
Apartment holiday rentals in Panama
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Top-rated apartment rentals in Panama
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5B • 5 Bedroom Apt • 4 Baths • Ideal for 10 Guests
Welcome to Doña Raquel Residences, apartment 5B, a spacious 5-bedroom, 4-bathroom apartment in a central Panama City location, just minutes from Casco Viejo, Cinta Costera, restaurants, supermarkets, and shopping. Designed for families and groups, the apartment accommodates up to 10 guests and features a fully equipped kitchen, washer/dryer, fast Wi-Fi, A/C, and Smart TVs. Guests also enjoy access to our shared pool and rooftop amenities, including a gym, sauna, terrace, and massage room.
4.96 out of 5 average rating, 24 reviews
Pebos Reef Apt 1 · Beachfront · Sea View Terrace
This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.
4.88 out of 5 average rating, 222 reviews
Stunning Terrace Among Ruins in Casco Viejo
Welcome to your Casco Viejo retreat! This spacious apartment, perfect for up to 8 guests, offers a unique blend of modern comfort and historic charm in Panama City’s most iconic neighborhood. Located in the heart of Casco Viejo. The highlight of this beautiful space is the stunning terrace nestled among historic ruins, where you can relax, enjoy a meal, or simply take in the timeless atmosphere. This is more than a stay – it’s an unforgettable experience.
4.82 out of 5 average rating, 142 reviews
Luxury apt in Panama City 2 Rooms 3 Baths
The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more
5.0 out of 5 average rating, 87 reviews
The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.
4.99 out of 5 average rating, 208 reviews
Ocean View | Rooftop Pool | Luxury Stay
Wake up to a stunning ocean view right from your window at BrisaMarina. This luxury apartment is located in the spectacular The Sands building, right on the Cinta Costera. The modern and cozy space features bright natural light, air conditioning, high-speed Wi-Fi, and a fully equipped kitchen for your comfort. You’ll be just minutes away from restaurants, beaches, and top attractions. Perfect for couples, business travelers, or weekend getaways.
4.97 out of 5 average rating, 97 reviews
Apartment in the Causeway Amador
Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family
4.75 out of 5 average rating, 121 reviews
Amazing experience 3BR 2BTH Casco Viejo w/Rooftop
Enjoy Panamanian culture from the center of Casco Viejo, where you'll discover colonial architecture, visit the area's best restaurants, nightspots, and rooftops. Quiet and comfortable apartment. Features a living room, dining room, equipped kitchen, work desk, 2 queen beds, 1 twin bed, 2 bathrooms, closets, air conditioning, balcony, barbecue, and outdoor dining area. We offer everything you need to have the best local experience!
4.8 out of 5 average rating, 110 reviews
Beautiful Apt, Best Location 2BR
Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.
4.89 out of 5 average rating, 196 reviews
The Sands | Stunning Ocean View
Experience the best of Panama City at The Sands. Enjoy stunning ocean views, a stylish and comfortable apartment, high-speed Wi-Fi, a fully equipped kitchen, Smart TV, and premium amenities including a pool, gym, coworking space, cinema, and more. Located on Avenida Balboa, you're just minutes from Casco Viejo, Cinta Costera, top restaurants, nightlife, and the city's main attractions. Perfect for business or leisure.
4.63 out of 5 average rating, 8 reviews
Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
4.98 out of 5 average rating, 164 reviews
The best view of the Old Town
Welcome to this charming accommodation in the heart of the Old Town, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you'll enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you'll find a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.
4.92 out of 5 average rating, 131 reviewsPopular amenities for Panama apartment rentals
Weekly apartment rentals

Panama City Sea View
4.94 out of 5 average rating, 17 reviews
“Modernity and Comfort in the City”
4.97 out of 5 average rating, 86 reviews
Luxury Stay & Panoramic Bay View in YOO Panama
4.82 out of 5 average rating, 11 reviews
Panoramic Casco Viejo Lookout in The Sands
4.95 out of 5 average rating, 76 reviews
The Yellow by Sukha | Metro Vía Argentina
4.6 out of 5 average rating, 5 reviews
Ocean View Suite Coastal Strip
4.79 out of 5 average rating, 34 reviews
Casa Esmeralda Refined 120 m² Duplex in Casco Viejo
4.94 out of 5 average rating, 36 reviews
Old Town & Ocean View
4.9 out of 5 average rating, 72 reviewsPrivate apartment rentals

Sea view | Infinity pool + POIN Panama
4.94 out of 5 average rating, 17 reviews
Luxury Oceanfront Resort 22nd Floor View, 200°
4.85 out of 5 average rating, 73 reviews
Oceanfront Retreat | Balcony + Pool + Beach
5.0 out of 5 average rating, 14 reviews
Casa del Horno | A Piece of Panamanian History
4.93 out of 5 average rating, 73 reviews
PH Yoo 44i – Ocean View Apartment
4.85 out of 5 average rating, 84 reviews
Panamá Pacífico P.H. Centriqo: Close to Everything.
5.0 out of 5 average rating, 32 reviews
Escape to the Pacific of Panama
5.0 out of 5 average rating, 19 reviews
Hotel-Style Room at The Hub, San Francisco
5.0 out of 5 average rating, 7 reviewsApartment rentals with a hot tub

Ocean View Apt in Panama, Yoo&Arts
4.8 out of 5 average rating, 144 reviews
New Flat with Ocean + City Views
4.78 out of 5 average rating, 125 reviews
Beachfront Paradise in a 5-star Resort
4.91 out of 5 average rating, 149 reviews
Tropical Paradise at Playa Bonita
4.93 out of 5 average rating, 117 reviews
Apartment #4 Greenscape Suite
4.9 out of 5 average rating, 111 reviews
Spacious 4Br Beachside Getaway at Playa Escondida
4.95 out of 5 average rating, 149 reviews
Ocean View Apartment - Playa Escondida Resort
4.87 out of 5 average rating, 141 reviews
View and Comfort Apartment with Home Warmth
4.88 out of 5 average rating, 26 reviewsDestinations to explore
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