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Apartment holiday rentals in Panama

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Guest favourite
A bright bedroom features a spacious bed with a textured blue throw and rolled towels at the foot. Large windows provide an unobstructed view of the ocean, while a bedside table and a mirror enhance the room’s design. Natural light fills the space.
Flat in Panama City
4.83 out of 5 average rating, 110 reviews

k*| Breathtaking Oceanview 1BR in Ave Balboa

** POOL IS ON MAINTENANCE UNTIL SEP 15** Experience luxury in this oceanfront 1-bedroom apartment on Balboa Avenue with stunning views of the Pacific Ocean, Casco Viejo, and modern Panama City. Fully equipped for long stays with A/C, Water, TV, cable, and WiFi. Located in a unique building with amenities like Poin, a zipline between buildings, plus restaurants like Cielo, Osaka, and Patria. Walk to Cinta Costera and a subway station. Everything you need is right here—your perfect Panama getaway!

Guest favourite
A spacious terrace features four hammocks suspended between columns, inviting relaxation with a view of the serene ocean. A dining table with surrounding chairs is positioned nearby, overlooking calm waters and lush greenery, enhancing the outdoor living experience.
Flat in Juan Gallego
4.88 out of 5 average rating, 221 reviews

Pebos Reef Apt 1 · Beachfront · Sea View Terrace

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Top guest favourite
Flat in San Felipe
4.98 out of 5 average rating, 130 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Guest favourite
A modern living area is presented with a light-colored sofa and stylish accent cushions. A glass coffee table is paired with a white armchair and a vibrant blue side table. Floor-to-ceiling windows provide a clear view of the ocean and allow natural light to brighten the space.
Flat in Bella Vista
4.8 out of 5 average rating, 143 reviews

Ocean View Apt in Panama, Yoo&Arts

Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.

Guest favourite
A spacious living area is highlighted by a large sectional sofa and a low wooden shelf displaying modern decor. Glass doors open to a balcony showcasing outdoor seating, with natural light illuminating the room. The tile floor adds a warm touch to the ambiance.
Flat in San Felipe
4.82 out of 5 average rating, 137 reviews

Stunning Terrace Among Ruins in Casco Viejo

Welcome to your Casco Viejo retreat! This spacious apartment, perfect for up to 8 guests, offers a unique blend of modern comfort and historic charm in Panama City’s most iconic neighborhood. Located in the heart of Casco Viejo. The highlight of this beautiful space is the stunning terrace nestled among historic ruins, where you can relax, enjoy a meal, or simply take in the timeless atmosphere. This is more than a stay – it’s an unforgettable experience.

Top guest favourite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Flat in San Francisco
5.0 out of 5 average rating, 85 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more

Top guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in San Felipe
4.99 out of 5 average rating, 203 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Superhost
Flat in Panama City
4.75 out of 5 average rating, 120 reviews

Apartment in the Causeway Amador

Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family

Guest favourite
A modern living area features a white sectional sofa adorned with colorful cushions. A sleek coffee table sits in front of a mounted television. Large windows provide expansive views of the city skyline, enhancing the bright and airy feel of the space.
Flat in Bella Vista
4.89 out of 5 average rating, 194 reviews

Beautiful Apt, Best Location 2BR

Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.

Guest favourite
Flat in San Francisco
4.98 out of 5 average rating, 163 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favourite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Flat in San Felipe
4.91 out of 5 average rating, 127 reviews

The best view of the Old Town

Welcome to this charming accommodation in the heart of the Old Town, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you'll enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you'll find a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Guest favourite
A tranquil swimming pool is featured, surrounded by stone and wooden decking. Lounge chairs are positioned nearby, with a clear view of the ocean in the background. A pergola provides shaded seating, complementing the serene coastal environment.
Flat in San Carlos
4.93 out of 5 average rating, 153 reviews

3 bedroom apartment by the beach at Punta Caelo

Beautiful brand new and fully-equipped apartment in Punta Caelo, perfect for enjoying the beach on weekend getaways or long stays in the exclusive Punta Caelo condominium. Beautiful beach apartment in Punta Caelo, perfect for enjoying the beach on a weekend getaway or longer stays. This brand new apartment is located in the exclusive Punta Caelo development.

Popular amenities for Panama apartment rentals