Mansion holiday rentals in Panama
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Top-rated mansion rentals in Panama
Guests agree: these mansions are highly rated for location, cleanliness and more.
Holiday rentals for every style
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Popular amenities for Panama mansion rentals
Luxury mansion rentals
Villa in Panamá
5.0 out of 5 average rating, 30 reviewsBreathtaking Views Mansion w/King Beds
1–8 Dec
Home in Río Hato
4.95 out of 5 average rating, 75 reviewsSpectacular beachfront house in Buenaventura!
10–17 Jul
Villa in Buenaventura, El Chirú
4.85 out of 5 average rating, 39 reviewsLake House | Pool | King Beds | Next to Beach Club
9–16 Nov
Villa in Playa Venao
4.98 out of 5 average rating, 61 reviewsCasa Aqua: Amazing beach front house - Playa Venao
1–8 Apr
Home in Panamá
5.0 out of 5 average rating, 5 reviewsUnique 4 room house - direct access to the beach
11–18 Mar
Apartment in Maria Chiquita
5.0 out of 5 average rating, 17 reviewsPlaya Escondida Lux Beachfront Haven:Oceanview Apt
31 Dec – 7 Jan
Flat in Maria Chiquita
4.95 out of 5 average rating, 20 reviewsPenthouse in Playa Escondida 4 bedrooms
10–17 Jan
Villa in Bejuco
4.96 out of 5 average rating, 78 reviewsBeach house in Punta Chame, Villa frente al mar
19–26 Jul
Pet-friendly mansion rentals
Home in Playa Bluff
5.0 out of 5 average rating, 15 reviewsJungle House 100m from the beach
24 Apr – 1 May
Cottage in Altos del Maria
4.93 out of 5 average rating, 96 reviewsCabin with Spectacular Mountain View
20–27 Jun
Home in Gamboa
4.86 out of 5 average rating, 88 reviewsBirdHouse@ Gamboa Panamá Canal
4–11 Aug
Villa in Portobelo
5.0 out of 5 average rating, 42 reviewsEntire Villa with pool in front of beach!
11–18 Apr
Villa in Bocas del Toro
5.0 out of 5 average rating, 56 reviewsCasa del Mar - eco aqua villa
24 Nov – 1 Dec
Flat in San Carlos District
4.99 out of 5 average rating, 78 reviewsAmazing Oceanfront apartment in San Carlos
15–22 Nov
Apartment in San Carlos District
5.0 out of 5 average rating, 36 reviewsPunta Caelo Beach Front View
3–10 Oct
Villa in Costa Esmeralda
4.97 out of 5 average rating, 68 reviews#1 Villa with pool, jacuzzi, pool table, ping pong.
13–20 Jan
Mansion rentals with a pool
Villa in Río Hato
5.0 out of 5 average rating, 38 reviewsLuxury 4BR Villa + Guesthouse & Pool @Buenaventura
30 Jun – 7 Jul
Flat in Maria Chiquita
4.96 out of 5 average rating, 57 reviewsSpacious 4Br Beachside Getaway at Playa Escondida
19–26 Jul
Flat in Río Hato
5.0 out of 5 average rating, 18 reviews4 Bedroom Private Pool Paradise in Buenaventura
7–14 Jun
Home in Cacique
5.0 out of 5 average rating, 18 reviewsEl Paraiso
15–22 Nov
Home in Provincia de Panamá Oeste
4.88 out of 5 average rating, 16 reviewsLuxurious beach front home in Veracruz
13–20 Oct
Flat in María Chiquita
4.94 out of 5 average rating, 64 reviewsPlaya Escondida Resort & Marina
15–22 Oct
Home in Pedasí
4.83 out of 5 average rating, 6 reviewsOcean View From The Jungle!
15–22 Oct
Flat in Panama City
5.0 out of 5 average rating, 20 reviews24o Penthouse Unique Design 2 Balconies Oceanview
2–9 Apr
Destinations to explore
- Rentals with a firepit Panama
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