
Mansion holiday rentals in Panama
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Panama
Guests agree: these mansions are highly rated for location, cleanliness and more.

Spacious, Over the Water Home with Plunge Pool
Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.

Spacious 4Br Beachside Getaway at Playa Escondida
Escape to Playa Escondida Resort & Marina for the ultimate luxury getaway. Our 4Br beachfront apartment is ideal for families and friends seeking relaxation in the Caribbean Sea. Indulge in plush rooms, white sand beaches, and unforgettable sunsets. Our fully equipped apartment provides everything you need for an exceptional stay, and our unparalleled service ensures you'll never want to leave. Best of all, it's just an hour away from Panama City. Book now for a truly unforgettable experience.

San Blas islands, Tubasenik cultural getaway
Immerse yourself in the stunning beauty of Guna Yala, a paradise of crystal-clear waters and white-sand beaches. Explore secluded islands, relax under swaying palms, or snorkel vibrant coral reefs teeming with marine life. This experience goes beyond typical tourism—it’s a journey into the heart of the Guna culture, an indigenous community that cherishes its ancient traditions and deep connection to nature. Discover exclusive gems of the archipelago and make your adventure truly unforgettable

OceanView-Rooftop Jacuzzi&Pool | Concierge Service
Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 8.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base rate covers up to 4 guests, with a $40 charge per additional person, per night.

5A - Boutique Apartment ! High end furnished! 4BR
This stylish place to stay is perfect for group trips, breathtaking furniture, the green and natural lighting will definitely make this stay a great one! We have many apartments in the same building, in case the entire date you would like to stay is not available, contact us and we will gladly organize your stay! Sorry for the inconvenience if you write us on Friday’s past 5pm our time and on Saturday’s we will reply on Saturday night around 8pm our time best regards!.!

Mountain retreat
Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Tropical Haven with Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Spacious Vacation Home in a Tourist Area
Cozy & comfy villa with great illumination and natural ventilation located in the Playa Blanca Beach & Lagoon complex in Rio Hato, Cocle just 10 minutes away from Scarlett Martinez International Airport and 90 minutes from Panama City. Playa Blanca is an exclusive tourist residential beach complex with villas, apartments, big lush green areas, the largest pool in Central America, beach club, Playa Blanca Hotel Resort and much more.

Rustic family mountain home - 5 min walk to town!
Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.

Exclusive apartment steps from the sea in Puntarena
Enjoy this beautiful and spacious apartment, which is located in Puntarena Ocean Village. Steps to the beach and golf course. Here you will also find boutiques, restaurants, a playground and the Puntarena Beach Club, a beachfront club that has a restaurant, a swimming pool and a pool bar. You can also enjoy all the recreational areas within the Buenaventura complex.

#1 Villa with a swimming pool, jacuzzi, pool table, and ping pong.
Spectacular villa a few minutes from the beach by car, super spacious, ideal to share with family, friends or corporate meetings. The property is full of surprises and with many things to do including its swimming pool, jacuzzi, pool table, ping pong table, domino table, hammocks, large green areas, gas BBQ, variety of board games and a fully equipped kitchen.

Modern | Steps to Beach Club & Shops | Sleeps 10
★ A Proper Rents Experience ★ • Beautiful design • Excellent location • Steps to the La Mansa Beach Club! • Spacious & luxurious • Luxury Bedding • 75 inches TV • Beautiful views! • Half a block from restaurants & convenience store! • Fully equipped • High speed internet • Buenaventura, best luxury beach resort in Panama
Popular amenities for Panama mansion rentals
Luxury mansion rentals

Villa Solara 5 - Luxury 5 Bedroom Pool Villa

Playa Escondida with sea and mountain views

Hacienda La Perezosa in Cerro Azul

Ocean, BBQ & marina - Playa Escondida Resort

Villa Papagayo, Morrillo Beach, Veraguas

Modern Luxury Beach Front House in Coronado

Opulent 4 bedroom Townhouse

Seahouse Bed & Breakfast Beach House with Pool
Pet-friendly mansion rentals

Welcome to our house in Playa Corona

Charming house with beach access

Buenaventura beach condo with private pool

Wonderful House with Terrace and Ocean View

BirdHouse@ Gamboa Panamá Canal

Costa Blanca Beach & Golf Villa by Decameron

Villa Santorini | White Beach

Cerro Azul, Casa de Campo with Climate Pool.
Mansion rentals with a pool

Private Beachfront Getaway

Laguna Fun and Sun: Your Escape Awaits

Playa Escondida Lux Beachfront Haven:Oceanview Apt

Stylish & Quiet ~ Breathtaking Laguna Views ~Pool

Nice duplex house with a swimming pool.

New Jewel in Playa Escondida

Buenaventura | Luxury Beach Apartment | Panama

Beach apartment in BUENAVENTURA
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