House holiday rentals in La Mesa

An outdoor seating area is equipped with sectional sofas arranged around a fire pit, featuring a grassy lawn surrounded by lush greenery. A large tree provides shade, while a spacious porch is visible in the background, contributing to the serene atmosphere.

4.94 out of 5 average rating, 160 reviews

Family Fun! Game Garage + Big Yard + Free Parking

Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

4.92 out of 5 average rating, 123 reviews

HotTub & 100+ Game Arcade Family Getaway San Diego

Nearby📍 ✈️ San Diego Airport - 20min drive 🦓 San Diego Zoo – 17 min drive 🌸 Balboa Park – 17 min drive 🐬 SeaWorld – 22 min drive 🏙 Gaslamp Quarter – 20 min drive 🏡 Old Town San Diego – 20 min drive 🏖 Mission Beach – 25 min drive ⚾ Petco Park – 20 min drive 🌄 Mount Helix Park (scenic views) – 8 min drive ☕ Best Coffee: Public Square Coffee House (5 min) 🧭 Best Family Activity: San Diego Zoo (17 min) 🛍 Best Shopping: Grossmont Center (5 min) 🌿 Best Nature Spot: Mount Helix Park (8 min)

A contemporary casita is featured with a neatly landscaped front yard and stone pathway leading to the entrance. A garage is visible to the left, and large windows allow natural light to illuminate the welcoming exterior, which is surrounded by lush greenery.

4.9 out of 5 average rating, 140 reviews

Sunnyside Resort Spa, Beach, Zoo, Arcade

SEND US A MESSAGE FOR SPECIAL OFFER! Imagine booking the most memorable experience with your party! Kick back and relax in a safe, stylish casita. Check in contactless and enjoy! Cozy, comfy, and a perfect base for exploring the city. Cook your own meal in the alluring kitchen or enjoy your meal at the cute dining area outside. Great for family's or trips with friends! The entire guest house is is 5 minutes from SDSU, 15 minutes from the beach and 15 minutes from downtown San Diego! Enjoy

A serene bedside scene features a spacious bed topped with crisp white linens. A modern nightstand stands beside it, holding a decorative white vase with greenery and a stylish lamp providing soft light.

4.86 out of 5 average rating, 280 reviews

5 Bed Zen Oasis | Fire Pit, BBQ, Laundry, Parking

Capture the essence of San Diego in our 3 bedroom house hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 10 guests with beautiful outdoors and garden, fire pit table, BBQ grill, FREE laundry, central A/C and heating, 5 comfortable king and queen size beds, plenty of sheets and towels, 4 large HDTVs, Netflix, Max, Hulu, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

A welcoming living area features a spacious beige sectional sofa adorned with patterned throw pillows. Natural light filters through a large window, complemented by soft, flowing curtains. A dark ottoman with decorative details adds a contrasting element to the cozy space.

4.96 out of 5 average rating, 141 reviews

Zen Retreat: 3-Bedroom Oasis near La Mesa Village

Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

A view into a modern living space reveals a sleek kitchen with bar seating and a spacious dining area. Natural light floods the room through large glass doors, showcasing lush greenery outside. A cozy area is completed with a colorful rug beneath and a inviting seating arrangement.

4.94 out of 5 average rating, 249 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

A cozy living area features a sleek sofa adorned with decorative pillows. A stylish coffee table is positioned in front of the seating. A light yellow wall provides a warm backdrop, with a shelf displaying decorative plates and art, illuminated by subtle lighting.

4.9 out of 5 average rating, 204 reviews

Classic Mid-Century Mount Helix Home with Views

Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though, you may not want to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.

A spacious outdoor area features a swimming pool, accompanied by colorful lounge chairs and a large umbrella for shade. A unicorn float is visible in the water, with potted flowers adding a touch of vibrancy. The home's façade offers multiple windows and seating options nearby.

4.99 out of 5 average rating, 204 reviews

Mid-Century Style Family House with Spa

This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.

4.94 out of 5 average rating, 148 reviews

Palm Cottage, San Diego

Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!

A comfortable living area with a gray sofa and patterned accent pillows is highlighted by a ceiling fan. Armchairs in a light blue pattern provide additional seating. A coffee table sits centrally on a light area rug, with natural light entering through the window and reflecting off the walls.

4.92 out of 5 average rating, 230 reviews

Charming La Mesa Home

**Home cleaned and disinfected following COVID-19 guidelines provided by CDC/Airbnb** Charming 3 bed, 1 bath. Feel at home with your own private laundry, full size kitchen, spa like bathroom and private office/workspace. This place is perfect for both work and leisure getaways. Walking distance from stores, shops, restaurants, and parks. 3 minutes from Highways 125, 94, and 8. Centrally located and less than 15 minutes from downtown San Diego.

4.91 out of 5 average rating, 119 reviews

San Diego Oasis: Private Pool & Sunny Escape!

Welcome to our retreat in La Mesa! 🌟 We're passionate about sharing the magic of this place with our guests. Enjoy the comfort and convenience of this 2-bedroom, 2-bathroom home, meticulously remodelled for you. ✨ Get your swimwear, your shopping bags and your adventurous spirit ready to experience the best of the area from our cosy home. 🏡 Your perfect getaway starts here! 🌴🛍️ Booking with us is an unforgettable experience. 🥂✨

4.97 out of 5 average rating, 396 reviews

A spacious backyard is illuminated by string lights, creating a warm ambiance. Lush greenery, including tall palm trees and banana plants, frames the area. A wooden deck provides an outdoor seating space, while comfortable patio furniture is visible nearby. The sky displays soft pastel colors at twilight.

Home in Del Cerro

SDSU Beach Cottage

Welcome to our charming SDSU Beach Cottage! Centrally located in a desirable San Diego neighborhood, you're just 10 minutes from many of the city's top attractions. Steps away, you'll find popular local dining, a wine bar, pub, natural market, pizza shop, nail salon, liquor store, and Einstein Bros. Bagels. Enjoy San Diego's best or unwind in our tropical backyard featuring outdoor games and ping pong. Minimum age to book: 25.

Popular amenities for house rentals in La Mesa

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

A view of the inviting swimming pool surrounded by a spacious patio. Natural rock elements and vibrant landscaping enhance the outdoor area. The multi-level deck is visible, offering seating options and picturesque canyon surroundings under a clear blue sky.

4.89 out of 5 average rating, 218 reviews

The Queen House

A dining area is highlighted by a round wooden table surrounded by six wooden chairs. A cozy blue sofa is positioned nearby, with large glass doors opening to a pool area. Natural light enhances the space, complemented by a modern pendant light overhead.

4.93 out of 5 average rating, 98 reviews

San Diego Oasis- A Retro Retreat w/ King Size Bed!

A private pool is surrounded by a spacious patio, featuring a built-in spa and floating pool accessories. Lounge chairs are arranged by the poolside, while the nearby house is complemented by green shrubbery and playful palm trees. Bright sunlight highlights the inviting blue water.

4.9 out of 5 average rating, 111 reviews

QUIET HOME -3 Bedroom & Den, + POOL, sleep 8 plus

4.96 out of 5 average rating, 222 reviews

A dining space features a round table with four white chairs, complemented by a potted plant. Large glass doors slide open to reveal expansive views of the backyard, pool, and surrounding hills, with soft evening light illuminating the scene.

Home in Spring Valley

Upscale Resort House /Views, Saltwater Pool/Spa !

4.85 out of 5 average rating, 260 reviews

A spacious outdoor area features a clear blue pool surrounded by palm trees. Lounge chairs are positioned nearby, and a shaded table with chairs offers a spot for relaxation. The backyard showcases a privacy fence and ample sunlight.

Home in El Cajon

San Diego Pool | Fire Pit | Sunshine | Sleeps 10

The property features a spacious backyard with a heated pool surrounded by lounge chairs. Palm trees line the perimeter, and soft lighting illuminates the outdoor area during sunset. The two-story house overlooks the pool, creating an inviting atmosphere for relaxation and gatherings.

4.93 out of 5 average rating, 250 reviews

Family Pool Retreat + Gym, Fire Pits, Views (Sleep

4.86 out of 5 average rating, 121 reviews

Entertainers Dream Pool Home

A serene outdoor space showcases a sparkling pool adjacent to a jetted hot tub, with canyon views stretching in the background. A glass fence enhances the vista, and the surrounding landscape features palm trees and gentle hills under a clear blue sky.

4.98 out of 5 average rating, 115 reviews

ModernCoastal I View I Pool ITub

Weekly house rentals

4.98 out of 5 average rating, 103 reviews

A serene outdoor seating area features two cushioned chairs and a small table, overlooking a panoramic view of the landscape. Lush greenery is framed by palm trees, enhancing the tranquil atmosphere under a clear blue sky.

Home in Del Cerro

The Home with The View

An outdoor patio area features a round table with four chairs, all adorned with colorful cushions. A large red umbrella provides shade, and a decorative rug adds vibrancy to the stone surface. Surrounding greenery and blooming plants create a serene environment.

4.98 out of 5 average rating, 341 reviews

Travel Writer's Pad

4.85 out of 5 average rating, 424 reviews

Cozy 4bd Family Home near all SD Attractions!

A spacious living room features a large sectional sofa with orange accent pillows, complemented by a round coffee table. An island with bar stool seating is visible, along with modern kitchen appliances. Natural light enters through the nearby window, highlighting the warm wood tones of the decor.

4.95 out of 5 average rating, 108 reviews

Cozy Mid-Century Charmer | Huge Backyard | Firepit

4.83 out of 5 average rating, 129 reviews

Large Home Heated Pool Spa | Game Room (Sleeps 30)

4.89 out of 5 average rating, 123 reviews

Stylish San Diego Home with Hot Tub Near SDSU

The exterior of a modern two-story home is displayed, featuring solar panels on the roof. Brightly lit outdoor spaces are landscaped with greenery, leading to a cozy seating area near a stylish outdoor fireplace.

4.99 out of 5 average rating, 152 reviews

Newly Built Upscale Home with 5 Bedrooms/6 Baths

An inviting game room is highlighted by a polished pool table, surrounded by warm wooden beams overhead. A modern kitchen area is visible, featuring sleek appliances. Nearby, a laundry area is equipped with stacked machines, creating a functional and comfortable space for relaxation and entertainment.

4.96 out of 5 average rating, 99 reviews

San Diego Retreat ·Jacuzzi + Billiards +Sleeps 12!

Private house rentals

The charming cottage is framed by lush greenery and vibrant landscaping. A wooden bench sits on the patio, inviting relaxation, while the terracotta roof complements the light-colored exterior. Numerous windows and a welcoming entrance provide a glimpse into the bright and airy interior.

4.85 out of 5 average rating, 41 reviews

La Mesa Village Spanish Cottage

4.95 out of 5 average rating, 83 reviews

Downtown La Mesa gem

A welcoming porch area features comfortable outdoor seating, with a sleek coffee table placed between black wicker couches. Potted plants add greenery to the space, while a ceiling fan hangs above. The porch is accessible and provides a view of the surrounding area.

4.92 out of 5 average rating, 59 reviews

Oliver House in La Mesa

4.96 out of 5 average rating, 26 reviews

Sunny La Mesa Home w/ Pool & Spa | Family Friendly

The backyard area features a saltwater pool, surrounded by inviting lounge chairs and palm trees. A patio with umbrellas offers shaded seating, while the upper balcony of the house overlooks the scene. Lush greenery enhances the tranquil ambiance of the outdoor oasis.

4.93 out of 5 average rating, 80 reviews

5br Home with Pool, Hot Tub, BBQ, Putting green

A modern living room features a sleek black sofa set arranged around a low coffee table. A large television mounted above a black stone fireplace provides entertainment. Natural light streams through expansive windows, highlighting views of the surrounding landscape.

4.95 out of 5 average rating, 43 reviews

Panoramic San Diego Views • Fire Pit • Sleeps 9

4.98 out of 5 average rating, 48 reviews

Helix Haven