Apartment holiday rentals in Santa Cruz de la Sierra

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santa Cruz de la Sierra

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Guest favourite

Apartment in Centro

4.83 out of 5 average rating, 164 reviews

Spacious apartment on the 1st ring.

Departamento de 2 dormitorios con piscina ubicado en zona céntrica. Super confortable, 2 baños (1 en suite). Excelente ubicación: A diez cuadras de la plaza principal, escasos metros del estadio Tahuichi Aguilera, lugares de comer, farmacias, super, lugares de entretenimiento. ¡Aquí tendrás una excelente estadía! 2 bedroom apartment located in a central area on the first ring. Ten blocks from the main square, a few meters from the Tahuichi Aguilera stadium and meters from the urban park.

19–26 Nov

€ 28 per night

Guest favourite

Apartment in Centro

5.0 out of 5 average rating, 9 reviews

Comfortable, central and 24-hour security

Discover your home in the heart of the city! Spacious 1-bedroom apartment, modern amenities, and unbeatable location to explore, work, or immerse yourself in local culture. A blocks away from the main square, museums, restaurants, and more. 60 public transportation lines nearby for your convenience. 24/7 security, mini-super at the building. Spacious and cozy environments with Wi-Fi, 55”TV, pool, equipped kitchen and washing machine. Book now and have a great experience of the city!

6–13 Nov

€ 26 per night

Guest favourite

Apartment in Santa Cruz de la Sierra

5.0 out of 5 average rating, 24 reviews

Comfortable apartment in exclusive area, Edf. Nomad

This place has a strategic location - it will be very easy to plan your visit! Located in the exclusive area of Equipetrol with everything at hand. In the building you have: - Outdoor pool - Enjoy the cruceño heat! - Pool room - games and relax. - Work office - in spacious cowork room. - Paid laundry - travel with everything clean. - Churrasquera for a fee. - Restaurant brewery terrace - - Shopping shops - bikinis - clothes - jewelry and more. - 24-hour security.

5–12 Jun

€ 25 per night

Guest favourite

Apartment in Santa Cruz de la Sierra

4.82 out of 5 average rating, 108 reviews

Apartment in Condominium Buganvillas

We are in one of the most privileged condominiums, safe due to its high control and trained personnel. The entire condominium is surrounded by abundant nature with refined gardens, with walkways and well achieved lighting, giving it the touch of tranquility and guaranteed well-being. Common areas: Pools, hot tubs, courts, jogging circuit and playgrounds. Steps away are the "Feria Expos", supermarkets, pharmacies, laundry, living room and spa and food court.

18–25 Mar

€ 54 per night

Guest favourite

Apartment in Santa Cruz de la Sierra

4.88 out of 5 average rating, 111 reviews

Quiet Studio in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

22–29 Dec

€ 29 per night

Guest favourite

Apartment in Santa Cruz de la Sierra

4.92 out of 5 average rating, 51 reviews

Beautiful studio with pool in Equipetrol

Enjoy the comfort of this quiet, fully equipped single room in full Equipetrol. Very good Wifi. Building with pool, coworking area, games room, among others. Very good location: 100 m from Av. San Martin, very pleasant area for walking and close to restaurants, pubs and offices of large companies. It is located 9 minutes by taxi from the Santa Cruz Exhibition Fair (FEXPO), 12 minutes away by taxi ride from Plaza 24 de Setembre by taxi.

11–18 Dec

€ 27 per night

Guest favourite

Apartment in Santa Cruz de la Sierra

5.0 out of 5 average rating, 23 reviews

Apartment in Cond. Barak II

Relax on this unique and quiet getaway in the North Santa Cruz getaway. Enjoy all the comforts for a pleasant stay, close to restaurants, supermarkets, cafes, pharmacies and more, 5 minutes by vehicle from Mall Las Brisas. Building with pool in terrace and code access. The apartment comes with everything you need for an excellent stay: wifi, Smart TV, equipped kitchen, air conditioners and other amenities that will make you feel at home.

31 Aug – 7 Sep

€ 23 per night

Guest favourite

Apartment in Santa Cruz de la Sierra

4.92 out of 5 average rating, 78 reviews

Magnificent Departamento Zona Exclusive Equipetrol

Spectacular apartment in the most privileged area of Santa Cruz. Also close by shops, luxury restaurants, and shopping malls. Bikes and electric scooters with the Mobi App. Fully furnished and equipped apartment with everything you need for a pleasant stay. Access to Pool with city view, Co-Work, Conference Room, Entertainment Room, poker table, Churrasqueras and outdoor areas with beautiful view of Equipetrol all on the 8th floor.

29 Jul – 5 Aug

€ 29 per night

Guest favourite

Apartment in Santa Cruz de la Sierra

4.92 out of 5 average rating, 85 reviews

Modern Studio with a beautiful view in Equipetrol

We offer you a comfortable stady with everything you may need, in this modern and new place with our top quality service. This place is fully furnished and has a beautiful view. Is located in the best area from Santa Cruz, and also near of fancy restaurants, malls and business area. You can have access to building's social areas like: co-work zone, pool, steakhouse and laundry. (pics)

19–26 Dec

€ 29 per night

Guest favourite

Apartment in Santa Cruz de la Sierra

4.92 out of 5 average rating, 51 reviews

Centrally located apartment in Equipetrol

Central and spacious apartment in Equipetrol, ideal for holidays and/or business. Modern details, fully equipped kitchen, spacious rooms, comfortable dining room, outbuildings with all the amenities needed for a very good stay. Modern and spacious social areas consisting of swimming pool, pool table, and gym. Everything you need for an excellent stay in Santa Cruz de la Sierra.

3–10 Aug

€ 46 per night

Guest favourite

Apartment in Santa Cruz de la Sierra

4.9 out of 5 average rating, 69 reviews

AptComplete 1 Bedroom in Exclusive Condominium

1 Bedroom Apartment located in an exclusive area of the city; strategic accesses to the business center, shopping centers, restaurants, historic center and airport. Ideal for business or vacation guests. Spacious Condominium with more than 2,000m2 of common and recreation areas, 24/7 security and surveillance personnel, safe parking option on the street with little traffic.

15–22 Aug

€ 40 per night

Guest favourite

Apartment in Santa Cruz de la Sierra

4.88 out of 5 average rating, 60 reviews

Excellent Equipetrol Department

This unique place is located in Equipetrol; an exclusive, quiet, and safe area of Santa Cruz. It has all the comforts for a pleasant stay, whether for leisure or work trips (wifi and work area). It is 1 min from Patio Desing, 8 min. Del Ventura Mall and Av. San Martín, where you will find restaurants, cafes, clothing stores, financial institutions, etc.

4–11 Oct

€ 30 per night