
Apartment holiday rentals in Panama
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Panama
Guests agree: these apartments are highly rated for location, cleanliness and more.

Pebos Reef Apt 1 · Beachfront · Sea View Terrace
This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.
4.88 out of 5 average rating, 222 reviews
The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
4.98 out of 5 average rating, 134 reviews
Ocean View Apt in Panama, Yoo&Arts
Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.
4.8 out of 5 average rating, 145 reviews
k*| Breathtaking Oceanview 1BR in Ave Balboa
Experience luxury in this oceanfront 1-bedroom apartment on Balboa Avenue with stunning views of the Pacific Ocean, Casco Viejo, and modern Panama City. Fully equipped for long stays with A/C, Water, TV, cable, and WiFi. Located in a unique building with amenities like Poin, a zipline between buildings, plus restaurants like Cielo, Osaka, and Patria. Walk to Cinta Costera and a subway station. Everything you need is right here—your perfect Panama getaway!
4.83 out of 5 average rating, 115 reviews
Luxury apt in Panama City 2 Rooms 3 Baths
The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more
5.0 out of 5 average rating, 88 reviews
The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.
4.99 out of 5 average rating, 208 reviews
Beautiful Apt, Best Location 2BR
Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.
4.89 out of 5 average rating, 196 reviews
Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
4.97 out of 5 average rating, 166 reviews
The best view of the Old Town
Welcome to this charming accommodation in the heart of the Old Town, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you'll enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you'll find a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.
4.92 out of 5 average rating, 131 reviews
Modern, central and comfortable (001)
Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!
4.87 out of 5 average rating, 151 reviews
PH The Gray | Balcony Views · Pool · Gym
Wake up to panoramic views of Cerro Ancón from your private balcony — right in the heart of Calle 50, Panama’s financial and lifestyle hub. The Gray is a brand-new building offering resort-style amenities: rooftop pool, gym, and a fully equipped coworking space with high-speed Wi-Fi. You’ll also find restaurants and cafés inside the building itself.
4.84 out of 5 average rating, 100 reviews
LUXURY APT/ Sea View & Rooftop
Modern luxury apartment on the Cinta Costera, ideal for executives, couples or families. Large bedroom with ocean view, private bathroom, kitchen and appliances. Elegant design with 24/7 security, gym, swimming pools, 4 restaurants, bar and Sky Lounge. Prime location near supermarkets and excellent cuisine in Panama City. PANAMA
4.96 out of 5 average rating, 182 reviewsPopular amenities for Panama apartment rentals
Weekly apartment rentals

Panama City Sea View
4.94 out of 5 average rating, 17 reviews
Panoramic Casco Viejo Lookout in The Sands
4.94 out of 5 average rating, 77 reviews
Ocean View | Rooftop Pool | Luxury Stay
4.97 out of 5 average rating, 97 reviews
Luxury Apartment in Obarrio Rooftop & Pool
5.0 out of 5 average rating, 4 reviews
5B • 5 Bedroom Apt • 4 Baths • Ideal for 10 Guests
4.96 out of 5 average rating, 24 reviews
Luxury Centric 2BR Apartment in Casco Viejo
4.97 out of 5 average rating, 38 reviews
Unique Luxury 3-story Loft at the Yoo
4.96 out of 5 average rating, 89 reviews
Luxury Stay & Panoramic Bay View in YOO Panama
4.82 out of 5 average rating, 11 reviewsPrivate apartment rentals

Ocean View Suite Coastal Strip
4.79 out of 5 average rating, 34 reviews
“Modernity and Comfort in the City”
4.97 out of 5 average rating, 86 reviews
Tropicool Casco Loft w/King Bed & Rooftop
4.99 out of 5 average rating, 77 reviews
Luxury Oceanfront Resort 22nd Floor View, 200°
4.85 out of 5 average rating, 73 reviews
Hotel-Style Room at The Hub, San Francisco
5.0 out of 5 average rating, 8 reviews
Live the Wanders And Yoo Experience in Panama
4.98 out of 5 average rating, 44 reviews
Casa del Horno | A Piece of Panamanian History
4.93 out of 5 average rating, 74 reviews
Apartment in Panama City
4.89 out of 5 average rating, 89 reviewsApartment rentals with a hot tub

New Flat with Ocean + City Views
4.78 out of 5 average rating, 125 reviews
Beachfront Paradise in a 5-star Resort
4.91 out of 5 average rating, 149 reviews
Tropical Paradise at Playa Bonita
4.93 out of 5 average rating, 118 reviews
Spacious 4Br Beachside Getaway at Playa Escondida
4.95 out of 5 average rating, 149 reviews
Apartment #4 Greenscape Suite
4.9 out of 5 average rating, 113 reviews
Ocean View - Playa Escondida Resort
4.83 out of 5 average rating, 111 reviews
Luxurious apartment in Marbella
4.9 out of 5 average rating, 51 reviews
PH Yoo 44i – Ocean View Apartment
4.85 out of 5 average rating, 85 reviewsDestinations to explore
- Beach apartment rentals Panama
- Lakehouse rentals Panama
- Rentals with an accessible-height bed Panama
- Aparthotel rentals Panama
- Hotel rooms Panama
- Earth house rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with beach access Panama
- Rentals with a sauna Panama
- Pet-friendly rentals Panama
- Chalet rentals Panama
- Nature eco lodge rentals Panama
- Rentals with breakfast Panama
- Bed and breakfasts Panama
- Loft rentals Panama
- Boutique hotels Panama
- Container rentals Panama
- Tent rentals Panama
- Cottage rentals Panama
- Cabin rentals Panama
- Hostel rentals Panama
- Bungalow rentals Panama
- Holiday home rentals Panama
- Family-friendly rentals Panama
- Dome rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- House rentals Panama
- Rentals with a hot tub Panama
- Rentals with lake access Panama
- Beach house rentals Panama
- Guest house rentals Panama
- Treehouse rentals Panama
- Waterfront rentals Panama
- Villa rentals Panama
- Island rentals Panama
- Rentals with pools Panama
- Farm stay rentals Panama
- Boat rentals Panama
- Apartment rentals Panama
- Townhouse rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Tiny house rentals Panama





