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Holiday rentals in Santo Domingo

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Top-rated holiday rentals in Santo Domingo

Guests agree: these stays are highly rated for location, cleanliness and more.

Guest favourite

Guest house in Pedasi

5.0 out of 5 average rating, 21 reviews

A Remote Paradise in nature - Ocean View

'Tres-Palmas' sea and nature at its best! A remote hideaway on the Pacific Coast of Panama, but yet close enough to nearby towns and entertainment, Tres Palmas is the perfect place for an invigorating holiday. It is more than just a place to stay, we offer our guests personalized attention through fully equipped facilities and services for your comfort and well being. We enjoy getting to know our guests, sharing life stories and greeting you with an authentic smile for an unforgettable stay.

3–10 Jul

€ 134 per night
Guest favourite

Villa in Playa Venao

5.0 out of 5 average rating, 21 reviews

Villa Verde - Luxury&Cozy Villa 1BR #26 BlueVenao

Relax & Calm in a cozy villa with an amazing view of the mountains, located in Playa Venao Beach The villa is fully equipped with 1 Queen size bed and a Sofa bed, High Speed Wi-Fi, Netflix, kitchen cooking tools and appliances like stove, oven, dishwasher, microwave, coffee maker, toaster and blender. Also, you will find a complete laundry with washer and dryer, towels for use inside the Villa, as well as for the pool & beach. Bedrooms come with complete bedding clothes/linens and pillows

3–10 Aug

€ 160 per night
Superhost

Home in Cambutal

5.0 out of 5 average rating, 4 reviews

Casa Concha and Luna Negra

Perched on a gentle bluff above the sun kissed beach of Playa Cambutal, Panama, Casa Concha captures the essence of chic and luxurious living. Built amphitheatrically with direct sea views, this exceptionally designed casa evokes tropical spirit & charm in its elegant environs while ensuring a holiday beyond comparison. From your entire abode observe as the tide rises & falls, exposing a beautiful black volcanic barrier which protects a precious coral reef waiting for your snorkeling pleasure.

23–30 Nov

€ 170 per night

Popular amenities for Santo Domingo holiday rentals

Other great holiday rentals in Santo Domingo

Guest favourite

Flat in Las Escobas del Venado

4.98 out of 5 average rating, 65 reviews

LUXURY Apartment in BLUE Playa Venao D-32

13–20 Aug

€ 192 per night
Superhost

Villa in Las Escobas del Venado

4.95 out of 5 average rating, 21 reviews

Breathtaking Ocean Villa. Casa de Vida

22–29 Jul

€ 538 per night
Guest favourite

Villa in Cañas

5.0 out of 5 average rating, 15 reviews

Residence Denter Tumas

22–29 Apr

€ 463 per night
Guest favourite

Bungalow in Cambutal

4.85 out of 5 average rating, 27 reviews

Wake up in paradise at La Casita!

15–22 Jun

€ 98 per night
Guest favourite

Home in La Villa de Los Santos

4.95 out of 5 average rating, 42 reviews

Amplia casa Villa de los Santos

7–14 May

€ 58 per night
Superhost

Guest house in Cambutal

4.95 out of 5 average rating, 22 reviews

"La Veranera" - private cabin close to the beach.

1–8 Jan

€ 117 per night
Guest favourite

Home in Playa Venao

4.93 out of 5 average rating, 15 reviews

Next to Beach Club: Blue 2 Bedroom Family Villa

12–19 Jan

€ 317 per night
Guest favourite

Holiday home in Chitré

4.97 out of 5 average rating, 32 reviews

CASA EdditA ° Cozy house in Chitre

23–30 Apr

€ 102 per night
Guest favourite

Holiday home in Las Escobas del Venado

4.8 out of 5 average rating, 51 reviews

3 BR Family Surf Villa - Benow in Playa Venao

11–18 Nov

€ 312 per night
Guest favourite

Apartment in Las Escobas del Venado

4.94 out of 5 average rating, 48 reviews

Cool, new condo at Blue Venao

21–28 Feb

€ 190 per night
Superhost

Flat in El Ciruelo

5.0 out of 5 average rating, 4 reviews

Ocean front paradise with private tropical vibe

30 Nov – 7 Dec

€ 87 per night
Guest favourite

Flat in Las Escobas del Venado

4.91 out of 5 average rating, 22 reviews

Beautiful APT in blue venao

18–25 May

€ 176 per night

Destinations to explore