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Apartment holiday rentals in Panama

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Superhost
A bright bedroom features a spacious bed with a textured blue throw and rolled towels at the foot. Large windows provide an unobstructed view of the ocean, while a bedside table and a mirror enhance the room’s design. Natural light fills the space.
Flat in Panama City

k*| Breathtaking Oceanview 1BR in Ave Balboa

** POOL IS ON MAINTENANCE UNTIL SEP 15** Experience luxury in this oceanfront 1-bedroom apartment on Balboa Avenue with stunning views of the Pacific Ocean, Casco Viejo, and modern Panama City. Fully equipped for long stays with A/C, Water, TV, cable, and WiFi. Located in a unique building with amenities like Poin, a zipline between buildings, plus restaurants like Cielo, Osaka, and Patria. Walk to Cinta Costera and a subway station. Everything you need is right here—your perfect Panama getaway!

4.82 out of 5 average rating, 111 reviews
Top guest favourite
Flat in Bella Vista

280 Degree Ocean View | 2 King Beds | 45 Day Min

Beautiful corner unit - 220 m2 / 2,400 ft2 apartment with a 280 degree unobstructed view of Panama City/Pacific Ocean overlooking the Panama Canal, Casco Viejo & Cinta Costera. Views & location don’t get better than this. V shape corner unit with 2 King Bed suites. The apartment is on the wonderful Avenida Balboa. There is a mini-mart on the corner and a brand new grocery store 3 blocks away. Blazing fast wifi at 500mgbs. This space is my personal home that I rent while traveling.

5.0 out of 5 average rating, 107 reviews
Guest favourite
A spacious terrace features four hammocks suspended between columns, inviting relaxation with a view of the serene ocean. A dining table with surrounding chairs is positioned nearby, overlooking calm waters and lush greenery, enhancing the outdoor living experience.
Flat in Juan Gallego

Pebos Reef Apt 1 · Beachfront · Sea View Terrace

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

4.88 out of 5 average rating, 222 reviews
Guest favourite
Flat in Panama City

5B • 5 Bedroom Apt • 4 Baths • Great for Groups

Apartment 5B is a modern 5-bedroom, 4-bath home designed for comfortable group stays, accommodating up to 10 guests with one king, three queens, and two single beds. It features a fully equipped kitchen, bright living area, fast WiFi, and spaces to relax or work. Centrally located in Panama City near restaurants, supermarkets, parks, and the waterfront. Guests enjoy full privacy, shared amenities including pool, gym, sauna, spa, and on-site support when needed.

4.95 out of 5 average rating, 21 reviews
Top guest favourite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Flat in San Francisco

Luxury apt in Panama City 2 Rooms 3 Baths

The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more

5.0 out of 5 average rating, 85 reviews
Top guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in San Felipe

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

4.99 out of 5 average rating, 205 reviews
Superhost
Flat in Panama City

Apartment in the Causeway Amador

Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family

4.75 out of 5 average rating, 120 reviews
Superhost
Flat in San Felipe

Amazing experience 3BR 2BTH Casco Viejo w/Rooftop

Enjoy Panamanian culture from the center of Casco Viejo, where you'll discover colonial architecture, visit the area's best restaurants, nightspots, and rooftops. Quiet and comfortable apartment. Features a living room, dining room, equipped kitchen, work desk, 2 queen beds, 1 twin bed, 2 bathrooms, closets, air conditioning, balcony, barbecue, and outdoor dining area. We offer everything you need to have the best local experience!

4.8 out of 5 average rating, 110 reviews
Guest favourite
A modern living area features a white sectional sofa adorned with colorful cushions. A sleek coffee table sits in front of a mounted television. Large windows provide expansive views of the city skyline, enhancing the bright and airy feel of the space.
Flat in Bella Vista

Beautiful Apt, Best Location 2BR

Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.

4.89 out of 5 average rating, 196 reviews
Guest favourite
Flat in San Francisco

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

4.98 out of 5 average rating, 164 reviews
Guest favourite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Flat in San Felipe

The best view of the Old Town

Welcome to this charming accommodation in the heart of the Old Town, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you'll enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you'll find a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

4.91 out of 5 average rating, 128 reviews
Guest favourite
A tranquil swimming pool is featured, surrounded by stone and wooden decking. Lounge chairs are positioned nearby, with a clear view of the ocean in the background. A pergola provides shaded seating, complementing the serene coastal environment.
Flat in San Carlos

3 bedroom apartment by the beach at Punta Caelo

Beautiful brand new and fully-equipped apartment in Punta Caelo, perfect for enjoying the beach on weekend getaways or long stays in the exclusive Punta Caelo condominium. Beautiful beach apartment in Punta Caelo, perfect for enjoying the beach on a weekend getaway or longer stays. This brand new apartment is located in the exclusive Punta Caelo development.

4.94 out of 5 average rating, 155 reviews

Popular amenities for Panama apartment rentals