
Boutique hotel holiday rentals in Panama
Find and book unique boutique hotel rentals on Airbnb
Top-rated boutique hotel rentals in Panama
Guests agree: these boutique hotel rentals are highly rated for location, cleanliness and more.

Villa Alejandro - Tastefully Furnished Room
Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix

Treetop views of the Pacific in a boutique cabaña
No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Casa Florecer- bungalow at the edge of the sea
Welcome to Casa Florecer, a bungalow at the edge of the sea. Your space is simple and elegant. A studio apartment with plenty of room to enjoy a quiet & peaceful time on the island. The bungalow boasts a screened in porch, gorgeous views, and pristine coral reef for your front yard. All stays include a locally sourced vegetarian breakfast served in our over the water eatery, Juntos. For fun closer to home: we have snorkel gear, paddle boards, and yoga mats available for your enjoyment.

Villa Coco Family Room
Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.

Morro Room - Second Floor, Peaceful location
Morro Room is a peaceful, quiet, 2 person, second floor room in the beautiful El Sitio Hotel. You will be steps away from the sand, listening to the trees sway and the birds sing. Morro has a comfortable queen bed, a clean, Moroccan style decor and a mini fridge to keep your personal beverages cold. The bathroom has hot/cold water where you can rinse off the salt and sand from your day in the sun. *A 10% tax will be collected as Airbnb does not collect tax on behalf of the host.*

Deluxe King Ocean View @ Villa Marina Playa Venao
Amamos el océano tanto como tú. Por eso hemos creado el lugar perfecto para que disfrutes de las olas y de todo lo que el Pacífico panameño tiene para ti en las playas de Pedasí. Villa Marina Lodge es un lugar único en su categoría. Ubicado en Playa Venao, un paraíso internacional del surf, ofrece habitaciones cómodas y amenidades de primera para que tu viaje a la playa sea siempre una experiencia especial. Un lodge, a diferencia de un resort, es más relajado, casual y acogedor.

Andy 1, habitación en casa con acceso a la playa
La habitación Andy 1 está ubicada en un altillo al que se accede por escaleras desde el primer piso de la casa barco. La habitación tiene capacidad para tres personas, cuenta con una cama queen y una sencilla. Dispone de su propio baño privado en la habitación, un escritorio, una televisión, y cuenta con aire acondicionado y acceso a internet. Los huéspedes de esta habitación tienen acceso a una cocina ubicada dentro del lote, a corta distancia de la casa barco.

Habitaciones privadas Sofia's B&B Hostal Boutique
Alojamiento tipo hostal boutique, contamos con 7 cómodas habitaciones privadas con baño, para una capacidad total de 18 huéspedes. La tarifa mostrada por Airbnb para tu reserva distribuye 2 huéspedes por habitación, es decir, los huéspedes deberan compartir camas y/o habitaciones. Si requieres una distribución especial de habitaciones para tu grupo, contacta primero con el anfitrión, ya que la tarifa podría variar.

B) Beach, surf and Relax with King size bed
Manglar Lodge is a small beach Hotel located at El Palmar beach on the Pacific coast on the town of San Carlos, If you like nature and comfort, you'll enjoy your stay at Manglar Lodge We are small beach hotel that offers the visitor four cozy and clean rooms, WiFi, restaurant (open form 8.30am until 8pm) with great food and a great selection of craft beer and The Room is on a 1 floor you have to walk up the stairs

Boutique Inn_The Hill 2_Private Entry_Tripple_+16
The Hill Panama, our Boutique Inn Adult Only (16+) is proud to be featured on Architectural Digest Magazine, located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 2 was designed as a boutique hotel room with separated private entry and communal kitchen.

Suite medievale natura & arte
La Corte del Re é una struttura turistica composta da un insieme di suite con tematica medievale (arte macabra) immerse nel bosco dove arte e natura si fondono nel cuore del Valle di Anton. A pochi passi dal centro sono dotate di tutti i confort e contano con un parco, piscina, lago con carpe Koi e parcheggio. Sono suite e pertanto non dispongono di una cucina.

Corcho rooms #2 - king room with balconies
Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.
Popular amenities for boutique hotel rentals in Panama
Family-friendly boutique hotel rentals

Rancho Cabaña- Private Porch, Loft, 1 min to beach

Family & Group Bungalow

Villa Coco King Room

Olas Room - Quiet, Second Floor w/ Queen bed

Beautiful loft #5 - kingsize bed

Agradecer: Surf lover's dream

Yellow Room for 4 at Casa Lassini - Oceanfront!

Amanecer : Delicious Included Breakfast
Boutique hotel rentals with a patio

Charming 1-Bedroom Beachfront Hotel With Pool

Suite Room in the ORHO Hotel

Tranquil Ocean View Cottage At Seagull Cove Resort

Eshel Panama Suites, Atlantic suite 04

Over the Sea Turtle Mini Cabin with Veranda

Pool side, Family suite, two bedroom one bath.

Boutique Inn_The Hill 1_Private Entry_Sea View_16+

Habitación Standard - Hotel El Huésped
Other boutique hotel holiday rentals

Brisa - Ocean Views, Calm Vibes, King/Twin beds

Ciel Y Miel, Hotel boutique en la costa caribe

Palmas Room - Tranquil Space with King Bed

La Residencia - Habitacion Colibri

Sol Suite - Large room, King bed, Ocean Views

Luna Room - Peaceful and Economical, two twin beds

Private Queen Room 2 at Vida Lotus Retreat & Spa

Boutique Inn_The Hill 3_Private Entry_Sea View_16+
Destinations to explore
- Waterfront rentals Panama
- Bed and breakfasts Panama
- Treehouse rentals Panama
- Nature eco lodge rentals Panama
- Rentals with an accessible-height bed Panama
- Aparthotel rentals Panama
- Hotel rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with beach access Panama
- Tent rentals Panama
- Beach house rentals Panama
- Pet-friendly rentals Panama
- Rentals with a firepit Panama
- Family-friendly rentals Panama
- Smoking-friendly rentals Panama
- Island rentals Panama
- Lakehouse rentals Panama
- Boat rentals Panama
- Cottage rentals Panama
- Flat rentals Panama
- Tiny house rentals Panama
- Bungalow rentals Panama
- Townhouse rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Apartment rentals Panama
- Villa rentals Panama
- Rentals with breakfast Panama
- Guest house rentals Panama
- Rentals with a washing machine and dryer Panama
- Rentals with a sauna Panama
- House rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Chalet rentals Panama
- Rentals with a patio Panama
- Rentals with a cinema Panama
- Rentals with a hot tub Panama
- Rentals with a fireplace Panama
- Container rentals Panama
- Loft rentals Panama
- Fitness-friendly rentals Panama
- Rentals with lake access Panama
- Farm stay rentals Panama
- Dome rentals Panama
- Rentals with pools Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama