
Villa holiday rentals in Panama City
Find and book unique villas on Airbnb
Top-rated villa rentals in Panama City
Guests agree: these villas are highly rated for location, cleanliness and more.

Spacious Mountain Getaway in Paradise Cloud Forest
Private Villa located at Chagres National Park; a rainforest reserve only 30 minutes away from the airport and 50 minutes from Panama City. At 1,007 meters altitude, you will enjoy the perfect climate, bird watching, beautiful river walks, waterfalls, and many hiking trails full of wildlife, enjoy our mountain's pure air or simply relax in Nature. Bring the whole family to this great place with lots of room for fun. Bring your pets our land is completely fenced, they can run free in a vast space

5BR House in Panama City w/ Pool & King Beds
Enjoy a family or friends' getaway in this modern, newly remodeled house. This property boasts 5 bedrooms, 4.5 bathrooms, 10 beds, and can comfortably accommodate up to 15 guests. The house also features a private outdoor pool, where you can soak up the sun and cool off on hot days, all while being in a central location, just meters away from malls, supermarkets and night life. It's fully furnished with everything you could possibly need to ensure your stay is as comfortable as possible.

Historic Apartment - Balcony in Old Town
🇵🇦Vive la esencia del Casco Antiguo en este apartamento único, diseñado por el arquitecto Sebastián Paniza, conocido por su labor en restauración del Casco Histórico. Sus techos altos, ventanales coloniales y barandales de hierro forjado combinan historia y confort moderno. 🌿 Desde el balcón disfruta calles empedradas y fachadas coloniales. La sala con lámpara tipo candelabro, entrepiso abierto y cocina funcional es ideal para quienes valoran diseño, cultura y ubicación privilegiada.

Summit View Guest House Cerro Azul Panama
We have two properties in one estate in Cerro Azul. A guest house as well as an apartment. We are delighted to be able to welcome your entire family, including grandma and grandpa to our slice of paradise. Your experience here promises to be a perfect blend of relaxation, adventure, and breathtaking beauty. Our property boasts a sprawling lower balcony with unparalleled vistas. The guest house and apartment, along with the undercover terrace, pool and spa, are available for your enjoyment.

Villa La Vista-Panama's majestic mountain hideaway
Welcome to our Villa in Panama's Chagres National Park! We have installed a brand new spa heater in our pool (20Nov24) to enjoy breathtaking views of the surrounding mountain range. Take a dip in our stunning infinity pool, offering picturesque landscapes. Ultimate relaxation during sunset evenings in our inviting hot tub. A gym station you can stay fit. Jefferys Tamarin monkeys at our feeding station. Unwind in a hammock or enjoy a romantic poolside swing. Relax on the outdoor bar stools.

Villa El Cangrejo
Bienvenidos a Villa El Cangrejo, un refugio premium en el corazón de la ciudad. Con 800 m², esta propiedad es ideal para 14 personas. Ofrece 7 dormitorios, 7 baños, cocina completamente equipada, piscina, gimnasio y cancha de baloncesto. Disfruta de una sala de cine privada, amplia terraza de 200 m², patio frontal de 50 m², mesa de ping-pong, air hockey, videojuegos, dardos, futbolito, juegos de mesa y wifi. Vive una estadía inolvidable en un ambiente acogedor y completamente equipado.

In the Last Place in the World (6 guests)
Come spend a few days relaxing away from the hustle and bustle. Share as a family or partner of this beautiful and comfortable Villa all for you as a family or partner. Live the experience of having all in one place to spend a beautiful, rainy evening or be sunny. Comfortable and beautiful space for 6 people. (Adults and children). Located in Chagres National Park surrounded by greenery but just 45 minutes from town with cool/cold weather. You deserve this experience!

La Semilla | Jungle Mansion | Panama City
Just one hour from Panama City, you will find La Semilla | Jungle Mansion in the Cerro Azul cloud forest, bordering the Chagres National Park. La Semilla is a perfect private escape to relax or party in serene privacy. Boasting 7 luxurious king bedrooms suites all with A/C, flatscreens, wi-fi, en suite bathrooms and memory-foam mattresses. Amenities: bar, chef/restaurant, jacuzzi, billiards, movie lounge, and pool.

Beautiful House in Panama w/ King Beds + Pool
Beautiful home in Punta Paitilla with 6 bedrooms, 5.5 bathrooms and 8 beds, ideal for up to 16 guests. Enjoy a private pool, an on-site gym, and modern, comfortable spaces designed for families, groups, or business travelers. The layout offers privacy, style, and convenience. Located in one of Panama City’s most exclusive areas, just steps from shopping centers, restaurants, supermarkets, and the Cinta Costera.

Villa Helena Studio 1 Apt Cerro Azul
One bedroom cottage with private kitchen and bathroom in a peaceful compound with shared pool. Internet and free parking available. Laundry facilities available for longer stays. Cook your own meals, or have me cook some authentic Caribbean dishes like curries, or use the restaurant available next door. Surrounded by nature and access to trails, waterfalls, rivers, swimming holes.

Villa Helena 2 Bedrooms Cerro Azul
Forget your worries in this spacious and serene space surrounded by nature in a gated community. A home away from home. 2 bedrooms for 4 adults. Your own kitchen, dining/living area, 2 washrooms and 2 bedrooms in a private villa with a pool. Cook your own food, BBQ on a gas grill or check out the restaurants in the community.

Pleasant Villa de Playa Villas Decameron Rio Hato
In this accommodation you can breathe tranquility: relax with the whole family, excellent view of the Golf course access to the private beach club we have 24-hour security, quiet place to relax and have fun with the family.
Popular amenities for villa rentals in Panama City
Private villa rentals

Pleasant Villa de Playa Villas Decameron Rio Hato

Beautiful House in Panama w/ King Beds + Pool

La Semilla | Jungle Mansion | Panama City

Villa La Vista-Panama's majestic mountain hideaway

In the Last Place in the World (6 guests)

Historic Apartment - Balcony in Old Town

Villa Helena Studio 1 Apt Cerro Azul

Villa Helena 2 Bedrooms Cerro Azul
Luxury villa rentals

Beautiful Villa in Playa Escondida

House with an oceanfront pool

Casa Laguna - luxury beach front house with pool

Beachfront Villa - Island Getaway for 11 in Saboga

Cozy Villa in Playa Escondida
Villa rentals with a pool

Villa Playa Caracol, 3 Bedrooms, Pet Friendly

Cheerful 2-bedroom villa with shared pool

Entire Villa with pool in front of beach!

Gorgeous Pool View Two BR Beach Villa

Villa with pool, soccer field and stream

Caribbean Beach House with Pool

Bahia Breeze 3 bdrm nature sanctuary with pool

Villa in Playa Coronado *Paradise Point Community*
Quick stats about villa rentals in Panama City

Total holiday rentals
Explore 10 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at € 69 per night before taxes and fees

Verified guest reviews
Over 340 verified reviews to help you choose

Family-friendly holiday rentals
10 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 10 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wifi availability
10 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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- Things to do Panama
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