Holiday rentals with lake access in Santee

Find and book unique lake access rentals on Airbnb

Top-rated rentals with lake access in Santee

Guests agree: these rentals with lake access are highly rated for location, cleanliness and more.

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Guest favourite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.9 out of 5 average rating, 240 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Superhost
A spacious bedroom features a large bed dressed in white linens, complemented by decorative pillows. Nightstands with soft lamps are placed on either side. Wooden walls provide a rustic backdrop, with two windows adorned by patterned curtains allowing gentle light to filter in.
Bungalow in Summerton
4.78 out of 5 average rating, 125 reviews

The Turtle's Nest

Locally known as the "Turtle's Nest", this getaway will let you be close to all the action. Located on Goat Island, 2nd row back, right off the big water. Boat ramp, boatslip, and restaurant only .3 miles away. Boatslip & ramp included. Remodled to a farmhouse feel, this 3 bedroom, 1 bath has 2 king beds & two singles. Two single beds share the same space as living room. Great retreat after a long day of fishing, or hanging out with family and friends. Be back fast to unwind by the firepit.

Guest favourite
A welcome sign is displayed in front of a light-colored house surrounded by lush green grass. A tree provides shade to the sign, and additional structures are visible in the background. The setting offers a sense of privacy and tranquility.
Cabin in Eutawville
4.87 out of 5 average rating, 116 reviews

The Lake House at Turtle Cove: Cozy relaxing

Nice lake home on a cove that connects to the lake. FIBER HIGH SPEED INTERNET JUST ADDED. JUST ADDED TV's IN BEDROOMS Very quite, private and relaxing. Located 20 minutes from Santee and 1 hour from downtown Charleston. All your streaming services are avalible. This is a great place to disconnect, relax, and enjoy yourself. If you fish , this is on a lake known for great fishing featuring the big blue cat fish. Or if you just want to enjoy a quiet time away this is the retreat for you.

Top guest favourite
A spacious covered deck provides views of the lake through large trees, featuring two striped chaise loungers and a dining table with four chairs. The wooden flooring enhances the outdoor space, inviting relaxation and enjoyment of the serene surroundings.
Guest suite in Eutawville
4.81 out of 5 average rating, 103 reviews

Relaxing Comfortable Waterfront Family Dock Suite

Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Guest favourite
Home in Summerton
4.94 out of 5 average rating, 173 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Guest favourite
A scenic view of the lake is presented, featuring a long dock extending into the calm water. Lush greenery and palm trees frame the foreground, while a faint rainbow appears in the backdrop under a partly cloudy sky.
Home in Santee
4.96 out of 5 average rating, 173 reviews

Stylish Lakefront Group Getaway Sleeps 8

Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Guest favourite
The exterior of the home is showcased, highlighting a charming façade with a mix of brick and siding. Large windows reflect natural light, and the welcoming porch features seating. A landscaped yard and tall trees provide a serene backdrop, complementing the overall inviting atmosphere.
Home in Summerton
4.83 out of 5 average rating, 112 reviews

Perfect Family Retreat at Lake Marion

Great water front family escape! Enjoy our beach, dock and boat ramp as well as our game room and fully stocked kitchen. We purchased our home is 2006 and began a complete interior and exterior renovation. In 2023 we installed solar panels and an electric vehicle charging station, yet we also have access to the grid for cloudy days and when power demand exceeds what our panels generate. We use a deep well for water. Bring your family for an off-the-grid vacation in our lake home!

Top guest favourite
A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.
Home in Summerton
4.99 out of 5 average rating, 128 reviews

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Superhost
An outdoor balcony features a dining table surrounded by four mesh chairs. A ceiling fan is visible above, and the view includes a serene lake framed by trees under a clear blue sky.
Flat in Santee
4.85 out of 5 average rating, 34 reviews

Relaxation is the plan

Come and relax in this peaceful retreat. A beautiful view of the lake and the sunset from the comfort of the living area or outside on the spacious balcony, a stunning lakefront property offering breathtaking views. This meticulously maintained 2-bedroom, 2-bathroom condo is centrally located off I-95, providing both privacy and convenience. The serene lake views and well-kept interiors create a peaceful retreat for relaxation.

Superhost
A spacious living area features a sectional sofa, a coffee table, and an area rug. The dark accent wall is adorned with framed art. A smart TV is mounted above a modern fireplace. A dining table for four is visible in the background, leading to the kitchen.
Apartment in Santee
4.91 out of 5 average rating, 45 reviews

Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss

Introducing your lakeside sanctuary at Lake Marion! This carefully renovated 2 BR, 2 BA condo boasts sweeping lake vistas, fresh LVP flooring, modern lighting, and charming accent walls. Delight in lakeside grilling or venture out for aquatic fun with direct lake access. An hour away from Charleston and Columbia, surrounded by shopping, dining, and golf options, this retreat offers the best of relaxation and adventure.

Superhost
Home in Eutawville
4.76 out of 5 average rating, 17 reviews

Cypress shores cottage. Lake Marion Sc

Relax and recharge in this cozy 2BR/1BA home just one row back from Lake Marion. Enjoy an equipped kitchen, bright living area, large streaming TV, and private yard and outdoor seating. Slight water views add to the charm, with marinas, boat landings, and fishing spots just minutes away. Perfect for families, couples, anglers, small groups, or remote workers seeking a peaceful retreat in Eutawville and the Lowcountry.

Top guest favourite
A serene lake view is presented, featuring a wooden pier extending into calm waters surrounded by lush trees. The vibrant green grass leads to the water's edge, reflecting the clear blue sky above.
Cottage in Manning
5 out of 5 average rating, 27 reviews

Big Mama's Lakeside Cottage Lake Marion

Enjoy your coffee from your private screened porch with a view of the lake before settling into any number of lake activities. Fish or swim from your private pier or sit on the shaded pier enjoying a book or doing some work on strong WiFi. Bring your boat and pull kids tubing or find a secluded undeveloped cove less than 15 minutes away to fish or bird watch. Parties and events are not allowed.

Popular amenities for lake access rentals in Santee

Quick stats about holiday rentals with lake access in Santee

  • Total holiday rentals

    Explore 20 holiday rentals in Santee

  • Nightly prices starting at

    Santee holiday rentals start at € 85 per night before taxes and fees

  • Verified guest reviews

    Over 60 verified reviews to help you choose

  • Family-friendly holiday rentals

    20 properties offer extra space & child-friendly amenities

  • Holiday rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wifi availability

    20 of Santee holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santee rentals

  • 4.8 Average rating

    Santee stays are highly rated by guests – averaging 4.8 out of 5!