
Apartment holiday rentals in Panama
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Top-rated apartment rentals in Panama
Guests agree: these apartments are highly rated for location, cleanliness and more.

Panoramic Casco Viejo Lookout in The Sands
exquisite apartment blends cozy comfort with sophisticated luxury. Every detail radiates elegance, from the plush, high-end furnishings to the warm, inviting ambiance. The open-concept living area is perfect for relaxing or entertaining, with breathtaking views of the UNESCO World Heritage Casco Viejo framing the horizon. The compact kitchen has modern appliances, sleek countertops, and all essentials. With Casco Viejo vistas, this stylish retreat is perfect for exploring culture and history.
4.94 out of 5 average rating, 77 reviews
Pebos Reef Apt 1 · Beachfront · Sea View Terrace
This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.
4.88 out of 5 average rating, 222 reviews
The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
4.98 out of 5 average rating, 134 reviews
Luxury apt in Panama City 2 Rooms 3 Baths
The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more
5.0 out of 5 average rating, 88 reviews
The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.
4.99 out of 5 average rating, 208 reviews
Ocean View | Rooftop Pool | Luxury Stay
Wake up to a stunning ocean view right from your window at BrisaMarina. This luxury apartment is located in the spectacular The Sands building, right on the Cinta Costera. The modern and cozy space features bright natural light, air conditioning, high-speed Wi-Fi, and a fully equipped kitchen for your comfort. You’ll be just minutes away from restaurants, beaches, and top attractions. Perfect for couples, business travelers, or weekend getaways.
4.97 out of 5 average rating, 97 reviews
Beautiful Apt, Best Location 2BR
Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.
4.89 out of 5 average rating, 196 reviews
Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
4.97 out of 5 average rating, 166 reviews
The best view of the Old Town
Welcome to this charming accommodation in the heart of the Old Town, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you'll enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you'll find a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.
4.92 out of 5 average rating, 132 reviews
Modern, central and comfortable (001)
Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!
4.87 out of 5 average rating, 151 reviews
LUXURY APT/ Sea View & Rooftop
Modern luxury apartment on the Cinta Costera, ideal for executives, couples or families. Large bedroom with ocean view, private bathroom, kitchen and appliances. Elegant design with 24/7 security, gym, swimming pools, 4 restaurants, bar and Sky Lounge. Prime location near supermarkets and excellent cuisine in Panama City. PANAMA
4.96 out of 5 average rating, 182 reviews
Panoramic Ocean View | The Sands
Wake up to breathtaking panoramic ocean views at The Sands. Enjoy a modern apartment with a fully equipped kitchen, high-speed WiFi, pool, gym, and an unbeatable location near Casco Viejo, Cinta Costera, and Panama City's top restaurants. Perfect for couples, business travelers, and long stays.
4.87 out of 5 average rating, 15 reviewsPopular amenities for Panama apartment rentals
Weekly apartment rentals

5B • 5 Bedroom Apt • 4 Baths • Ideal for 10 Guests
4.96 out of 5 average rating, 24 reviews
Luxury Apartment in Obarrio Rooftop & Pool
5.0 out of 5 average rating, 4 reviews
Luxury Stay & Panoramic Bay View in YOO Panama
4.82 out of 5 average rating, 11 reviews
Luxury Centric 2BR Apartment in Casco Viejo
4.97 out of 5 average rating, 38 reviews
Unique Luxury 3-story Loft at the Yoo
4.96 out of 5 average rating, 89 reviews
Casa Esmeralda Refined 120 m² Duplex in Casco Viejo
4.94 out of 5 average rating, 36 reviews
Historic Casa Donovan | Old Town & City Views
4.75 out of 5 average rating, 4 reviews
Modern studio with ocean view + POIN Panama
5.0 out of 5 average rating, 25 reviewsPrivate apartment rentals

Escape to the Pacific of Panama
5.0 out of 5 average rating, 19 reviews
Tropicool Casco Loft w/King Bed & Rooftop
4.99 out of 5 average rating, 77 reviews
Apartment in Panama City
4.89 out of 5 average rating, 89 reviews
Most Beautiful Loft in the Heart of Casco Viejo
5.0 out of 5 average rating, 36 reviews
Luxury Oceanfront Resort 22nd Floor View, 200°
4.85 out of 5 average rating, 73 reviews
Executive apartment on Avenida Balboa
4.71 out of 5 average rating, 49 reviews
24G Apartment in Wanders & Yoo Marbella with 3 bedrooms
5.0 out of 5 average rating, 3 reviews
Stunning loft in Buenaventura Golf&Beach Resort
5.0 out of 5 average rating, 45 reviewsApartment rentals with a hot tub

Ocean View Apt in Panama, Yoo&Arts
4.8 out of 5 average rating, 145 reviews
PH The Gray | Balcony Views · Pool · Gym
4.84 out of 5 average rating, 100 reviews
New Flat with Ocean + City Views
4.78 out of 5 average rating, 125 reviews
Tropical Paradise at Playa Bonita
4.93 out of 5 average rating, 118 reviews
Beachfront Paradise in a 5-star Resort
4.91 out of 5 average rating, 149 reviews
Spacious 4Br Beachside Getaway at Playa Escondida
4.95 out of 5 average rating, 149 reviews
Apartment #4 Greenscape Suite
4.9 out of 5 average rating, 113 reviews
Ocean View Apartment - Playa Escondida Resort
4.87 out of 5 average rating, 141 reviewsDestinations to explore
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