to offer an intimate and elegant experience for two people. It features an imposing canopy bed, golden details and a warm atmosphere that invites absolute rest. The room incorporates a beautiful integrated bathtub, creating a romantic atmosphere that elevates every moment of your stay.
5.0 out of 5 average rating, 3 reviews
Private Twin | Shared Bathroom
This double room has 2 twin size bunk beds, air conditioning, shared bathroom with a showerand toiletries. This cozy place is super convenient, with easy access to shops, restaurants, public transportation, and popular spots like the “Mercado del Marisco”, Casco Antiguo, the Causeway, and more… The shared full kitchen will be the perfect place for you to hang out with other guests and cook up your favorite meals while you’re here!
4.75 out of 5 average rating, 4 reviews
Elegant King room • Private bathroom • Obarrio
Elegant King room with private bathroom in the heart of Obarrio. Equipped with a king-size bed, air conditioning, fast Wi-Fi, a desk, and a wardrobe. In the room, you'll find a coffee corner with a coffee machine, a kettle, tea, and herbal teas, ideal for relaxing at any time of day. Within easy walking distance to restaurants, supermarkets, cafes, the subway, and main services. Perfect for both vacations and business trips.
5.0 out of 5 average rating, 3 reviews
Comfort Room
Welcome to your retreat in the heart of the old town! This spacious room in our charming hotel combines historic charm with modern amenities for an unforgettable stay in Panama City. Located in an incredibly central location, you will be within walking distance of the main points of interest such as Historic Centers, Panama Interoceanic Canal Museum, Mola Museum, Restaurants, Nightclubs and restaurants.
4.63 out of 5 average rating, 16 reviews
Bedroom in downtown Panama with bathroom and shower
We are an accommodation opened in October 2020 located in downtown Panama City. We have several types of rooms. In this case, it is a room with 1 double bed. We offer continuous reception service, high-speed Wi-Fi, shared work area, room with snack and coffee vending machine and 24-hour security. Our rooms are fully equipped with a private bathroom with hot water, a desk, air conditioning and cable TV.
4.52 out of 5 average rating, 44 reviews
Deluxe Adapted for People with Reduced Mobility
Welcome to our adapted room on the first floor of Hotel Mio Panama, designed for people with reduced mobility. With 30 m², it combines an adapted, modern and elegant design. Enjoy comfort and independence, along with a practical setting in the heart of the city. The hotel also offers a gym, restaurant and a rooftop pool. Enjoy an unforgettable experience in a cozy and fully equipped environment.
5.0 out of 5 average rating, 3 reviews
Executive Suite Financial District/Pool·Gym
Elegant suite located in the Megapolis Hotel, in the heart of Panama City. Modern and comfortable space, ideal for business trips or tourism. Strategic location near the Financial District, restaurants, shopping malls, nightlife and tourist attractions of the city. Enjoy access to high-level common areas, pool, gym and amenities that combine meals, rest and entertainment in one place.
4.82 out of 5 average rating, 11 reviews
Hotel room #3 one block from the Metro.
Enjoy quick access to Panama City's most popular destinations, shopping malls, restaurants, and tourist areas. Hotel room with private bathroom, air conditioning, cable TV, 24-hour reception, and parking subject to availability. Close to restaurants and casinos. One block from the Metro station that takes you in 10 minutes to Albrook Mall, the largest shopping mall in Panama.
4.76 out of 5 average rating, 46 reviews
Beautiful small loft #3 - double size bed
Enjoy charming "Corcho rooms" in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs. "Corcho" is luckily situated in the central, restored part of Casco. Most of the buildings around are restored and the neighborhood is safe.
4.79 out of 5 average rating, 75 reviews
Deluxe King at Marinn Tropical Vibes, Free Parking
Discover a beachfront escape on Panama’s sun-kissed Perico Island, where thriving landscapes, bright colors, and modern comforts create an unforgettable stay. Relax in thoughtfully designed rooms with stunning ocean views, perfect for a romantic getaway or family vacation.
4.53 out of 5 average rating, 17 reviews
Single room for 2 with breakfast included
We are an Executive Hotel, located in the center of the beautiful city of Panama, near the Cinta Costera, Casco Antiguo, the Museum of Biodiversity, the Panama Canal, among other locations. Come and enjoy our services!
4.8 out of 5 average rating, 5 reviews
Your second home in Panama.
Our rooms are located in a prime area in the heart of the city's financial and banking sector. We are two blocks away, two stations from the Metro transportation system. 15 minutes from some Shopping Centers.
4.74 out of 5 average rating, 129 reviewsPopular amenities for Panama City hotels
Family-friendly hotels

Hotel Caracas Casco Viejo - 2 Queen Beds Room
4.56 out of 5 average rating, 277 reviews
Premium Double Room in the Heart of Panama
New place to stay
A beautiful room to rest in the old town
3.83 out of 5 average rating, 6 reviews
Hotel Santa Lucia. Good service and comfort.
New place to stay
JR Suite Room

Comfortable room with excellent view

Superior Room at Hotel Bardot Boutique
5.0 out of 5 average rating, 5 reviews
Your second home in Panama.
4.67 out of 5 average rating, 183 reviewsHotels with a pool

Near Plaza de la Independencia + Rooftop Pool. Bar.
New place to stay
Bristol Panama | Deluxe King Room | Downtown

Ramada Panama Centro | Two Queens | Outdoor Pool
4.4 out of 5 average rating, 10 reviews
TRYP Panama Centro | Tryp Double | City Strolls

Junior Suite Room at the 4-star Hotel Princess

Triple Room at the Hotel Pacific Coast
New place to stay
In the heart of the city, Hotel Central Park

Single Triple Family Room
4.79 out of 5 average rating, 121 reviewsHotels with a patio

Eshel Panama suites, Troy suite 08
5.0 out of 5 average rating, 4 reviews
Grand International Hotel
5.0 out of 5 average rating, 3 reviews
Light Room in the ORHO Hotel

Amazing Family Room w/ Shared Kitchen near Canal

Double Deluxe with Balcony - Viajero Hostels

Beautiful cabins, swimming pool, the best of Cerro Azul

coastal strip
4.0 out of 5 average rating, 3 reviews
Charming Studio w Two Double Beds
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- Things to do Panama
- Landmarks Panama
- Food tours Panama
- Tastings Panama
- Wildlife Panama
- Outdoors Panama
- Cultural tours Panama
- Cooking Panama






