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Apartment holiday rentals in Panama

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Top-rated apartment rentals in Panama

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Top guest favourite
Flat in Panamá
5 out of 5 average rating, 13 reviews

Modern apartment in the heart of Obarrio

This apartment stands out for its privileged location in Obarrio, with a modern and cozy design. Located on the 14th floor, it offers a spectacular view, its decoration in neutral tones conveys serenity. The convenience of having two bathrooms makes it unique. Ideal for travellers looking for peace of mind and functionality. Located just a few steps from Calle 50 and the iconic El Tornillo building. You're surrounded by casinos, hotels and restaurants. Safe area for walking and enjoying the city.

Top guest favourite
A modern living space features an open kitchen with wooden cabinetry and a dining area. A curved gray sofa is complemented by yellow pillows, positioned next to a round coffee table. Natural light streams through blinds, illuminating the minimalist decor.
Flat in Panamá
5 out of 5 average rating, 82 reviews

New apartment on 50th Street

Enjoy a stylish experience at this centrally-located place. Direct access to bus lines and the Metro. Close to tourist sites and steps away from a variety of restaurants, grocery store, nightlife, casinos and blocks from the coastal strip, Iglesia del Carmen, and Parque Urraca. The old town is just minutes away by Uber. Close to shopping area. Soho Mall, Multi Plaza Mall, and Albrook Mall. Relaxing swimming pool for adults and children. Bar and restaurant, co-working, gym. You'll have a great time.

Top guest favourite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Flat in Panama City
5 out of 5 average rating, 36 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Superhost
Flat in Panamá
5 out of 5 average rating, 4 reviews

Incredible Renovated Apartment in Casco Viejo

Disfruta de un loft único en el corazón de Casco Viejo, ubicado en la emblemática Calle 4ta. Este apartamento ha sido totalmente remodelado, combinando a la perfección el encanto histórico de sus muros originales con un diseño moderno y elegante. La doble altura, la pared de piedra restaurada y los detalles artesanales en los pisos crean un ambiente acogedor y sofisticado. Su distribución abierta con sala, comedor y cocina integrada lo convierten en un espacio ideal para relajarse y compartir.

Guest favourite
A hammock sways gently between posts, overlooking calm waters that reflect a clear blue sky. In the distance, a lush island is visible, providing a picturesque backdrop. The green grass leads up to the water's edge, creating a serene outdoor space.
Flat in Juan Gallego
4.85 out of 5 average rating, 127 reviews

Pebos Reef, apt #2, Amazing views !!

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in Panamá
4.98 out of 5 average rating, 146 reviews

Escape to the Heart of Casco with a Private Balcony

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top guest favourite
An outdoor pool area is featured with modern sun loungers surrounding the illuminated water. Lounge furniture provides space for relaxation, while the skyline of the city is visible in the background against a twilight sky.
Flat in Panamá
5 out of 5 average rating, 55 reviews

Modern and luxurious Costera Cinta

Experience the luxurious PH Yoo experience with city views in this elegant apartment with king bed and floor-to-ceiling windows. Enjoy upscale amenities: swimming pool, gym, squash court, spa, and more. Privileged location close to tourist areas, restaurants, bars and malls. Inside the building there are gastronomic options with exclusive discounts and free valet parking. Modern, spacious and sophisticated space for an unforgettable getaway.

Guest favourite
An elegant living space features a light-colored sofa with decorative cushions, complemented by a round dining table set with place settings. Modern lighting fixtures are mounted on the ceiling, and a stylish kitchenette is visible in the background.
Flat in Panama City
4.89 out of 5 average rating, 37 reviews

Apartment with the warmth of home coastal strip

This cozy and stylish apartment offers the perfect blend of comfort and elegance, with stunning views of the city skyline, Cinta Costera, and Panama’s iconic Avenida Balboa. Located in one of the city’s top neighborhoods, you’ll be steps away from great restaurants, shops, and the historic Casco Viejo. With easy access to major roads, getting around the city is a breeze. Enjoy a unique, central stay that truly feels like home.

Top guest favourite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Flat in Panamá
4.97 out of 5 average rating, 116 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favourite
Flat in Panamá
5 out of 5 average rating, 117 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favourite
A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.
Flat in Panama City
4.9 out of 5 average rating, 153 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Top guest favourite
A spacious terrace features modern lounge chairs facing an infinity pool that blends with the ocean horizon. Clear blue skies and serene water create a tranquil setting. The surrounding palm trees add a touch of greenery to the area, enhancing the overall views.
Flat in Panamá
4.99 out of 5 average rating, 110 reviews

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM

Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA

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