
House holiday rentals in La Mesa
Find and book unique houses on Airbnb
Quick stats about house rentals in La Mesa

Total holiday rentals
Explore 340 holiday rentals in La Mesa

Nightly prices starting at
La Mesa holiday rentals start at €26 per night before taxes and fees

Verified guest reviews
Over 15,230 verified reviews to help you choose

Family-friendly holiday rentals
220 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 120 rentals that welcome pets

Holiday rentals with a pool
80 properties feature pools

Rentals with dedicated workspaces
220 properties have a dedicated workspace

Wifi availability
340 of La Mesa holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across La Mesa rentals

4.9 Average rating
La Mesa stays are highly rated by guests – averaging 4.9 out of 5!
Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness and more.

Family Fun! Game Garage + Big Yard + Free Parking
Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min
4.94 out of 5 average rating, 163 reviews
Sunnyside Resort Spa, Beach, Zoo, Arcade
SEND US A MESSAGE FOR SPECIAL OFFER! Imagine booking the most memorable experience with your party! Kick back and relax in a safe, stylish casita. Check in contactless and enjoy! Cozy, comfy, and a perfect base for exploring the city. Cook your own meal in the alluring kitchen or enjoy your meal at the cute dining area outside. Great for family's or trips with friends! The entire guest house is is 5 minutes from SDSU, 15 minutes from the beach and 15 minutes from downtown San Diego! Enjoy
4.89 out of 5 average rating, 142 reviews
Travel Writer's Pad
Hello, Bonjour, Hola, Ciao, Ni Hao! For the past two decades my career as a travel journalist has taken me around the globe. I’ve stayed at thousands of accommodations, where I learned personal touches create a comfortable home away from home. Certain places I visited offered extra special amenities, such as Green tea at a Japanese Ryokan & chardonnay infused bath salts at a Mexican posada. These kinds of touches are in the home. I welcome you, but no parties or events at the house. Thanks!
4.98 out of 5 average rating, 341 reviews
Beautiful Sun-Filled Home w/Amazing Views &Balcony
Located within the prestigious Helix Hills neighborhood is this beautiful, sun-filled home offering views out across La Mesa from the elevated, furnished balcony. Inside you will find 3 beautifully furnished bedrooms, a chic kitchen overlooking the open plan living/dining area with stunning views and a sitting room with an inviting window seat. You'll be just a 5 min drive to the Grossmont & La Mesa Springs Shopping Centers and only 15 mins to the heart of San Diego and all its attractions.
4.81 out of 5 average rating, 124 reviews
5 Bed Zen Oasis | Fire Pit, BBQ, Laundry, Parking
Capture the essence of San Diego in our 3 bedroom house hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 10 guests with beautiful outdoors and garden, fire pit table, BBQ grill, FREE laundry, central A/C and heating, 5 comfortable king and queen size beds, plenty of sheets and towels, 4 large HDTVs, Netflix, Max, Hulu, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!
4.85 out of 5 average rating, 281 reviews
Zen Retreat: 3-Bedroom Oasis near La Mesa Village
Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.
4.96 out of 5 average rating, 143 reviews
Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!
4.94 out of 5 average rating, 250 reviews
San Diego Oasis- A Retro Retreat w/ King Size Bed!
Welcome to San Diego Oasis, a retro retreat--a mid-century modern oasis in sunny San Diego! This stylish home combines classic charm with all the modern upgrades you desire. Unwind by the sparkling pool, enjoy a friendly game of air hockey or corn hole, board games or enjoy s'mores around the gas fire pit . The retro retreat is the perfect blend of comfort, convenience, and timeless design. SD's most popular attractions are all within a 20-30 minute drive. Only 20 minutes to the beach!
4.92 out of 5 average rating, 102 reviews
Mid-Century Style Family House with Spa
This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.
4.99 out of 5 average rating, 205 reviews
Palm Cottage, San Diego
Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!
4.94 out of 5 average rating, 149 reviews
QUIET HOME -3 Bedroom & Den, + POOL, sleep 8 plus
Welcome to the La Mesa Pool House! Our cozy house in La Mesa is the perfect place to relax and recharge with the family. This house is walking distance to many great La Mesa eateries such as Terra Restaurant and Surf and Soul. We are also located just 10 minutes away from San Diego State University and we are less than 20 minutes from all major attractions in San Diego: downtown, Little Italy, Zoo, Sea World, beaches and more!
4.9 out of 5 average rating, 114 reviews
SDSU Beach Cottage
Welcome to our charming SDSU Beach Cottage! Centrally located in a desirable San Diego neighborhood, you're just 10 minutes from many of the city's top attractions. Steps away, you'll find popular local dining, a wine bar, pub, natural market, pizza shop, nail salon, liquor store, and Einstein Bros. Bagels. Enjoy San Diego's best or unwind in our tropical backyard featuring outdoor games and ping pong. Minimum age to book: 25.
4.97 out of 5 average rating, 398 reviewsPopular amenities for house rentals in La Mesa
House rentals with a pool

Family Pool Retreat + Gym, Fire Pits, Views (Sleep
4.93 out of 5 average rating, 252 reviews
San Diego Oasis: Private Pool & Sunny Escape!
4.91 out of 5 average rating, 120 reviews
Upscale Resort House /Views, Saltwater Pool/Spa !
4.96 out of 5 average rating, 227 reviews
San Diego Pool | Fire Pit | Sunshine | Sleeps 10
4.85 out of 5 average rating, 263 reviews
Tropical Oasis: spa, solar heated pool, waterslide
4.98 out of 5 average rating, 137 reviews
Entertainers Dream Pool Home
4.86 out of 5 average rating, 123 reviews
Beautiful 3,000 Sq Ft Tropical Oasis
4.96 out of 5 average rating, 178 reviews
Views - Quiet Mt. Helix Home - Pool -Sleeps 11
4.77 out of 5 average rating, 137 reviewsWeekly house rentals

Cozy 4bd Family Home near all SD Attractions!
4.85 out of 5 average rating, 427 reviews
Classic Mid-Century Mount Helix Home with Views
4.9 out of 5 average rating, 206 reviews
SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
4.99 out of 5 average rating, 358 reviews
The Home with The View
4.98 out of 5 average rating, 105 reviews
Charming La Mesa Home
4.92 out of 5 average rating, 231 reviews
Newly Built Upscale Home with 5 Bedrooms/6 Baths
4.99 out of 5 average rating, 155 reviews
Beautiful Mid-Century Home on Tree Lined Street!
4.91 out of 5 average rating, 105 reviews
Stylish San Diego Home with Hot Tub Near SDSU
4.9 out of 5 average rating, 125 reviewsPrivate house rentals

La Mesa Village Spanish Cottage
4.85 out of 5 average rating, 41 reviews
Panoramic San Diego Views • Fire Pit • Sleeps 9
4.95 out of 5 average rating, 44 reviews
Downtown La Mesa gem
4.94 out of 5 average rating, 85 reviews
Sunny La Mesa Home w/ Pool & Spa | Family Friendly
4.96 out of 5 average rating, 28 reviews
*Ocean Views Estate* w/ Pool & Hot Tub
4.99 out of 5 average rating, 73 reviews
Oliver House in La Mesa
4.92 out of 5 average rating, 60 reviews
5br Home with Pool, Hot Tub, BBQ, Putting green
4.93 out of 5 average rating, 81 reviews
Tiny Home with a View
5.0 out of 5 average rating, 55 reviewsWhen is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | €161 | €171 | €186 | €183 | €200 | €215 | €218 | €184 | €161 | €164 | €171 | €173 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- San Diego Holiday rentals
- Los Angeles Holiday rentals
- Phoenix Holiday rentals
- Paradise Holiday rentals
- Scottsdale Holiday rentals
- Las Vegas Holiday rentals
- Big Bear Lake Holiday rentals
- Palm Springs Holiday rentals
- Tijuana Holiday rentals
- Joshua Tree Holiday rentals
- Long Beach Holiday rentals
- Santa Barbara Holiday rentals
- Guest house rentals La Mesa
- Rentals with a hot tub La Mesa
- Rentals with pools La Mesa
- Private suite rentals La Mesa
- Family-friendly rentals La Mesa
- Pet-friendly rentals La Mesa
- Rentals with breakfast La Mesa
- Villa rentals La Mesa
- Flat rentals La Mesa
- Rentals with beach access La Mesa
- House rentals San Diego County
- House rentals California
- House rentals United States
- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- San Diego State University
- Balboa Park
- Tijuana Beach
- Pechanga Resort Casino
- Torrey Pines State Beach
- Mission Beach
- Las Olas Resort & Spa
- Ocean Front Walk
- Anza-Borrego Desert State Park
- Oceanside City Beach
- La Misión Beach
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego





