
Holiday rentals with lake access in Seneca
Find and book unique lake access rentals on Airbnb
Top-rated rentals with lake access in Seneca
Guests agree: these rentals with lake access are highly rated for location, cleanliness and more.

Lake Keowee Waterfront Cottage - Private Retreat
Lake-front retreat w/ unbelievable sunsets, swimming & kayaking, tucked in between the Cliffs & the Reserve, 30 miles west of Greenville. Private park-like setting for a couples getaway. Updated one-bedroom small cottage w/ living room, kitchen, bath, laundry, AC/heat. The entire property is included w/ your cottage rental; 1.1 acres, 800 ft of lake shoreline, a dock, a pier, a sunset deck, a social pavilion, waterfront hot-tub. It is a private lake experience; nothing really compares - unique!

Destination Keowee
A rustic industrial style Lake Keowee lakefront escape that places you right on a panoramic point in a private cove. Welcome the outdoors in with the 6ft kitchen hinge bar window to the upper deck or enjoy the 6-seat hot tub on lower deck. Deep water dock tie off space is available. Guests enjoy the use of 2 standup paddle boards, and lakeside fire pit (guest provide firewood). Great cove sunsets! 15 minutes to Clemson and 1 min Lighthouse Restaurant. Please read all details prior to booking!

Hartwell Hideaway – Dock, Kayaks & Fire Pit
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Hey Frame: Modern A-frame Cabin on Lake Hartwell
Featured in AJC as one of Georgia's top Airbnb's! We designed our lakefront A-frame cabin to provide the perfect getaway, and we love sharing our home with you. Wake up to sunrises over the lake while you sip coffee on the large deck or drink hot cocoa by the fire pit. Our modern kitchen also begs to be cooked in. In warmer months, enjoy swimming, kayaking, or paddle boarding off the private dock. Whether you want to relax or work on spreadsheets, you'll enjoy a beautiful view while doing so.

Lakefront Cabin • Hot Tub • Kayak/Canoe • Sleeps 6
Wake up to peaceful lake views, sip coffee on the porch, and spend the day kayaking or swimming from your private dock. This lakefront cabin is tucked away on Whitewater Lake in the South Carolina mountains, minutes from Lake Jocassee, and sleeps 6 guests. It’s the perfect getaway for couples, families, or friends looking to escape into nature. After a day exploring waterfalls, hiking nearby state parks, or boating on Lake Jocassee, come back and unwind in the hot tub overlooking the water.

Beautiful Lake Keowee Condo with great Amenities
"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"

Cozy Lake House 5 miles from Clemson w Dock
Only 5 miles from Clemson's campus, this retreat is perfectly situated on almost a full acre. You’ll love the cozy feel, with lots of amenities, including a well stocked kitchen, three-season screened-in porch, & open floor plan. Though the house isn’t directly on the water, our private dock on Hartwell is only a 1-2 min walk away! Nestled between Greenville and the mountains, this home is great for Clemson trips, lake adventures, close night life, restaurants, family entertainment, & more!

Hidden Lake Sanctuary
Recently remodeled and boasting 3000 sq ft, this home offers comfort and serenity. Tucked away in a peaceful cove feeding into Lake Keowee, it’s the perfect escape for nature lovers-especially kayakers. The property comes fully equipped with kayaks and paddle boards. Please note: Access to the dock involves a very steep descent, and the return hike can be challenging—best suited for active guests. Unwind in the private hot tub on the deck or gather around the cozy fire pit.

Lake Keowee Cabin: Peaceful and Bright
Welcome to Lizard Lodge. Relax in this quaint lake cabin with a mountain home vibe nestled in Northern Seneca on Lake Keowee. Enjoy the serenity of a beautifully modern 3-bedroom, 2.5 bath vacation cabin in a quiet gated cul-de-sac with scenic surroundings. On early mornings you can spot wildlife including deer and wild turkeys. Excellent location on the lake a few hundred feet away from a boat ramp. Come to relax, have fun on the lake or even enjoy a romantic escape.

Lakefront dock *hot tub* Anderson/Clemson king bed
Relax & enjoy the beautiful views of lake Hartwell from the front porch daybed swing, hot tub, or private dock. Sleep in a king size bed wrapped in cool cotton linens, a towel warmer, soaking tub with TV, & a breville espresso maker. Located w/i 10 minutes of many restaurants. Less than 20 min. to downtown Anderson Pendleton or Clemson. This prime location on lake Hartwell is a 10 minute boat ride to Portman Shoals Marina, the Galley restaurant, & Green Pond Landing.

Hartwell Escape 6 mi to Clemson Beautiful views
We recently purchased this gorgeous home on Lake Hartwell, in a secluded cul-de-sac in a quiet neighborhood (6 miles to Clemson..ALL BACKROADS) You will have the entire bottom floor with separate entrance . Enjoy beautiful lake views on the covered porch or from our dock. A Private Neighborhood Boat ramp is 25 feet from our home. Bring your boat, use our dock, space for multiple trailers. Driveway parking. Dogs Welcome! ($25 pet fee/entire stay)

Getaway on Lake Hartwell: Pontoon Rental, Clemson
Our 3 bedroom house is located on Lake Hartwell and is just a 15 min drive to Clemson University. You can enjoy access to the dock and beach which are a quick golf cart ride away. We have paddle boards on the dock and kayaks, coolers, bagged ice, fishing poles etc upon request. Off the back of the detached garage there’s a furnished screened-in deck with a grill that overlooks the end of the cove and fire pit below.
Popular amenities for lake access rentals in Seneca
Lake access house rentals

Lakefront+Near Clemson+Dock+Kayaks+Putting Green

Lake Escape

Anchor Point, Lake Retreat - Clemson, 2-story dock

Dujardins Keowee Waterfront Home

Johnsons Cove - Lakefront Retreat With EV Charger

Lake House Retreat Near Clemson

Point Lot, Boat and PWC Rental

Clemson Lake House - Dock, Hot Tub, Kayaks
Apartment rentals with lake access

Friendship Lake Apartment

Condo and Lake Keowee

TigerTown Tranquility | Lakeview Condo near Campus

Lake Hartwell - Hartwell Villa 8A

Lake views all around!

Gameday Getaway on Lake Hartwell - close to campus

"Honeysuckle" Comforts of home in Mt. Wilderness

3BR Ground floor condo - 2.4 Miles to Death Valley
Lake access cottage rentals

Waterfront cottage w/deep dock 17 miles to Clemson

The Blue Pine - A Cozy Updated Lakeside Cottage

Cottage on the Lake

South Cove Cottage ~ Lake Keowee

Lakefront cottage with a view, near Clemson

Sunset Cottage Lake Hartwell

Cozy 3 BR 2 BA Cottage With Beautiful Lake Views!

Lake Daze on Keowee
Quick stats about holiday rentals with lake access in Seneca

Total holiday rentals
Explore 20 holiday rentals in Seneca

Nightly prices starting at
Seneca holiday rentals start at € 94 per night before taxes and fees

Verified guest reviews
Over 720 verified reviews to help you choose

Family-friendly holiday rentals
20 properties offer extra space & child-friendly amenities

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wifi availability
20 of Seneca holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests – averaging 4.9 out of 5!
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- Rentals with lake access Oconee County
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- Rentals with lake access United States
- Black Rock Mountain State Park
- Gorges State Park
- Table Rock State Park
- Clemson University
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- Bell Mountain
- Jump Off Rock
- Bon Secours Wellness Arena
- Anna Ruby Falls
- Unicoi State Park and Lodge
- Chattooga Belle Farm
- Carl Sandburg Home National Historic Site
- Fred W Symmes Chapel
- Devils Fork State Park
- Jones Gap State Park
- Falls Park On The Reedy
- DuPont State Forest
- Dillard House Restaurant
- Paris Mountain State Park
- Peace Center
- Looking Glass Falls
- Fluor Field at the West End
- Georgia Mountain Coaster




