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Holiday rentals in North Santee River

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Top-rated holiday rentals in North Santee River

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A welcoming home exterior is displayed, featuring a tidy front yard with seasonal flowers and trees in the background. The spacious white house includes large windows and a covered porch, emphasizing its inviting characteristics.
Home in Georgetown
5 out of 5 average rating, 22 reviews

Luxury/Comfort home 3bedrooms/2 full baths

Unwind in this beautifully designed home, offering the perfect blend of comfort, and Southern charm. Whether you’re visiting for a relaxing getaway, a family vacation, or a business trip, this space has everything you need ✔ Stylish & spacious living areas ✔ Fully equipped kitchen✔ Comfortable bedrooms✔ Fast WiFi & Smart TV✔ Peaceful location, just minutes from historic Georgetown & local attractions.Nestled in the heart of Georgetown, close to scenic waterfront views, charming shops, and dining

Top guest favourite
Home in Pawleys Island
4.94 out of 5 average rating, 185 reviews

Unique New Remodel Close to Beach and Golf

Fully remodeled, the little cabin on the marsh is a 1 BR house with a loft. Inside is almost all wood. The house sits on the marsh water of the Waccamaw river. The neighborhood is a dirt road with a mix of mobile homes and houses. The neighbors are great and have lived on the street for decades. The house is surrounded by live oaks, nature and tidal marsh water in the backyard. Litchfield and Pawleys Island beaches are 5 minutes away. World class golf, restaurants, and grocery stores are near.

Top guest favourite
Home in Georgetown
5 out of 5 average rating, 17 reviews

Porch Paradise in Historic Georgetown, Harborwalk

Step back in time in this charming 19th Century Home in Historic Georgetown, SC. Just a short stroll from the scenic riverfront, this timeless gem blends historic character without sacrificing comfort. The home features iconic double front porches, perfect for morning coffee or evening breezes under the canopy of century-old live oak trees lining a quiet, picturesque street. Just minutes on foot from rich coastal culture, charming shops, waterfront dining, museums, festivals, parks and marina.

Top guest favourite
The living area features a light blue wall, complemented by framed artwork. A bright red loveseat and a dark brown sofa with colorful cushions provide seating. A glass coffee table rests on a textured dark rug, while a wooden cabinet and a television complete the space.
Flat in Georgetown
4.98 out of 5 average rating, 315 reviews

Georgetown Vogue in the Heart of the City

Located on Front St in the heart of historic Georgetown, this 1 BR, 1 Bath, full kitchen, apartment is located on the second floor of a smartly designed, mixed use, Charleston-style building. Surrounded by restaurants, museums, theater, Harborwalk, and shops, this apartment accommodates 2 in a no smoking environment and offers high speed internet, and large screen TV. No pets. Guests enjoy a quiet setting together with 1 free pass per occupant to the Purr & Pour Cat Café. Free parking.

Guest favourite
A serene sunset casts warm hues over the water, with a houseboat moored alongside a covered dock. Silhouetted against the sky, fishing rods stand tall, and tall grasses frame the scene, enhancing the tranquility of this riverside setting.
Home in Georgetown
4.89 out of 5 average rating, 160 reviews

Maggie Jo’s paradise on the river !

Reconnect with nature at this unforgettable escape. Maggie jo is a 1970 completely restore houseboat. She has got a full size refrigerator , gas range ,microwave and toaster oven. Out on the back deck she has a gas grill. The aft berth has 2 full beds that are extremely comfortable. Galley dinette make into bed and the couch in the saloon pulls out also. While on the decks you will see eagles, dolphins , gator or fishing jumping out of the water. I also have 2 tandem kayaks for your use.

Top guest favourite
A wooden dock extends into calm waters, featuring two Adirondack chairs positioned at the end. Surrounding marsh grasses create a natural landscape, and a clear blue sky is visible above, enhancing the serene environment.
Home in Georgetown
4.96 out of 5 average rating, 73 reviews

Dolphin Point: Beautiful bungalow w/ private dock

King Beds, large outdoor space with fire pit, beautiful dock views at sunrise and sunset… names a few of our many amenities - 1,128 Sq Ft Home - Minutes from historic Georgetown/Winyah Bay and near Pawleys Island and the surrounding areas - Extensive parking, large outdoor screened in porch, outdoor swing and shower station, and updated appliances. Permit Number: 00000745 Business License: 12000211 Streaming services: Netflix, Hulu, HBO Max, Youtube TV, Disney+, ESPN+, Prime Video

Superhost
An antique tugboat is anchored on calm waters, showcasing its sleek black hull and bright white cabin. Large windows provide an unobstructed view, while nearby flags flutter gently in the breeze. The surrounding area features a mix of greenery and docks.
Boat in Georgetown
4.75 out of 5 average rating, 36 reviews

Antique Tugboat on the Harborwalk

Welcome aboard this lovingly restored antique tugboat, moored just steps from the storied streets of Georgetown. Once a proud workhorse of American waterways, this vessel now offers a rare opportunity to experience life as it was in 1907—without sacrificing comfort. Let the scent of old pine and briny air greet you each morning as the harbor stirs to life. Cradle a warm mug of coffee as the sun lifts above the horizon, painting the masts and marshes in amber light. Your voyage awaits.

Guest favourite
Home in Pawleys Island
5 out of 5 average rating, 10 reviews

One-of-a-Kind 4BR on 18th Hole

One-of-a-kind stay on the 18th green of Heritage Club in Pawleys Island. This spacious 4BR/4BA home features queen beds, private bathrooms for each room, and lockable doors for added privacy. Every bedroom includes a 55" TV, and the living room boasts (2) 75" TVs. Enjoy stunning golf views, a large dining/card area, and plenty of room to unwind—perfect for golf trips, families, or group getaways. Minutes from the golf course and just a short drive to shopping and public beach access.

Top guest favourite
The entrance of the cabin features a modern black exterior with a circular welcome mat and a stylish door showcasing large glass panes. Potted white flowers add a touch of nature, while an outdoor chair invites relaxation amidst the greenery of surrounding trees.
Farm stay in Georgetown
4.99 out of 5 average rating, 69 reviews

Lo & Billy’s Place a Historic 1940s Newlywed Cabin

This romantic cabin located on our small farm just outside of town in the country offers a history all its own. Lo was Billy’s nickname for Lorene Ella. Lo & Billy got married in the 1950s and lived here. Renovated after meeting Lo and hearing her stories. We pay homage to the rich history of Georgetown and the Southerners that have called Lo & Billy’s Place home. Heavy on coziness & design. Full kitchen; good coffee; & comfy queen bed w/high end linens. The perfect escape.

Guest favourite
A rustic fireplace is framed by a charming brick structure, with flames gently flickering inside. Two soft, gray chairs are positioned nearby, complemented by a small marble side table. Decorative greenery and a vase of flowers enhance the cozy ambiance of the room.
Cabin in Georgetown
5 out of 5 average rating, 8 reviews

#2: The Cottage + Hot Tub + More

The Only Luxury Escape in the Heart of the Santee Delta’s Untouched Beauty! Escape to a private luxury cottage blending historic charm with modern comforts. This historic Cottage offers cozy elegance and sleeps up to seven with two king bedrooms, a loft with a daybed and pull-out twin, plus a private loft bedroom with full bed. Relax in your private garden retreat with a hot tub, and other amazing amenities! Plenty of parking for cars/trucks and trailers including boats!

Top guest favourite
Guest suite in McClellanville
4.96 out of 5 average rating, 151 reviews

Resort @ Kit Hall Pool & Gardens, near Charleston

Centrally located between Myrtle Beach, Mount Pleasant and Charleston SC ( closest beach 36 miles by car. A sanctuary with an amazing freshwater (not chlorine or salt but Ionized)swimming pool, between two national parks, The Francis Marion National Forest & Cape Romain Wildlife Refuge. Near waterways, hiking, cycling trails, fishing, low country dining, historical plantations and more. 2 bedrooms & a screened sleeping porch. 4 beds + library, kitchenette & 2 ba

Guest favourite
Cottage in Georgetown
5 out of 5 average rating, 14 reviews

Poolside Villas @ Winyah Bay Club!

Winyah Bay Club features 17 stylish, individual cottage units, each ideal for large wedding parties, golf enthusiasts, and families. This cottage offers 2 spacious bedrooms (the master has breathtaking water views) and 2.5 baths. The open-plan living room, kitchen, and dining area on the second floor are designed to maximize the stunning waterfront vistas, making every stay memorable and luxurious.

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