
Holiday rentals in Santa Cruz
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Top-rated holiday rentals in Santa Cruz
Guests agree: these stays are highly rated for location, cleanliness and more.

Beach House-Amazing Pool & Jacuzzi & Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Mountain Retreat: Peaceful & Private Escape
Escape to tranquility in our beautiful rural retreat near Laguna de San Carlos, Panama. Nestled on a private hectare of lush land, this cozy two-bedroom, two-bath house boasts an open terrace with breathtaking views of the San Carlos mountains. Whether basking in summer sun or enveloped in clouds during the rainy season, you’ll find peace and beauty here. Just a 30-minute drive to Coronado and the stunning beaches of Panama Oeste, it’s the perfect sanctuary for your getaway.

Buenavista Cabin by Casa Amaya
Casa Amaya is a cabin complex located one hour from the capital city, in Chicá de Chame, with pleasant temperatures between 18 and 24 degrees, where you can get in touch with nature and relax with your partner, friends or family. Other cabins: https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/panoramabycasaamaya https://www.airbnb.com/h/horizontebycasaamaya We have an electric generator in case of outages.

Summer House
Take the whole family to this fantastic place with many areas to have fun. Close to all the amenities of Coronado, a few minutes from beaches, San Carlos lagoon and just an hour and a half from the city. The PH features a PH pool and a private one, in a quiet and spacious area. You will find 4 supermarkets, pharmacies, private hospital (emergency). Close to country activities, beaches, mountains, lake. It has in a gazebo with all amenities. The place is safe and complete.

Cabaña de montaña con piscina privada
Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and with spectacular views, here you can breathe pure air and gaze at the stars. ✔️ Great for couples, families or adventurers. Nearby ✔️ trails, rivers and viewpoints. ✔️ Comfortable and equipped spaces for your comfort. - Capacity of 4 people - Possibility of having 1 double bed and 2 singles or 4 single beds - Discount from two nights

Nice house with pool steps to the beach
Relax with the whole family in our Rincon de Flavio, a quiet place to stay for the weekend or as long as you need. Three bedrooms with two bathrooms. Fully equipped and decorated in a tropical style. WE NOW HAVE AIR CONDITIONING IN ALL THE ROOMS. With everything you need to enjoy and relax. A 5-minute walk to Coronado Beach and close to restaurants and supermarkets. Large garden, ping pong, swimming pool and comfortable patio with barbecue.

Casa Campestre Los Macos, El Valle de Anton
🏡 Welcome to Casa Campestre Los Macos, a cozy refuge located in the green heart of El Valle de Antón, inside an extinct volcanic crater, the largest inhabited in the world. It is a total rest experience, in a safe and quiet area, ideal for lovers of nature, silence and pure air. You will wake up to the singing of the birds, enjoy a cup of coffee in the garden and spend family afternoons in a fully equipped house.

B31-Tropical beach paradise, 2R/2B condo, w/pool
Disconnect for a few days from the routine. Have fun with your partner or family in our apartment in Punta Barco Viejo, we have everything you need to be comfortable and have fun in one of the most exclusive areas of the area. We have everything nearby for your best convenience, restaurants, banks, supermarkets ... I´ll deliver a personalized 5 stars attention. Oh and of course, the BEACH 5min by car!

Casa Buena Vista
The house is newly built within walking distance to the lookout in the Altos De Campana National Park only 45 minutes from Panama City. With absolutely stunning views it sleeps 4 to make your stay a relaxing, tranquil experience. Bring your own cooler, cook for yourself in a full complete kitchen if you like and enjoy your drinks by the pool.

Fabuloso Apto de playa-Ph Royal Palm-Gorgona
FIRST LINE TO THE SEA WITH DIRECT ACCESS TO THE BEACH FROM THE PH POOLS. Fabulous BEACH APARTMENT, Beach Front Unit, comfortable, unique and to relax with the family, it has 4 incredible swimming pools, jacuzzi, sauna, sports courts, board games and access to the beach and restaurant service, coming is not wanting to leave ever

Mountain cabin in Altos del María
The cabin in Altos del María is located in the heart of the mountain, with beautiful landscapes, trees, animals, monkeys, birds, just minutes from picnic areas, outdoor games, river, waterfall, trails and viewpoints. Escape into nature! Close to everything, away from the daily grind!

Walk through the Clouds
Relax on this unique and quiet getaway just an hour and an half from the city. Every nook of this magical place was meticulously designed to provide perfect escape to couples seeking intimacy, serenity, and unforgettable moments together.
Popular amenities for Santa Cruz holiday rentals
Other great holiday rentals in Santa Cruz

Altos del Maria: Portazul - a Mountain Retreat

Beautiful Casita-Paradise in Panama, New Gorgona

La Casita Encantada #3 by AcoModo

house with 3 bedrooms and a pool

CasAna

5 minutes from Valle I Domo No. 6

Escape the city! Cozy climate and home.

Los Domos Panama, Domo Fuego, Glamping en Altura.
Destinations to explore
- Panama City Holiday rentals
- San Andrés Holiday rentals
- Puerto Viejo de Talamanca Holiday rentals
- Uvita Holiday rentals
- Boquete Holiday rentals
- Quepos Holiday rentals
- Coveñas Holiday rentals
- Playa Blanca Holiday rentals
- Ancón Holiday rentals
- Bahía Ballena Holiday rentals
- Limón Holiday rentals
- Valle de Antón Holiday rentals




