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Apartment holiday rentals in Panama

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Superhost
A bright bedroom features a spacious bed with a textured blue throw and rolled towels at the foot. Large windows provide an unobstructed view of the ocean, while a bedside table and a mirror enhance the room’s design. Natural light fills the space.
Flat in Panama City
4.82 out of 5 average rating, 111 reviews

k*| Breathtaking Oceanview 1BR in Ave Balboa

** POOL IS ON MAINTENANCE UNTIL SEP 15** Experience luxury in this oceanfront 1-bedroom apartment on Balboa Avenue with stunning views of the Pacific Ocean, Casco Viejo, and modern Panama City. Fully equipped for long stays with A/C, Water, TV, cable, and WiFi. Located in a unique building with amenities like Poin, a zipline between buildings, plus restaurants like Cielo, Osaka, and Patria. Walk to Cinta Costera and a subway station. Everything you need is right here—your perfect Panama getaway!

Guest favourite
A spacious terrace features four hammocks suspended between columns, inviting relaxation with a view of the serene ocean. A dining table with surrounding chairs is positioned nearby, overlooking calm waters and lush greenery, enhancing the outdoor living experience.
Flat in Juan Gallego
4.88 out of 5 average rating, 222 reviews

Pebos Reef Apt 1 · Beachfront · Sea View Terrace

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Guest favourite
A modern living area is presented with a light-colored sofa and stylish accent cushions. A glass coffee table is paired with a white armchair and a vibrant blue side table. Floor-to-ceiling windows provide a clear view of the ocean and allow natural light to brighten the space.
Flat in Bella Vista
4.8 out of 5 average rating, 144 reviews

Ocean View Apt in Panama, Yoo&Arts

Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.

Guest favourite
A modern living area features a light-colored sofa and a wooden coffee table. Large glass sliding doors provide a clear view of the ocean and greenery outside. A decorative plant adds a touch of nature, while soft light fills the space.
Flat in Rio Hato
4.94 out of 5 average rating, 102 reviews

Ocean View Marina Stay in Buenaventura | By Alura

Enjoy an exceptional stay in this elegant and modern apartment, located on the top floor in the marina in Buenaventura, Panama’s most exclusive beach resort. It offers panoramic views of the Pacific Ocean and the Marina. The apartment is fully equipped with high-quality furniture and finishes, thoughtfully designed to provide both comfort and style. You’ll also have access to beach clubs, restaurants, and more, for a truly unforgettable resort experience.

Top guest favourite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Flat in San Francisco
5.0 out of 5 average rating, 87 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more

Top guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in San Felipe
4.99 out of 5 average rating, 207 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favourite
An expansive infinity pool reflects the skyline of Panama City and the nearby bay. Lounge chairs are arranged neatly along the poolside, allowing for relaxation while enjoying the panoramic views of the surrounding area.
Flat in Panama City
4.91 out of 5 average rating, 138 reviews

Impressive ocean and Panama City views

Enjoy a unique experience, a modern apartment with its own style, where every sunrise and sunset becomes a show. Enjoy breathtaking views of Panama City, the bay, and the Old Town from the comfort of your home. Unbeatable Location Located just 5 minutes from the charming Casco Viejo and the famous seafood market, and 10 minutes from the banking area. In addition, you will have a metro station and several bus stops just a few steps from the building

Superhost
Flat in Panama City
4.75 out of 5 average rating, 121 reviews

Apartment in the Causeway Amador

Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family

Superhost
Flat in San Felipe
4.8 out of 5 average rating, 110 reviews

Amazing experience 3BR 2BTH Casco Viejo w/Rooftop

Enjoy Panamanian culture from the center of Casco Viejo, where you'll discover colonial architecture, visit the area's best restaurants, nightspots, and rooftops. Quiet and comfortable apartment. Features a living room, dining room, equipped kitchen, work desk, 2 queen beds, 1 twin bed, 2 bathrooms, closets, air conditioning, balcony, barbecue, and outdoor dining area. We offer everything you need to have the best local experience!

Guest favourite
A modern living area features a white sectional sofa adorned with colorful cushions. A sleek coffee table sits in front of a mounted television. Large windows provide expansive views of the city skyline, enhancing the bright and airy feel of the space.
Flat in Bella Vista
4.89 out of 5 average rating, 196 reviews

Beautiful Apt, Best Location 2BR

Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.

Guest favourite
Flat in San Francisco
4.98 out of 5 average rating, 164 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favourite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Flat in San Felipe
4.91 out of 5 average rating, 129 reviews

The best view of the Old Town

Welcome to this charming accommodation in the heart of the Old Town, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you'll enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you'll find a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Popular amenities for Panama apartment rentals