Guest house holiday rentals in San Diego
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in San Diego
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in San Diego
Family-friendly guest house rentals
Guest house in San Diego
4.97 out of 5 average rating, 506 reviewsCentral & Serene Secret Garden Guesthouse
15–22 Oct
Guest house in San Diego
4.91 out of 5 average rating, 355 reviewsLa Casita - Fully Updated Casita in Mission Hills
9–16 Sep
Guest house in Chula Vista
4.95 out of 5 average rating, 475 reviewsPrivate Casita in Great Eastlake Neighborhood
24 Sep – 1 Oct
Guest house in San Diego
4.91 out of 5 average rating, 379 reviewsNorth Park Cottage
15–22 Apr
Guest house in San Diego
4.97 out of 5 average rating, 291 reviewsPrivate Guest House with a View
6–13 Aug
Guest house in San Diego
4.84 out of 5 average rating, 315 reviewsPacific Beach Guest House With Garage and A/C
14–21 Dec
Guest house in San Diego
4.96 out of 5 average rating, 211 reviewsNorth Park, San Diego's Best At Your Doorstep
3–10 Jun
Guest house in San Diego
4.94 out of 5 average rating, 332 reviewsThe BEST NEST Clean, peaceful, private, affordable
3–10 Nov
Guest house rentals with a patio
Guest house in San Diego
5.0 out of 5 average rating, 106 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
22–29 Oct
Guest house in San Diego
4.98 out of 5 average rating, 123 reviewsPrivate Studio Cottage with Outdoor Patio
11–18 Dec
Guest house in San Diego
4.93 out of 5 average rating, 147 reviewsCentral studio w/ private outdoor space & parking
13–20 Jan
Guest house in Oceanside
4.94 out of 5 average rating, 154 reviewsDetached, Private Cottage! Fenced, PET friendly!
22 Feb – 1 Mar
Guest house in La Mesa
4.98 out of 5 average rating, 249 reviewsLa Mesa Suite
17–24 Mar
Guest house in San Diego
4.99 out of 5 average rating, 151 reviewsAdorable cottage in Talmadge
15–22 Apr
Guest house in La Mesa
4.99 out of 5 average rating, 166 reviewsSDCannaBnB #1 *420 *parking *dog-friendly *hot tub
10–17 Jul
Guest house in San Diego
4.99 out of 5 average rating, 138 reviewsMission Hills-Entire Guest House-Center of it All
20–25 Jul
Guest house rentals with a washing machine and dryer
Guest house in San Diego
4.96 out of 5 average rating, 117 reviews1BR Casita in the Heart of Kensington!
3–10 Sep
Guest house in Pacific Beach
4.92 out of 5 average rating, 170 reviewsSparkling Clean Plush Studio w/Private Patio & AC
16–23 May
Guest house in San Diego
4.91 out of 5 average rating, 190 reviewsSTUNNING Casita with a View!!
14–21 Oct
Guest house in San Diego
4.99 out of 5 average rating, 131 reviewsCarrie’s North Park Casita, in Heart of San Diego
6–13 Oct
Guest house in La Mesa
4.99 out of 5 average rating, 132 reviewsStunning Guest House 15 min. from Zoo, Downtown
16–23 Oct
Guest house in San Diego
4.98 out of 5 average rating, 117 reviewsCasita Hermosa - Close to everything in San Diego
23–30 Nov
Guest house in San Diego
4.97 out of 5 average rating, 327 reviewsPrivate Guesthouse with Bay View Deck
21–28 May
Guest house in San Diego
4.92 out of 5 average rating, 526 reviewsThe Best Cottage in North Park!
23–30 Jun
Quick stats about guest house rentals in San Diego
Total rentals
980 properties
Rentals with dedicated workspaces
530 properties have a dedicated workspace
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
240 properties allow pets
Family-friendly rentals
140 properties are a good fit for families
Total number of reviews
101K reviews
Destinations to explore
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