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House holiday rentals in Mesa County

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Top-rated house rentals in Mesa County

Guests agree: these houses are highly rated for location, cleanliness and more.

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Guest favourite
A hot tub is situated on a patio area, surrounded by a white fence. Two hanging egg chairs provide cozy seating. Soft landscape lighting reflects off the water, with a twilight sky featuring distant clouds and a colorful sunset in the background.
Home in Grand Junction

420Friendly_HotTub_12kGameArcade_WineBar_5Bed

✨This is 420 Friendly home and you are welcome to smoke and use any marijuana products you would like in the comfort of the house. (no tobacco) I provide smoking accessories that are clean and sanitized after each guest and kept safe in a kitchen cabinet out of reach of kids. Dogs are welcome with a $50 fee. ⭐Multiple Wineries ➡15 min drive ⭐Mesa University ➡5 min drive ⭐Airport➡ 5 min drive ⭐Downtown GrandJunction ➡8 min drive ⭐Amtrak Train Station➡10 min drive ⭐Palisade Orchards ➡15 min d

4.89 out of 5 average rating, 218 reviews
Top guest favourite
A stylish living area features a decorative fireplace adorned with intricate tile. A modern gray armchair sits beside a round wooden table that holds books and a vase of yellow flowers, while large windows invite natural light and provide views of the outdoor landscape.
Home in Palisade

Modern Pali Farmhouse & Vineyard with hot tub

This spacious newer home with a hot tub is the perfect base for all your Palisade & Grand Valley adventures! Situated on 5 acres along the Fruit & Wine Byway, relax & take in the vineyard or mountain views from nearly every window! Go wine tasting, take a hike, go road or mountain biking, visit an orchard or lavender farm, paddle board on the Colorado river, ski at nearby Powderhorn, & more! Then after your day of adventuring enjoy the fireplace, outdoor living space, or a soak in the hot tub.

4.99 out of 5 average rating, 105 reviews
Top guest favourite
An aerial view captures the unique architecture of the home against the backdrop of the Colorado National Monument. Surrounding natural vegetation blends with the rugged terrain, while a winding driveway leads to the house, showcasing its integration within the landscape.
Home in Grand Junction

5200SqFt, Hillside Rock In House, Stunning Views

One of a kind 4BR 3BA 5,200 sqft home. Stunning views of the CO Ntl Mnt and entire Grand Valley. Our grandpa, a home builder, designed this rustic house as a masterpiece for his family. He wanted it to be part of nature, so he fit it between trees and inside left exposed the massive sandstone slab on which it’s built. This large house has entertained our family and friends for generations, and we’re thrilled that now you can share it with yours, too. Be in nature but minutes from downtown!

4.92 out of 5 average rating, 217 reviews
Top guest favourite
The farmhouse, featuring a classic white exterior and a sloped metal roof, is surrounded by lush greenery and colorful flower beds. A path leads from the gravel driveway to the welcoming entrance. In the backdrop, rugged cliffs rise, adding to the scenic rural setting.
Home in Palisade

A Peach of a Farmhouse

Located on the Scenic Fruit and Wine Byway, our newly remodeled air-conditioned farmhouse is on a three-acre peach farm within easy biking distance to Palisade. Enjoy downtown Palisade's farmers market, distillery, and brewery. We're moments from many wineries and trailheads including Mt. Garfield & Palisade Rim. Begin, end or spend your day lounging on the front porch in the shade of mature peach trees or enjoying views of the rugged Palisades seeming to rise just outside the back door.

4.98 out of 5 average rating, 221 reviews
Top guest favourite
A spacious porch features wooden flooring and is lined with tranquil seating options, including a set of chairs and a swing. Natural light filters through the surrounding trees, enhancing the peaceful outdoor space.
Home in Delta County

2 Bedroom Ranch House

Just a mile off of Highway 65 sits Tongue Creek Ranch. The Ranch is located in the fertile valley junction of Tongue Creek & Surface Creek. Enjoy your own private 2 bed 1 bath ranch house. Both bedrooms have a super comfy pillow top queen size bed. WIFI is a fast 1gig fiber optic line. Enjoy a full kitchen, washer and dryer, and a sofa in the family room. The front patio is always in the shade. Ask about the optional cabin on site for use as a private detached room for overflow family.

4.96 out of 5 average rating, 299 reviews
Top guest favourite
A contemporary home is presented with a wooden exterior, surrounded by a gravel area. Large glass doors offer views into the interior space. Two outdoor chairs are positioned on the patio, with wildflowers and vegetation framing the scene.
Home in Loma

Fruita/Loma Guest House at the Perfect Day Getaway

This newly constructed "Green" home is a mix of modern and country styles and will surely inspire you to enjoy all of the outdoor activities the Grand Valley has to offer. The Perfect Day Getaway house is located on a quaint farm within 8 minutes of world-class hiking, mountain and road bicycling, and river rafting. It is a great launching point for day trips to Moab and the Grand Mesa as well! It was built to maximize the southern exposure and views of the Colorado National Monument.

4.99 out of 5 average rating, 718 reviews
Top guest favourite
A wooden pergola with a dining table and chairs is situated in a garden area, framed by lush greenery. A yellow building and a red barn with a green roof are visible in the background, set against a colorful sunrise sky.
Home in Palisade

Galloway Ranch Palisade Colorado

Recent review: The best place we've ever stayed at, hands down! The location felt like a dead end road, yet close to everything. The yard had beautiful flower beds, not to mention the amazing view of Mt. Garfield! The house itself was very comfortable and had anything you can imagine in the kitchen, making a few at home dinners a breeze. Owners Note: One (1) dog 45 lbs max allowed unless an additional dog is approved in advance, please include # of people and # of dogs when booking.

4.97 out of 5 average rating, 298 reviews
Top guest favourite
Home in Grand Junction

Modern Farmhouse -Historic Downtown Grand Junction

Welcome to Your Downtown Retreat — a newly remodeled historic home in the heart of Grand Junction. Perfect for family getaways, work trips, or a peaceful escape, this charming home blends modern comforts with timeless character. 📍 Walk to Downtown GJ’s best dining + shopping 🍳 Brand-new kitchen, perfect for family meals 🌿 Covered patio + beautifully landscaped backyard ☀️ Cozy sunroom for coffee, tea, reading, or relaxing ✨ Spacious master suite w/ king bed + en-suite bathroom

4.94 out of 5 average rating, 152 reviews
Top guest favourite
A charming farmhouse is set against a backdrop of rocky hills. A gravel path leads to the house, surrounded by a green lawn and mature trees. A covered porch offers seating, while a spacious garage stands nearby, creating an inviting outdoor space.
Home in Palisade

Quaint Farmhouse on Palisade Peach Orchard

Quaint 3 bedroom 1 bath farmhouse located on a 5 1/2 acre working peach orchard in the heart of fruit & wine country. Nice walk or bike ride to wineries, orchards, & shuttle stop for festivals. Step back in time and enjoy a slower pace here at the farm. Great view from the front porch. The home is vintage in layout and simplicity. It has the original farmhouse kitchen. Train lovers will enjoy watching the train go by! Please see additional info in details & pictures.

4.96 out of 5 average rating, 124 reviews
Guest favourite
A modern house is set against a clear night sky filled with stars. The exterior features large glass doors, providing a seamless view of the surroundings. A spacious patio area is visible, bordered by natural landscaping, creating a sense of tranquility and connection to nature.
Home in Palisade

Rapid Creek Retreat

High above the town of Palisade, nestled in the foothills of the Grand Mesa, is the Rapid Creek Retreat. Surrounded by untouched public land you will experience the true gift and grit of Colorado. Enjoy views of the big sky from sunrise to sunset and beyond for magical star gazing. We planned for this home to be ours, every detail of this home was built with intent and love. The feeling here is truly special. For those ‘rough around the edges. Sincerely, The Busch’s

4.97 out of 5 average rating, 178 reviews
Guest favourite
A modern two-story home is showcased, featuring a striking wood exterior and large front windows. A two-car garage is visible, alongside a spacious driveway. The well-manicured lawn is flanked by trees and a fully fenced area, enhancing the property's curb appeal.
Home in Grand Junction

4 beds-hot tub-yard&AirConditioning! NO XTRA FEES!

This home is a great choice for larger groups or just a few! Centrally located in Grand Junction with plenty of parking and a fully fenced yard. Two living areas and a large, fully stocked kitchen give you lots of room to stretch out. The bedrooms are designed with flexibility in mind! I've got two other properties in town right next to each other that each sleep 5 - let me know if you are interested. Now cooled by central air conditioning and mini-split system.

4.97 out of 5 average rating, 118 reviews
Top guest favourite
A two-story house is seen from the outdoor area, featuring a patio with several chairs and tables. A gravel driveway leads to lush vineyards in the background, framed by distant mountains under a clear blue sky.
Home in Palisade

Love Orchard

You will enjoy breathtaking endless views of orchards, vineyards and the Bookcliff mountains and amazing sunsets from the bright, open great room and balcony. You may think you are in the clouds! The peace and quiet you will feel in this lovely new home will surely refresh you. Located on the fruit and wine byway, there are 6 wineries within 3 miles yet you are only 2.5 miles from downtown Palisade and its plentiful offerings. This home is calling your name!

4.99 out of 5 average rating, 153 reviews

Popular amenities for house rentals in Mesa County

KitchenWifiPoolFree parking on premisesAir conditioning

House rentals with a pool

Top guest favourite
A private hot tub is illuminated with soft blue light, positioned under a shelter. A cozy seating area features comfortable chairs adjacent to a fire pit, with warm flames flickering. Twinkling string lights provide a welcoming ambiance against the night sky.
Home in Palisade

Peach Pad! hot or cool tub 2 bedrooms 2 bathrooms

4.93 out of 5 average rating, 309 reviews
Guest favourite
A spacious backyard features a multi-level patio with ample seating options. A pool is centrally located, surrounded by lounge chairs and landscaped gardens. The home's stone facade stands in the background, complemented by trees creating a natural setting.
Home in Grand Junction

The Grant House

4.87 out of 5 average rating, 45 reviews
Guest favourite
Home in Grand Junction

Relaxing family getaway

4.88 out of 5 average rating, 33 reviews
Top guest favourite
A heated pool is surrounded by a spacious patio, with several lounge chairs arranged nearby. Lush green grass artificial turf contrasts with the stone landscaping. The scenic backdrop includes rocky outcrops and greenery, enhancing the outdoor relaxation area.
Home in Grand Junction

Pool, hot tub, views and close to everything

5.0 out of 5 average rating, 88 reviews
Top guest favourite
The exterior of a modern single-story home is showcased against a colorful evening sky. The spacious pool is framed by a stone patio and lined with lounge chairs. Large glass windows illuminate the interior, emphasizing an inviting outdoor retreat, surrounded by gentle landscaping.
Home in Palisade

Private Pool + Stunning Views | 3BR/3.5BA

5.0 out of 5 average rating, 66 reviews
Guest favourite
A vibrant outdoor area features a sparkling private pool, surrounded by lounge chairs and colorful umbrellas. String lights create a warm ambiance above a tiki bar, while a large inflatable swan floats in the water. Lush greenery complements the tranquil setting.
Home in Grand Junction

Pool Hot Tub Mini Golf Game Room Sleeps 12

4.93 out of 5 average rating, 67 reviews
Guest favourite
Home in Clifton

Corner View @ Palisade Legends

5.0 out of 5 average rating, 8 reviews
Guest favourite
The exterior of a 1950s log cabin farmhouse features a wooden porch with a railing, leading to the entrance. A gravel pathway surrounds the building, with trees providing shade and a clear blue sky above. The structure displays natural wood and stone elements.
Home in Grand Junction

Farmhouse Basement Apartment

4.95 out of 5 average rating, 40 reviews

Weekly house rentals

Top guest favourite
The exterior of a blue house is presented, featuring a well-maintained lawn and a gravel pathway. A covered front porch is visible, along with two yellow chairs and a small table. A two-car garage is located on the right side of the image.
Home in Fruita

Maple Downtown Fruita

4.96 out of 5 average rating, 359 reviews
Guest favourite
Home in Palisade

The Pali House - 10 Acres & Wine Country Views

4.92 out of 5 average rating, 258 reviews
Guest favourite
A historic house features a charming front porch with a decorative door and a welcoming flower pot. Light-blue and white siding is complemented by purple accents. A well-maintained lawn and a stamped concrete area provide space for outdoor seating and relaxation.
Home in Grand Junction

Walkable Downtown Historic Home: A/C, Patios, BBQ

4.92 out of 5 average rating, 288 reviews
Guest favourite
A charming house appears set back from the sidewalk, framed by lush green trees. A spacious covered porch is adorned with comfortable seating. Flower pots add color to the landscape, and neighboring homes contribute to the inviting atmosphere of the quiet neighborhood.
Home in Grand Junction

GJ Relax on Rood - Hot tub - Location!

4.94 out of 5 average rating, 455 reviews
Top guest favourite
A single-story house with a red roof and white exterior is set against a clear blue sky. A spacious front yard with trimmed hedges and trees surrounds the home. A two-car garage is visible on the right side, enhancing the welcoming appearance of the property.
Home in Palisade

The Tree House - Relax, unwind, enjoy...

4.97 out of 5 average rating, 104 reviews
Guest favourite
An open living space showcases a gray sofa with a yellow throw blanket draped over it. A small black table sits next to the couch, flanked by two accent chairs. A dining table is visible in the background, accompanied by light wood flooring and natural light filtering through the windows.
Home in Grand Junction

Gunnison Bungalow

4.9 out of 5 average rating, 157 reviews
Top guest favourite
An exterior view of a modern single-story building is seen, featuring large windows that reflect natural light. A grill is positioned in front, complemented by two outdoor chairs nearby. Surrounding gravel adds texture to the landscape, with green grass visible in the foreground.
Home in Loma

Highline House located near bike trails & the lake

4.96 out of 5 average rating, 379 reviews
Top guest favourite
A cozy fire pit area is surrounded by colorful adirondack chairs, inviting relaxation. The two-story house in the background features black accents against a light-colored exterior, framed by trees and a grassy yard, with a white fence visible in the distance.
Home in Fruita

The Centennial House ~ Historic 6BR, 3BA home.

4.97 out of 5 average rating, 261 reviews

Private house rentals

Top guest favourite
A panoramic view captures dramatic mountain ranges under a dynamic sky, with soft light highlighting the peaks. Shadows and sunlight create a range of tones across the landscape. In the foreground, greenery and structures provide a base to the vast scenery beyond.
Home in Grand Junction

Little Park Road Retreat - Hot Tub with a View

4.97 out of 5 average rating, 179 reviews
Top guest favourite
A spacious living room features a large brown sectional sofa with decorative pillows, positioned to face a white entertainment center and a wall-mounted television. Large windows provide natural light, while the hardwood floor complements the modern design of the space.
Home in Fruita

The Wandering Nomad

4.97 out of 5 average rating, 367 reviews
Superhost
An open concept kitchen features modern stainless steel appliances, including a microwave and dishwasher. Ample counter space is complemented by a double sink, while a ceiling fan hovers above. Natural light enters through sliding glass doors that lead to an outdoor area.
Home in Grand Junction

Mesa Gardens GJ

4.83 out of 5 average rating, 352 reviews
Top guest favourite
Home in Grand Junction

Family friendly, quiet & comfy 3BR home North area

4.96 out of 5 average rating, 209 reviews
Guest favourite
A charming exterior of a house features a welcoming front porch, framed by large windows with blue curtains. The facade combines wood shingles and blue siding, complemented by decorative elements such as flags and potted plants. A landscaped front yard with stone pathways enhances the inviting appearance.
Home in Grand Junction

1910 Reinvented

4.95 out of 5 average rating, 112 reviews
Guest favourite
A modern living room features a sectional sofa with green accent pillows and a coffee table in the center. Large windows bring in natural light, while a cozy rug lays beneath. A side table and a plant add warmth to the space, complemented by framed artwork on the walls.
Home in Grand Junction

Downtown Launchpad for your Colorado Adventures!

4.96 out of 5 average rating, 308 reviews
Guest favourite
Home in Grand Junction

Near downtown/Hiking/Biking, Lakes / river

4.83 out of 5 average rating, 151 reviews
Top guest favourite
A spacious log cabin features a charming facade with wooden shutters adorned by flower boxes. The surrounding landscape showcases rolling hills and a bright blue sky with scattered clouds, enhancing the rustic and inviting appearance of the home.
Home in Palisade

Peach Chalet, views, quiet, 5 min to downtown

4.98 out of 5 average rating, 127 reviews

Destinations to explore