House holiday rentals in La Mesa

4.91 out of 5 average rating, 111 reviews

HotTub & 100+ Game Arcade Family Getaway San Diego

Nearby📍 ✈️ San Diego Airport - 20min drive 🦓 San Diego Zoo – 17 min drive 🌸 Balboa Park – 17 min drive 🐬 SeaWorld – 22 min drive 🏙 Gaslamp Quarter – 20 min drive 🏡 Old Town San Diego – 20 min drive 🏖 Mission Beach – 25 min drive ⚾ Petco Park – 20 min drive 🌄 Mount Helix Park (scenic views) – 8 min drive ☕ Best Coffee: Public Square Coffee House (5 min) 🧭 Best Family Activity: San Diego Zoo (17 min) 🛍 Best Shopping: Grossmont Center (5 min) 🌿 Best Nature Spot: Mount Helix Park (8 min)

An outdoor seating area is equipped with sectional sofas arranged around a fire pit, featuring a grassy lawn surrounded by lush greenery. A large tree provides shade, while a spacious porch is visible in the background, contributing to the serene atmosphere.

4.94 out of 5 average rating, 154 reviews

Family Fun! Game Garage + Big Yard + Free Parking

Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

The interior of the studio showcases a spacious layout, featuring a king size bed adorned with yellow and white pillows. A dark gray sofa complements the decor, facing a coffee table with a plant. Large glass doors provide a view of the garden and outdoor seating.

4.9 out of 5 average rating, 306 reviews

2 Bed Hidden Oasis | Garden, Laundry, Parking

Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

A contemporary casita is featured with a neatly landscaped front yard and stone pathway leading to the entrance. A garage is visible to the left, and large windows allow natural light to illuminate the welcoming exterior, which is surrounded by lush greenery.

4.9 out of 5 average rating, 132 reviews

Sunnyside Resort Spa, Beach, Zoo, Arcade

SEND US A MESSAGE FOR SPECIAL OFFER! Imagine booking the most memorable experience with your party! Kick back and relax in a safe, stylish casita. Check in contactless and enjoy! Cozy, comfy, and a perfect base for exploring the city. Cook your own meal in the alluring kitchen or enjoy your meal at the cute dining area outside. Great for family's or trips with friends! The entire guest house is is 5 minutes from SDSU, 15 minutes from the beach and 15 minutes from downtown San Diego! Enjoy

4.98 out of 5 average rating, 112 reviews

Home in Serra Mesa

5 Min > Convoy | King Bed | Parking | Private Yard

Experience the beauty of San Diego at prime location, and inviting home 5 min → All freeways 9 mins → Balboa Park 13 mins → Petco Park / Gaslamp Quarter 14 mins → Airport 15 mins → La Jolla Shores Park 16 mins → USS Midway Museum 18 mins → Beach / Coronado 25 mins → Lagoon Trails ⭐️ "One of the best stays in SD" ⭐️ • Extreme Privacy & Fully Fenced • 2 Vehicles Private Parking • Large Patio + BBQ • Stocked Kitchen • Washer + Dryer Add to your wishlist - click ❤️ in the upper-right corner

An inviting living room is filled with natural light streaming through large windows, featuring a spacious sofa and two accent chairs. A wooden coffee table is centered on a neutral rug, while a built-in wooden shelf displays greenery and books. A window seat provides additional seating.

4.81 out of 5 average rating, 116 reviews

Beautiful Sun-Filled Home w/Amazing Views &Balcony

Located within the prestigious Helix Hills neighborhood is this beautiful, sun-filled home offering views out across La Mesa from the elevated, furnished balcony. Inside you will find 3 beautifully furnished bedrooms, a chic kitchen overlooking the open plan living/dining area with stunning views and a sitting room with an inviting window seat. You'll be just a 5 min drive to the Grossmont & La Mesa Springs Shopping Centers and only 15 mins to the heart of San Diego and all its attractions.

A cozy living area features a sleek sofa adorned with decorative pillows. A stylish coffee table is positioned in front of the seating. A light yellow wall provides a warm backdrop, with a shelf displaying decorative plates and art, illuminated by subtle lighting.

4.9 out of 5 average rating, 201 reviews

Classic Mid-Century Mount Helix Home with Views

Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though, you may not want to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.

A view into a modern living space reveals a sleek kitchen with bar seating and a spacious dining area. Natural light floods the room through large glass doors, showcasing lush greenery outside. A cozy area is completed with a colorful rug beneath and a inviting seating arrangement.

4.93 out of 5 average rating, 244 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

A welcoming living area features a spacious beige sectional sofa adorned with patterned throw pillows. Natural light filters through a large window, complemented by soft, flowing curtains. A dark ottoman with decorative details adds a contrasting element to the cozy space.

4.96 out of 5 average rating, 137 reviews

Zen Retreat: 3-Bedroom Oasis near La Mesa Village

Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

A spacious outdoor area features a swimming pool, accompanied by colorful lounge chairs and a large umbrella for shade. A unicorn float is visible in the water, with potted flowers adding a touch of vibrancy. The home's façade offers multiple windows and seating options nearby.

4.99 out of 5 average rating, 200 reviews

Mid-Century Style Family House with Spa

This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.

A modern kitchen and dining area feature sleek cabinetry and stainless steel appliances. An island with bar seating offers additional dining space. A dining table, set for dinner, complements the kitchen's contemporary design. Natural light brightens the space through a nearby window.

4.8 out of 5 average rating, 107 reviews

Welcome New & Improved! Your Home Away from Home

Modern 2BR Oasis with Gourmet Kitchen Enjoy this delightful 2-bedroom, 1-bathroom home featuring a brand-new gourmet kitchen with a dishwasher and shared laundry. Each bedroom offers a spacious closet, iron, and independent split-unit AC for personalized comfort. 🛋️ Perfect for remote work, the space includes high-speed internet and a dedicated workstation. Whether you're cooking a feast or staying productive, this stylish retreat has everything you need! 🍳💻✨

4.94 out of 5 average rating, 144 reviews

Palm Cottage, San Diego

Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!

Popular amenities for house rentals in La Mesa

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

4.94 out of 5 average rating, 152 reviews

An outdoor area features a clear saltwater pool surrounded by elegant lounge chairs. A shaded umbrella stands nearby, and the landscape includes rolling hills and a distant view of the mountains, providing a serene backdrop for relaxation.

Home in El Cajon

Fletcher Hills luxury, Sunset View, 4 BR, Pool/Spa

Double glass doors provide access to the patio, revealing views of a kidney-shaped pool surrounded by a deck. Lush greenery and hills are visible in the background, creating a serene outdoor setting.

4.76 out of 5 average rating, 131 reviews

Views - Quiet Mt. Helix Home - Pool -Sleeps 11

A serene outdoor pool area features a refreshing blue pool surrounded by terracotta tiles. Two lounge chairs are positioned nearby, inviting relaxation. A wooden fence offers privacy while views of the landscape and sky are visible in the background, creating a tranquil atmosphere.

4.81 out of 5 average rating, 102 reviews

The Agave House | Mountain Views & Pool

4.85 out of 5 average rating, 254 reviews

A spacious outdoor area features a clear blue pool surrounded by palm trees. Lounge chairs are positioned nearby, and a shaded table with chairs offers a spot for relaxation. The backyard showcases a privacy fence and ample sunlight.

Home in El Cajon

San Diego Pool | Fire Pit | Sunshine | Sleeps 10

4.88 out of 5 average rating, 232 reviews

A serene outdoor space features a salt-water pool surrounded by a concrete patio and manicured grass. An umbrella provides shade over the poolside area, with lush greenery and mountains visible in the background under a partly cloudy sky.

Home in San Diego

Bright and spacious home with views, pool & spa.

4.94 out of 5 average rating, 103 reviews

A welcoming living area features a leather sofa and a round coffee table, complemented by a modern electric fireplace. Natural light filters through sheer curtains, illuminating decorative vases along the floor. A cozy hanging chair and a potted plant add warmth to the space.

Home in City Heights

Stunning 2BR/2BA| Plunge Pool, AC, Private

5 out of 5 average rating, 104 reviews

A landscaped backyard features a pathway of concrete pavers lined with gravel, leading to a seating area with modern outdoor furniture. To one side, a wooden deck provides elevated space with views of the surrounding area and palm trees, complemented by open sky.

Home in Del Cerro

Modern Hilltop Home: Roomy, Views, Family-Friendly

4.96 out of 5 average rating, 215 reviews

A dining space features a round table with four white chairs, complemented by a potted plant. Large glass doors slide open to reveal expansive views of the backyard, pool, and surrounding hills, with soft evening light illuminating the scene.

Home in Spring Valley

Upscale Resort House /Views, Saltwater Pool/Spa !

Weekly house rentals

4.83 out of 5 average rating, 127 reviews

Large Home Heated Pool Spa | Game Room (Sleeps 30)

A comfortable living area features a light-colored sofa and a sleek wooden coffee table, set on a patterned rug. Natural light fills the space from nearby windows, complemented by soft lighting from stylish lamps and a contemporary chandelier, enhancing the inviting atmosphere.

4.94 out of 5 average rating, 109 reviews

[1,888 SF] Casa De Rosas: Spacious home near SDSU

4.85 out of 5 average rating, 420 reviews

Cozy 4bd Family Home near all SD Attractions!

4.97 out of 5 average rating, 390 reviews

A spacious backyard is illuminated by string lights, creating a warm ambiance. Lush greenery, including tall palm trees and banana plants, frames the area. A wooden deck provides an outdoor seating space, while comfortable patio furniture is visible nearby. The sky displays soft pastel colors at twilight.

Home in Del Cerro

SDSU Beach Cottage

An outdoor seating area features a large sectional sofa in dark wicker with neutral cushions. A glass-top table sits in the center, complemented by an umbrella for shade. The space is enclosed by a wooden fence adorned with greenery and decorative flowers.

4.9 out of 5 average rating, 157 reviews

Cozy 2Bed-Private Parking, Dog Friendly, Big Yard!

A spacious living room features a large sectional sofa with orange accent pillows, complemented by a round coffee table. An island with bar stool seating is visible, along with modern kitchen appliances. Natural light enters through the nearby window, highlighting the warm wood tones of the decor.

4.95 out of 5 average rating, 105 reviews

Cozy Mid-Century Charmer | Huge Backyard | Firepit

A modern living space is highlighted with a comfortable gray sofa adorned with vibrant cushions. A textured golden coffee table is positioned in front of the sofa, topped with a game and a decorative bowl. Natural light floods the area, drawing attention to the art on the walls.

4.97 out of 5 average rating, 65 reviews

Hot Tub, BBQ, Patio, 4 min SDSU, Central San Diego

4.94 out of 5 average rating, 16 reviews

New Mt. Helix Retreat with Views & Patio

Private house rentals

A cozy outdoor seating area features two white Adirondack chairs positioned beside a small round table. The inviting entryway of the tiny home is visible, surrounded by lush greenery and trees, creating a peaceful and refreshing environment.

5 out of 5 average rating, 47 reviews

Tiny Home with a View

5 out of 5 average rating, 38 reviews

Airbnb Luxe: VIEWS, Pool, Fitness, Peloton, Office

4.97 out of 5 average rating, 37 reviews

Traveler's Dream Private Pool Home with Arcade

5 out of 5 average rating, 17 reviews

Bali-Style Tropical Retreat w/sauna & Cabana Bar

4.98 out of 5 average rating, 41 reviews

Helix Haven

4.92 out of 5 average rating, 12 reviews

Couples Retreat | Private, Cozy, Epic Scenic Views

A spacious living area is highlighted by a brown leather sofa and an area rug. Natural light filters through large windows with elegant curtains, revealing a view of the patio. A flat-screen TV is mounted above a sleek entertainment unit, contributing to the modern design.

4.96 out of 5 average rating, 76 reviews

Downtown La Mesa gem