Holiday rentals in Osborn Medical Center, Phoenix

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Top-rated holiday rentals in Osborn Medical Center, Phoenix

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A historic guesthouse is framed by a mix of stone and soft greenery. The outdoor area features a stone pathway, bordered by low shrubs, leading to a covered seating area under a wooden gazebo. Sunlight fills the scene, highlighting the inviting residence.
Guest house in Encanto
4.96 out of 5 average rating, 194 reviews

Best Little Guesthouse in Melrose !

Historic guesthouse in the heart of the Melrose District! EV charger! Walking distance to restaurants, bars, coffee shops, the famous Melrose Vintage shops, grocery stores, LA Fitness and more! Want to head downtown to Chase Field, Talking Stick Arena for a game or a show? Campbell Street Light Rail station is only five short blocks away! No need for a car, you can take the Light Rail from Sky Harbor International Airport, save your money for entertainment! Off street parking if you have a car!

Guest favourite
An inviting outdoor area is illuminated by soft lighting, surrounded by lush palm trees. A rectangular lap pool reflects the evening sky, accompanied by spacious green lawns and comfortable lounge chairs. The scene evokes a sense of tranquility and relaxation in a private resort-like setting.
Guest suite in Encanto
4.97 out of 5 average rating, 273 reviews

Clothing Optional Love Shack 2 Hot Tub & Pool

Nude art. Intimate room with private entrance. Palm lined st in Central Phx. Very safe. Close to restaurants, groceries, light rail and arts. Luxury king bed w/sexyprivate full bath, dresser, TV and mini split A/C and heat. Organic linens. Breakfast items. Nude/clothing opt. large, private, resort yard for sun bathing with lap pool, nude hot tub and couples outdoor rain shower. Soap up. Perfect for first/full time nudists. We have two rooms to rent + Clothing Optional Love shack. Massages avail

Top guest favourite
The interior space features an open layout with a cozy sitting area, including a brown couch adorned with white pillows, and a coffee table. The kitchenette is equipped with a refrigerator and modern cabinetry. Natural light enters through large windows, enhancing the warm ambiance.
Guest house in Encanto
4.98 out of 5 average rating, 110 reviews

Spacious Midtown guesthouse with full privacy

Welcome to your private casita (tiny home) in the heart of Midtown. Located right across the street from Starbucks, Buffalo Exchange, and the famous Taco Guild, relax comfortably with vaulted ceilings, a spacious layout, outdoor patio, and a quiet bedroom with a Queen-size bed — perfect for solo travelers or couples. Plus, the Light Rail station is walkable, which goes to Uptown, Downtown, the airport, Tempe, and Mesa. You are only: 7 mins to Downtown 9 mins to the Airport 15 mins to Scottsdale

Superhost
A welcoming living area features two brown leather sofas positioned around a vibrant area rug. A coffee table is centered between them, and a television is mounted on a green accent wall. A potted plant adds a touch of greenery, enhancing the space's warmth.
Apartment in Encanto
4.9 out of 5 average rating, 174 reviews

The Beverly Bungalow 1BR/BA in the 🖤 of Phoenix

Relax & unwind at our mid-century bungalow in the heart of Phoenix. This 1BR/1BA condo will comfortably sleep 2 (up to 4 using an air mattress). Our condo is complete with a full kitchen, cozy living room & dedicated work space for the WFH professional. Also included is a shared pool/hot tub to cool off on those hot summer days. Located in Midtown center to museums, unique bar & restaurant concepts, Chase Field, The Footprint Center - the list goes on. We hope you enjoy all AZ has to offer!

Top guest favourite
A cozy living area features a white sectional sofa adorned with decorative pillows. A round coffee table sits atop a textured area rug, complemented by a plant and a decorative statue. Natural light streams through the two casement windows, illuminating the space.
Home in Coronado
4.95 out of 5 average rating, 303 reviews

Elegant Study of Light in Arty Coronado Historic

A zen-like designer creation with a focus on the natural light throughout this historic 1931 brick duplex. Original wood floors and casement windows, with elements of functional new in the kitchen and bathroom. Suspended bed. Private patio with soaking tub, fire pit and hammock. Short walk to the best local foodie destinations. 5 minutes to downtown, and yet in the heart of one of the most vibrant Phoenix neighborhoods. Owned, designed and operated by a local team with deep Airbnb experience.

Top guest favourite
A bedside table features a Smart Home device, providing convenient voice control. The stylish headboard frames a spacious bed adorned with crisp white bedding. Soft lighting enhances the clean and modern decor of the room, creating an inviting atmosphere.
Guest house in Willow
4.97 out of 5 average rating, 206 reviews

PHX's Modern Midtown Carriage House, Free Parking

Experience the perfect blend of historic charm and modern comfort in the heart of Phoenix's Midtown. Our beautifully designed Carriage House offers a unique guest quarters, complete with a full kitchen, luxurious queen bedding, and a private patio. Step outside and explore the vibrant neighborhood, filled with local restaurants, shops, and cultural attractions. Book your stay at the Midtown Carriage House today and discover the best of Phoenix living. check out on insta @midtowncarriagehouse

Guest favourite
The exterior of a charming studio guesthouse is visible, showcasing a brown brick facade and a well-kept entrance. A small pathway leads to the door, and palm trees can be seen in the background against a bright blue sky.
Guest house in Phoenix College
4.97 out of 5 average rating, 1,261 reviews

Private, Sparkling Clean Historic DTPHX Guesthouse

This charming studio guesthouse in the Campus Vista historic district is a fantastic find! Situated in a friendly neighborhood in the heart of Phoenix, this newly remodeled living space is cozy and practical, surpassing many of the similar properties in quality and character. A short ten-minute drive from the Sky Harbor Airport, and located within walking distance to two major bus lines and the light rail, the guests are sure to enjoy the easy access to all the popular downtown destinations.

Top guest favourite
A cozy bedroom featuring a spacious bed with a custom leather headboard. A large black and white mural of cacti adds character to the room. A modern pendant light hangs above, complementing the warm tones of the wooden bed frame and the textured beige bedding.
Guest suite in Encanto
4.99 out of 5 average rating, 350 reviews

Private, desert-chic casita in vibrant Midtown PHX

Welcome to Casita Amelia, a modern rustic retreat central to all the action Phoenix has to offer. Welcoming and cozy, this newly updated private guest suite has all the luxuries of a modern hotel suite while being quietly tucked away in a cute Midtown neighborhood. Walk to Melrose District. You're also just 5-10 mins by car to Uptown & Camelback Corridor, 10 mins to Downtown (Footprint Center, Chase Field, Arizona Financial), 15 mins to Sky Harbor Airport, and 20 mins to State Farm Stadium.

Guest favourite
The outdoor pool area features a clear blue pool with a gently sloped entry. A green float is positioned in the water. Surrounding the pool are various plants and a shaded patio area with a built-in grill, offering a relaxing space for outdoor activities.
Guest house in North Encanto
4.9 out of 5 average rating, 217 reviews

Private Casita w/ Pool* & BBQ in Historic Melrose

*PLEASE READ HOUSE RULES IN "OTHER THINGS TO NOTE" AREA BEFORE BOOKING* Under no circumstance can one book the Airbnb for another guest . This violates our house rules as well as Airbnb policy. Read more under HOUSE RULES for more details. Our cozy casita is located in the Woodlawn Park neighborhood, a short car ride from the Melrose and Willo Districts. Located near some of the best restaurants in Phoenix, this is the perfect stay for visitors who want to explore the local food scene.

Guest favourite
Home in Phoenix
4.95 out of 5 average rating, 478 reviews

Uptown Historic Home | Resort Style Outdoor Space

Experience Monarch House in a Phoenix Historic District—your spa-like retreat with unique artistic touches. The well-designed interior features a dining room and a fully equipped kitchen, perfect for memorable meals. Located in Uptown Phoenix, enjoy trendy restaurants, local boutiques, and vibrant nightlife just minutes away. Seamlessly switch between two private outdoor spaces and a shared courtyard, featuring an outdoor dining room and cozy fire pit.

Guest favourite
A cozy and inviting guest space is framed by wooden shelving, displaying various decorative items and plants. A spacious bed is positioned in the center, complemented by soft lighting from a ceiling fan. Windows allow natural light to brighten the area, enhancing its warmth.
Guest suite in Encanto
4.94 out of 5 average rating, 268 reviews

Charming Guesthouse w/ Full Kitchen & Pool

You'll love your private stay in our charming space, centrally located in Phoenix's historic Melrose District. It's perfect for folks staying several days: powerful air conditioning, private laundry room, and access to a kitchen and our outdoor pool. You'll be a 10 minute drive from downtown Phoenix and a 15 minute drive from Sky Harbor Airport. With a private entrance and a dedicated covered parking spot, your stay couldn't be more convenient!

Top guest favourite
A spacious bed adorned with neutral linens is positioned against a striking geometric accent wall. Soft yellow and blue cushions add comfort to the seating area in front, while warm light is provided by lamps on either side of the bed.
Guest suite in Encanto
4.96 out of 5 average rating, 202 reviews

Private Central Encanto Golf Course Casita

As frequent Airbnb guests, we are excited to provide the same comfortability and excellent customer service that we've become accustomed to. Guests can enjoy the privacy of their own private casita with a dedicated entrance and parking. The casita includes a kitchen equipped with a stove, refrigerator, and microwave. It also includes its own bathroom and an extremely comfy bed. We want our guests to feel at home here!

Popular amenities for Osborn Medical Center, Phoenix holiday rentals