
House holiday rentals in La Mesa
Find and book unique houses on Airbnb
Quick stats about house rentals in La Mesa

Total holiday rentals
Explore 340 holiday rentals in La Mesa

Nightly prices starting at
La Mesa holiday rentals start at €26 per night before taxes and fees

Verified guest reviews
Over 15,230 verified reviews to help you choose

Family-friendly holiday rentals
220 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 120 rentals that welcome pets

Holiday rentals with a pool
80 properties feature pools

Rentals with dedicated workspaces
220 properties have a dedicated workspace

Wifi availability
340 of La Mesa holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across La Mesa rentals

4.9 Average rating
La Mesa stays are highly rated by guests – averaging 4.9 out of 5!
Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness and more.

Family Fun! Game Garage + Big Yard + Free Parking
Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

Sunnyside Resort Spa, Beach, Zoo, Arcade
SEND US A MESSAGE FOR SPECIAL OFFER! Imagine booking the most memorable experience with your party! Kick back and relax in a safe, stylish casita. Check in contactless and enjoy! Cozy, comfy, and a perfect base for exploring the city. Cook your own meal in the alluring kitchen or enjoy your meal at the cute dining area outside. Great for family's or trips with friends! The entire guest house is is 5 minutes from SDSU, 15 minutes from the beach and 15 minutes from downtown San Diego! Enjoy

Cozy 4bd Family Home near all SD Attractions!
This sunny, 4bd home located on a private cul de sac in Mount Helix. Perfect for both family vacations & business trips. Conveniently situated near freeways & grocery stores. It’s comfortably furnished with a fully equipped kitchen. We have new beach chairs towels & toys! Pac-n-play available, fast Wi-Fi and smart TVs. The home features a quiet, private fenced backyard, BBQ, & covered patio. There’s plenty of room for kids to play! Please note that parties and events are not allowed.

Beautiful Sun-Filled Home w/Amazing Views &Balcony
Located within the prestigious Helix Hills neighborhood is this beautiful, sun-filled home offering views out across La Mesa from the elevated, furnished balcony. Inside you will find 3 beautifully furnished bedrooms, a chic kitchen overlooking the open plan living/dining area with stunning views and a sitting room with an inviting window seat. You'll be just a 5 min drive to the Grossmont & La Mesa Springs Shopping Centers and only 15 mins to the heart of San Diego and all its attractions.

Travel Writer's Pad
Hello, Bonjour, Hola, Ciao, Ni Hao! For the past two decades my career as a travel journalist has taken me around the globe. I’ve stayed at thousands of accommodations, where I learned personal touches create a comfortable home away from home. Certain places I visited offered extra special amenities, such as Green tea at a Japanese Ryokan & chardonnay infused bath salts at a Mexican posada. These kinds of touches are in the home. I welcome you, but no parties or events at the house. Thanks!

Zen Retreat: 3-Bedroom Oasis near La Mesa Village
Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

Classic Mid-Century Mount Helix Home with Views
Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though, you may not want to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.

Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

San Diego Oasis- A Retro Retreat w/ King Size Bed!
Welcome to San Diego Oasis, a retro retreat--a mid-century modern oasis in sunny San Diego! This stylish home combines classic charm with all the modern upgrades you desire. Unwind by the sparkling pool, enjoy a friendly game of air hockey or corn hole, board games or enjoy s'mores around the gas fire pit . The retro retreat is the perfect blend of comfort, convenience, and timeless design. SD's most popular attractions are all within a 20-30 minute drive. Only 20 minutes to the beach!

Mid-Century Style Family House with Spa
This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.

Palm Cottage, San Diego
Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!

SDSU Beach Cottage
Welcome to our charming SDSU Beach Cottage! Centrally located in a desirable San Diego neighborhood, you're just 10 minutes from many of the city's top attractions. Steps away, you'll find popular local dining, a wine bar, pub, natural market, pizza shop, nail salon, liquor store, and Einstein Bros. Bagels. Enjoy San Diego's best or unwind in our tropical backyard featuring outdoor games and ping pong. Minimum age to book: 25.
Popular amenities for house rentals in La Mesa
House rentals with a pool

QUIET HOME -3 Bedroom & Den, + POOL, sleep 8 plus

San Diego Pool | Fire Pit | Sunshine | Sleeps 10

Beautiful 3,000 Sq Ft Tropical Oasis

Entertainers Dream Pool Home

Tropical Oasis: spa, solar heated pool, waterslide

Fletcher Hills luxury, Sunset View, 4 BR, Pool/Spa

San Diego Oasis: Private Pool & Sunny Escape!

*NO TAX*/Heated Pool/Hot Tub/Pizza Oven/Playground
Weekly house rentals

Large Home Heated Pool Spa | Game Room (Sleeps 30)

Charming La Mesa Home

The Home with The View

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

5 Bed Zen Oasis | Fire Pit, BBQ, Laundry, Parking

Newly Built Upscale Home with 5 Bedrooms/6 Baths

San Diego Retreat ·Jacuzzi + Billiards +Sleeps 12!

Beautiful Mid-Century Home on Tree Lined Street!
Private house rentals

Downtown La Mesa gem

Oliver House in La Mesa

Sunny La Mesa Home w/ Pool & Spa | Family Friendly

Newly Updated & Beautiful 5 bed • 3 bath • Hot Tub

*Ocean Views Estate* w/ Pool & Hot Tub

Panoramic San Diego Views • Fire Pit • Sleeps 9

Panoramic Ocean View Retreat - Family Friendly

Surf to Skyline | 6BR Luxury Stay w/ Stunning View
When is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | €159 | €168 | €184 | €181 | €198 | €212 | €215 | €181 | €159 | €162 | €168 | €171 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- San Diego Holiday rentals
- Los Angeles Holiday rentals
- Phoenix Holiday rentals
- Paradise Holiday rentals
- Scottsdale Holiday rentals
- Las Vegas Holiday rentals
- Big Bear Lake Holiday rentals
- Palm Springs Holiday rentals
- Tijuana Holiday rentals
- Joshua Tree Holiday rentals
- Long Beach Holiday rentals
- Santa Barbara Holiday rentals
- Guest house rentals La Mesa
- Rentals with a hot tub La Mesa
- Rentals with pools La Mesa
- Private suite rentals La Mesa
- Family-friendly rentals La Mesa
- Pet-friendly rentals La Mesa
- Rentals with breakfast La Mesa
- Villa rentals La Mesa
- Flat rentals La Mesa
- Rentals with beach access La Mesa
- House rentals San Diego County
- House rentals California
- House rentals United States
- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- Balboa Park
- San Diego State University
- Tijuana Beach
- Pechanga Resort Casino
- Torrey Pines State Beach
- Mission Beach
- Ocean Front Walk
- Las Olas Resort & Spa
- Oceanside City Beach
- Anza-Borrego Desert State Park
- La Misión Beach
- Moonlight State Beach
- Sesame Place San Diego
- Belmont Park





