
Guest house holiday rentals in Upstate South Carolina
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Top-rated guest house rentals in Upstate South Carolina
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

Scenic Loft in the Woods
Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!

The Cottage in Spartanburg
This charming & private studio cottage is located in Spartanburg's downtown historic district Hampton Heights. Guests will find a comfortable foam mattress sofa bed (no bars or springs), full bathroom, closet, & complete kitchen amenities. Located less than a mile from restaurants, bars, m-league ball park & shops of Downtown Spartanburg, and close to Converse Univ., VCOM, and Wofford College, this cozy studio cottage is the perfect place to rest your head after a busy day visiting the Upstate.

Historic 19th Century Cabin/Guest House
This 19th century cabin is your perfect cozy getaway. This guest house is located on a 3.5 acre property, secluded from the historic neighborhood, though it's just 3 miles from downtown Greenville and the Bon Secours Wellness Arena. Less than a mile to the Swamp Rabbit Trail, this cottage is perfect for jaunts to downtown Greenville, Furman University, Paris Mountain, Travelers Rest and Unity Park! Micro weddings and events are available upon request and approval with applicable fees applied.

Modern Cabin Retreat w/ Sauna
This space was designed with love and care and the hope that all who stay here feel relaxed and connected to nature. We recently added a cedar barrel sauna that heats up quickly and is user friendly. Often we don’t see guests but I’m always available for questions and recommendations. We live "next door" on the same property with our two young sons. The cabin is located in a neighborhood, so while it hopefully feels removed from any hustle and bustle, there is access to many conveniences.

Nishleigh's Nook - West End Downtown Greenville
Welcome to your cozy retreat in the West End of Downtown Greenville! This newly constructed, detached garage studio near the up and coming West End Village, Unity Park, and downtown offers easy access to the city's best entertainment, boutique shops, and vibrant food scene. Enjoy a queen-sized memory foam bed, a fully equipped kitchen, and a dedicated dining area. High-speed Wi-Fi and a smart TV are included. Perfect for a peaceful escape with all the comforts you need for a memorable stay.

The Cottage at Old Oaks Farm
Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

Newly renovated guesthouse!
Relax at the MartInn, a newly renovated guesthouse only 20 minutes from downtown Athens, Ga. This one bedroom guesthouse is situated on a peaceful, wooded lot. Enjoy a cup of coffee on the deck, and then scramble some farm fresh eggs provided by the host’s chickens. The guesthouse is within 10-15 minutes of the Firefly Bike Trail, the North Oconee River Greenway, and Watson Milll Bridge State Park. Also nearby is the Broad River Outpost to rent kayaks for a float down the Broad River.

Mountain Edge Loft
Private loft apartment on 25 wooded acres, sits separate from main farm house. Private deck overlooking the woods. Everything you need for a cozy stay. Located on the edge of the Blue Ridge Escarpment with lakes Jocassee and Keowee just a few miles away. Numerous state parks, hiking, biking , waterfalls and kayaking or just peace and quiet. We are a sustainable homestead with an organic garden, chickens ,quail, dogs and cats. Our water comes from a natural spring.

Foothills Favorite
Custom designed 1 bedroom suite in the Lake Bowen/Landrum/Inman area. Comfortable yet sleek space tucked above a semi-detached garage; private entry & stairway to suite. Private deck overlooks green spaces, wooded area & Lake Bowen (best views late fall and winter). Enjoy mountain views at nearby Lake Bowen park, local wineries, and scenic highways. Minutes from Landrum & Tryon & Equestrian Center.

Shou-Sugi-Ban Retreat on the Saluda River
The Shou-Sugi-Ban Guest House is 5 miles from Greenville city center and West Greenville, yet you'll feel like you've escaped it all with the rush of the river and surrounding trees. This cozy, custom space has a king-size bed, and two sets of French doors leading out to a private deck. No matter where you are in the space, you'll have views of the 700 ft of Saluda river frontage.

Sally's Cottage
Couples retreat located 6 miles from downtown Greenville and the Swamp Rabbit Trail in a comfortable country setting. Wake up to a beautiful woods view through a large bay window and wildlife that surrounds the cottage (deer, birds and squirrels). Experience the beauty of the country in the city! Enjoy the eclectic collection of art and design in this cute little cottage.

Modern guesthouse in downtown TR
Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more! Enjoy a stylish, relaxed stay at our centrally-located place. Whether you're an outdoor enthusiast or fun-loving foodie, you'll find something just for you nearby. Only a short drive to downtown Greenville, Furman University or Paris Mountain. Within an hour drive of Asheville and Clemson University!
Popular amenities for guest house rentals in Upstate South Carolina
Family-friendly guest house rentals

Holly Hideaway! 10 Highway miles to Clemson U!

The Nest; private tiny home @Reblooming Rose

Bungalow on a 3 acre mini farm

Cozy Cottage - 5 miles from TIEC

1 Mile To Downtown Asheville, Pet Friendly

Lit'l Bit O' Heaven- Rocky Top Lodge

La Bella Farm

Cabin in the Pines
Guest house rentals with a patio

Cozy Rustic Lakefront Cabin

Modern Studio near downtown

Yes please we need you! Spacious w/ amazing view!

The Nest, Charming Country Setting south of Athens

Country-Clubhouse Tiny Home. Close to downtown!

Starswept Studio–Near GSMNP, BRP, Food and Skiing

Probart House - historic and 1 block from Main St

The Woodlen: Studio with Views/Hot tub/ fire pit
Guest house rentals with a washing machine and dryer

Explore the Woods from a Quiet Apartment near Sierra Nevada

Guest House at Lake Hartwell

Art, Biking, Food, and Shopping in Watkinsville

MeadowHill Guesthouse - Mountain view-3 mi to town

⭐️⭐️⭐️⭐️⭐️Casita Blanca 🚶🏽➡️Dining, BREWS,SHOPS📍DTWN📍LUX

Peaceful Guesthouse on 15 Acres with Pool

Pisgah Hideaway Studio

Tryon Foothills Getaway - NC wineries! - TIEC
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- Blue Ridge Parkway
- The North Carolina Arboretum
- Gorges State Park
- Table Rock State Park
- Chimney Rock State Park
- Ski Sapphire Valley
- Lake Lure Beach and Water Park
- Jump Off Rock
- Wade Hampton Golf Club
- Tryon International Equestrian Center
- Victoria Valley Vineyards
- Discovery Island
- Haas Family Golf
- Carl Sandburg Home National Historic Site
- Burntshirt Vineyards
- City Scape Winery
- Saint Paul Mountain Vineyards
- Overmountain Vineyards
- Wellborn Winery
- Russian Chapel Hills Winery
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