
Guest house holiday rentals in La Mesa
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Top-rated guest house rentals in La Mesa
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in La Mesa
Family-friendly guest house rentals

Private Guest House for 2 with Kitchen + Laundry

"Glam Farmhouse dream cottage"🏠🌠

The Happy Family * 2 playhouses near SDSU!

The BEST NEST Clean, peaceful, private, affordable

Casita Daisy: Fully Equipped 1BR Home in San Diego

Cozy Cottage 1/2 mile to North Park close to dtwn

Cosy quiet Guesthouse near SDSU

Mid Century Studio Bungalow Near SDSU
Guest house rentals with a patio

Santorini-Inspired Cottage w/ Hot Tub + Views

La Jolla Oasis: Ocean, City and Fire Works Views

Downtown Cottage Minutes to Gaslamp & Petco Park

Breathtaking Ocean Views-Sunset Cliffs/Ocean Beach

New! Beautiful Private Casita- King Bed & Office

Heart of SD | Zoo Nearby | Private Patio | Central

San Diego Newly Built Private Guesthouse (Sleep 4)

Central studio w/ private outdoor space & parking
Guest house rentals with a washing machine and dryer

Lovely Guesthouse in garden setting

Cozy Detached Casita w/AC & heat

The Golden Hill mosaic "casita"

Hidden Casita with Private Deck & Patio

Modern mountain guest house. Incredible views

New Guest House - North Park

Quaint Craftsman#2- Walkable, Parking, EV Charging

PRIVATE VISTA SUITE/ CENTRAL SAN DIEGO 1BED/1BATH
Quick stats about guest house rentals in La Mesa
Total rentals
80 properties
Nightly prices starting at
€ 43 before taxes and fees
Total number of reviews
5.6K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with a pool
10 properties have a pool
Destinations to explore
- Southern California Holiday rentals
- Los Angeles Holiday rentals
- Stanton Holiday rentals
- Las Vegas Holiday rentals
- Channel Islands of California Holiday rentals
- San Diego Holiday rentals
- Phoenix Holiday rentals
- Palm Springs Holiday rentals
- Scottsdale Holiday rentals
- San Fernando Valley Holiday rentals
- Las Vegas Strip Holiday rentals
- Henderson Holiday rentals
- Pet-friendly rentals La Mesa
- Smoking-friendly rentals La Mesa
- Rentals with beach access La Mesa
- Rentals with a hot tub La Mesa
- Rentals with a beach view La Mesa
- Private suite rentals La Mesa
- Rentals with a firepit La Mesa
- Rentals with outdoor seating La Mesa
- Rentals with an EV charger La Mesa
- Fitness-friendly rentals La Mesa
- Flat rentals La Mesa
- Villa rentals La Mesa
- Rentals with a washing machine and dryer La Mesa
- Rentals with breakfast La Mesa
- Family-friendly rentals La Mesa
- Rentals with a fireplace La Mesa
- Rentals with a patio La Mesa
- House rentals La Mesa
- Rentals with pools La Mesa
- Guest house rentals San Diego County
- Guest house rentals California
- Guest house rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Pacific Beach
- Tijuana Beach
- SeaWorld San Diego
- Coronado Beach
- University of California San Diego
- LEGOLAND California
- San Diego Zoo Safari Park
- Balboa Park
- La Misión Beach
- Oceanside Harbor
- Pechanga Resort Casino
- Coronado Shores Beach
- Black's Beach
- Belmont Park
- Moonlight Beach
- Sesame Place San Diego
- Liberty Station
- Law Street Beach
- Torrey Pines Golf Course
- Santa Monica Beach
- USS Midway Museum