
Holiday rentals with lake access in Santee
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Top-rated rentals with lake access in Santee
Guests agree: these rentals with lake access are highly rated for location, cleanliness and more.

Log home on Lake Marion inlet w/private dock.
Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

The Turtle's Nest
Locally known as the "Turtle's Nest", this getaway will let you be close to all the action. Located on Goat Island, 2nd row back, right off the big water. Boat ramp, boatslip, and restaurant only .3 miles away. Boatslip & ramp included. Remodled to a farmhouse feel, this 3 bedroom, 1 bath has 2 king beds & two singles. Two single beds share the same space as living room. Great retreat after a long day of fishing, or hanging out with family and friends. Be back fast to unwind by the firepit.

The Lake House at Turtle Cove: Cozy relaxing
Nice lake home on a cove that connects to the lake. FIBER HIGH SPEED INTERNET JUST ADDED. JUST ADDED TV's IN BEDROOMS Very quite, private and relaxing. Located 20 minutes from Santee and 1 hour from downtown Charleston. All your streaming services are avalible. This is a great place to disconnect, relax, and enjoy yourself. If you fish , this is on a lake known for great fishing featuring the big blue cat fish. Or if you just want to enjoy a quiet time away this is the retreat for you.

Relaxing Comfortable Waterfront Family Dock Suite
Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Luxurious Lakefront Log Home W/Pool & hot tub
Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Stylish Lakefront Group Getaway Sleeps 8
Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Perfect Family Retreat at Lake Marion
Great water front family escape! Enjoy our beach, dock and boat ramp as well as our game room and fully stocked kitchen. We purchased our home is 2006 and began a complete interior and exterior renovation. In 2023 we installed solar panels and an electric vehicle charging station, yet we also have access to the grid for cloudy days and when power demand exceeds what our panels generate. We use a deep well for water. Bring your family for an off-the-grid vacation in our lake home!

Cheerful 3 bedroom home on the lake
Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Relaxation is the plan
Come and relax in this peaceful retreat. A beautiful view of the lake and the sunset from the comfort of the living area or outside on the spacious balcony, a stunning lakefront property offering breathtaking views. This meticulously maintained 2-bedroom, 2-bathroom condo is centrally located off I-95, providing both privacy and convenience. The serene lake views and well-kept interiors create a peaceful retreat for relaxation.

Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss
Introducing your lakeside sanctuary at Lake Marion! This carefully renovated 2 BR, 2 BA condo boasts sweeping lake vistas, fresh LVP flooring, modern lighting, and charming accent walls. Delight in lakeside grilling or venture out for aquatic fun with direct lake access. An hour away from Charleston and Columbia, surrounded by shopping, dining, and golf options, this retreat offers the best of relaxation and adventure.

Cypress shores cottage. Lake Marion Sc
Relax and recharge in this cozy 2BR/1BA home just one row back from Lake Marion. Enjoy an equipped kitchen, bright living area, large streaming TV, and private yard and outdoor seating. Slight water views add to the charm, with marinas, boat landings, and fishing spots just minutes away. Perfect for families, couples, anglers, small groups, or remote workers seeking a peaceful retreat in Eutawville and the Lowcountry.

Big Mama's Lakeside Cottage Lake Marion
Enjoy your coffee from your private screened porch with a view of the lake before settling into any number of lake activities. Fish or swim from your private pier or sit on the shaded pier enjoying a book or doing some work on strong WiFi. Bring your boat and pull kids tubing or find a secluded undeveloped cove less than 15 minutes away to fish or bird watch. Parties and events are not allowed.
Popular amenities for lake access rentals in Santee
Lake access house rentals

Lakefront home with boat ramp and game room

The Cypress House

Lakefront Fishing + Grilling | Home Sweet Home!

Almost Heaven on Lake Marion, SC

SANTEE LAKE MARION GOAT ISLAND AREA NEWLY UPDATED

Fisherman's Dream at Low Falls Landing-Lake Marion

Lake House for Perfect Getaway

Lakefront Lookout
Apartment rentals with lake access

Lake Side Condo Getaway

Lake Marion, SC - 3 Bedroom Deluxe

2Bedroom Condo-Lake Marion!

Lake and pool side vacationing

Come on Down to Goat Island!

Our Place at the Lake.

3-Bedroom Dlx @ Lake Marion Resort

Lakeside Bliss 2BR/2BA Suite Wyndham Lake Marion
Lake access cottage rentals

Three Little Birds- Canal Home

Quiet Waterfront 3 Bedroom on the Lake

Relaxing 2-bedroom cottage, Dorchester, S.C.

A Great Lake house. Near Manning, SC and I-95.
Quick stats about holiday rentals with lake access in Santee

Total holiday rentals
Explore 20 holiday rentals in Santee

Nightly prices starting at
Santee holiday rentals start at € 85 per night before taxes and fees

Verified guest reviews
Over 60 verified reviews to help you choose

Family-friendly holiday rentals
20 properties offer extra space & child-friendly amenities

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wifi availability
20 of Santee holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Santee rentals

4.8 Average rating
Santee stays are highly rated by guests – averaging 4.8 out of 5!
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- Rentals with lake access Orangeburg County
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- Rentals with lake access United States
- Riverbanks Zoo and Garden
- University of South Carolina
- Middleton Place
- Congaree National Park
- Magnolia Plantation & Gardens
- North Charleston Coliseum & Performing Arts Center
- South Carolina State House
- Columbia Museum of Art
- Cypress Gardens
- South Carolina State Museum
- Colonial Life Arena
- Columbia Metropolitan Convention Center
- West Columbia Riverwalk Park and Amphitheater
- Charleston Southern University
- Williams Brice Stadium
- Riverfront Park
- Edventure
- Sesquicentennial State Park
- Soda City Market
- Wannamaker County Park




