Guest house holiday rentals in Mesa County

Peaceful Cabin Near National Monument and Downtown

Peaceful and airy, our centrally located cabin feels remote, but is just minutes from downtown Grand Junction amenities. Biker/Hiker Dream Location: 5 min drive to Lunch Loops mountain biking and hiking trails, 2 min bike ride from the driveway onto Little Park Rd, 13 minute drive to Bang's Canyon Trailhead. 5 min drive to yoga studio, groceries, and coffee. Cleanliness is our #1 priority! Bright and intentionally furnished with decor by local artists, our heart has gone into every detail.

Yonder Mountain Retreat

A beautiful guesthouse on 5 acres a few miles north of the quaint town of Cedaredge. Multiple access points to the Grand Mesa, the ultimate outdoor playground for snowmobiling, hiking, motorcycling, ATVs, UTVs, fishing & hunting! Extra parking for motorcycles, ATVs, UTVs, or snowmobiles! YMR permits guests to bring one furbaby without pre-approval ($100 pet fee still applies). To bring more than one pet, pre-approval & addt’l. fees apply. One external security camera by the kitchen door.

Liberty Lodge-a peaceful hub for outdoor fun

New guest house in a peaceful location has all the amenities you need. Loads of BIKING, HIKING, OHV, HORSEBACK trails are a short drive Small town atmosphere, shopping, dining and festivals in Fruita, 10 minute drive Very close to Highline Lake State Park 10 min to the Colorado Riverfront trail 1.5 hrs to MOAB/ARCHES Natl Park 1 hr to Grand Mesa and POWDERHORN Ski Resort 20 min to Independence Monument 20 min to Rabbit Valley Trailer parking (give us a heads up if you have a trailer) No Pets

Charming, private guest suite in downtown Fruita!

A cozy and private suite (ADU) close to downtown Fruita and i-70 exit. The suite has a private entrance with keypad for self check-in. The 1br 1ba suite has mini fridge, microwave, and coffee maker. Basically a hotel room. There is no kitchen or TV. Off-street parking is available. Shared fenced in yard for pets (shared w. host and host's friendly dog). Air-conditioned in summer. Late fees assessed for unauthorized late checkout (pls see rules). Fresher Hospitality, LLC STR-2023-165

The Pali House - Beautiful views on 10 acres!

Beautiful property with a private, walkout entrance and access to a large backyard. Just 5 minutes from Palisade’s wineries and dining, and 40 minutes to Powderhorn Ski Resort. Ideal for couples seeking a romantic getaway or ski retreat. Modern amenities, tons of space, fully stocked kitchen, fast Wi-Fi, and stunning sunsets make this a perfect year-round destination. This spot is perfect for couples and pet owners looking to relax, explore, and enjoy wine country. Your hosts, Joe & Trish

Colorado river guest house

Welcome to Happy Tails animal sanctuary we are a nonprofit animal rescue in palisade wine country. 10 acre animal sanctuary w alpaca, goats, pigs, dogs, chickens peacocks even a emu that all free range. Fish, kayak, paddleboard, canoe on our 2 acre fully stocked fishing lake. Float the Colorado river from Riverbend park in Palisade to our private beach. The views of the Colorado river, Grand Mesa & mount Garfield are breathtaking the animals are all friendly and love people

Fruita Retreat + View ⛰🌵

Peacefully situated beyond city limits yet just minutes away from downtown Fruita, our cozy haven offers ample open space for relaxation on your private patio, where you can soak in mountain views & beautiful sunsets while gathered around the cozy gas firepit. Outdoor enthusiasts will appreciate our property's easy access to trails, providing ample opportunities for hiking, biking, and exploration. Discover the tranquility and convenience of our countryside escape!

Desert's Edge Fruita. Pet/Bike Friendly-4 acres

Pet Friendly! Ideal for a couple or single person but can accommodate up to 4 people utilizing the foldout sofa bed in the living room. Desert's Edge provides an authentic Fruita experience to all seeking an outdoor Colorado adventure. Fruita is known for its world-famous mountain biking trails, and Desert’s Edge is centrally located to all the action, but we hope to highlight more Fruita attractions for you to explore during your stay.

Chic 2 Bedroom Cottage with Monument Views

Mountain biking, hiking, motorcycling? It's all right here! Our newly built 2 bedroom private cottage sits at the base of Colorado National Monument and is thoughtfully designed to help you relax and unwind. Ride out the back door or take a short drive to the legendary trails of Grand Junction and Fruita. When the fun is done, rest your legs on your secluded patio and watch the sunset over the sand stone towers looming in the backyard.

Flat in Downtown Fruita w/ Private Garage Parking

Our private guesthouse is steps away from historic downtown Fruita. A cozy, clean, two-story loft attached to a private garage for secure parking. The unique guesthouse and garage are detached from the main house. Climb the ladder to the bedroom loft with skylights and enjoy our new air conditioning cooling system. Great shower and fresh linens. Private entrance. Peaceful garden. Easy access to I-70. pc#0045-23B

The Gunnison Guesthouse

Free off-street parking | Cleaning fees included in nightly rate | Complimentary coffee + tea, snacks + organic apples Built in 2017, this 700-square foot guesthouse offers a beautiful home away from home, centrally located in the heart of Grand Junction. Just blocks from CMU, Stocker Stadium, Suplizo Field, and less than a mile from downtown. Grand Junction named to the New York Times "52 Place to Go in 2023"

Guest House with 360 Mountain Views

Enjoy the peace and quiet of nature just 8 minutes from downtown Paonia at the Zephyr Ranch guest house! You'll have easy access to hiking, mountain biking, and incredible views of Mt. Lamborn and Landsend. Black Canyon National Park is also just a short drive away! Perfect for adventure travel, staycations, and anyone who wants to experience all that Western Colorado has to offer.