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House holiday rentals in Mytilini

Find and book unique houses on Airbnb

Quick stats about house rentals in Mytilini

  • Total holiday rentals

    Explore 100 holiday rentals in Mytilini

  • Nightly prices starting at

    Mytilini holiday rentals start at €17 per night before taxes and fees

  • Verified guest reviews

    Over 2,200 verified reviews to help you choose

  • Family-friendly holiday rentals

    40 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 30 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    100 of Mytilini holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mytilini rentals

  • 4.8 Average rating

    Mytilini stays are highly rated by guests – averaging 4.8 out of 5!

Top-rated house rentals in Mytilini

Guests agree: these houses are highly rated for location, cleanliness and more.

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Guest favourite
A newly built villa is shown beside a sandy beach, featuring blue shutters and a shaded outdoor seating area. A tree provides natural shade, with the crystal blue waters visible in the background, and distant mountains lining the horizon under a clear sky.
Home in Plomari
4.89 out of 5 average rating, 102 reviews

Floras Charming Waterfront Villa

Flora's charming waterfront villa is located in the centre of the traditional picturesque village of Melinda, situated 6 km west of the village of Plomari. Our villa is situated literally on the beach, which is known for its crystal blue waters. The newly built modern house is fully equipped with all conveniences, such as a modern kitchen, air condition units in all rooms, tv, wi-fi etc. The famous traditional greek taverna of Maria is right next door, where you can enjoy local delicacies all day. In Our quiet villa you will experience greek at its summer, watching the sunset.

Guest favourite
An elevated view of the living area displays a spacious layout with high ceilings and wooden beams. Large windows allow natural light to fill the room, where a contemporary sofa and stylish coffee table create a cozy seating area. Decorative elements add character to the wall.
Home in Plomari
4.91 out of 5 average rating, 23 reviews

Beautiful Plomari Cottage

Newly renovated, spacious and stylish house in a quiet street at the heart of Plomari is a perfect place for couples, groups and families of up to 6 people. It boasts an ultra-high ceiling with a lovely gallery. Fully equipped kitchen, dining area, bedroom and full bathroom on ground floor; additional bedroom, full bathroom, open space with a sofa-bed in the gallery. Amoudeli beach is a 250m stroll. Important note: for safety reasons, children under 12 years old are not allowed up at the gallery

Top guest favourite
A dining table set on an outdoor terrace is arranged for a meal. Plates are placed beside crystal glasses, with a colorful spread of grapes, watermelon, and other fruits displayed on a platter. A glass pitcher and bottles, including a wine bottle, complete the inviting setting.
Home in Mytilini
4.98 out of 5 average rating, 94 reviews

Aegean View Resort # The House

Tranquillity, relax and comfort best describe this house set in absolute nature in a peaceful suburb, only a few minutes away from the heart of the Mitilini. The property featuring stunning architectural details that provides guests with a high level of comfort and style but it can also be your base for exploring the rest of the beautiful and big island.It is perfect for families, couples or a group of friends looking for spacious areas, large terraces, comfort and privacy.

Guest favourite
A serene cottage sits by the water's edge, framed by lush greenery and a distant hill. The home showcases a traditional design with a tiled roof and multiple windows, inviting bright natural light. The tranquil surroundings highlight the peaceful waterfront setting.
Home in Lesbos
5.0 out of 5 average rating, 28 reviews

Ambelos, Lesvos Beach House

Welcome to Ampelos Cottage, an 85 sqm beachfront retreat where the sea is right at your doorstep. Blending modern comfort with authentic Greek charm, it’s the perfect escape for families and couples seeking relaxation and unforgettable moments. Wake up to the sound of the waves, enjoy coffee by the sea and watch the sunset with a glass of wine. Explore Molyvos, discover the tavernas of Anaxos, or simply unwind surrounded by breathtaking sea and mountain views.

Top guest favourite
A spacious sleeping area is highlighted by a relaxing atmosphere. A large, vintage bathtub is positioned nearby, and a small table with fresh flowers adds a touch of color. Natural light filters in, enhancing the room's inviting design.
Home in Mytilini
4.99 out of 5 average rating, 67 reviews

Ioanna's traditional house in the center of 140m2

Traditional building, built in 1880, in the historic city center. Renovated in 2008. It is aimed at lovers of authenticity, antiques and art! Ideal for a romantic vacation (the choice of honeymooners). It offers a comfortable stay for families with young children and babies! A 5-minute walk from the port and the beach, cafes, restaurants, bars, as well as most of the attractions of Mytilene! Children under 12 stay free of charge!

Guest favourite
A spacious dining area features a long wooden table surrounded by modern black chairs. Large windows on either side allow natural light to fill the room, revealing views of the surrounding landscape. A stone fireplace adds a touch of warmth.
Home in Plomari
4.97 out of 5 average rating, 36 reviews

Iris Home

Our two-level recently renovated maisonette Iris Home is located in the city center. It has a fully equipped kitchen and dining area to enjoy your food with your family and friends overlooking the sea. The two bedrooms and the bathroom are on the lower level and continue the view of the endless blue of the Aegean Sea. Within a 2-minute walk, you can find the city's marina, restaurants, cafes and other shops.

Guest favourite
The exterior showcases a two-story traditional building with maroon shutters framing the windows, which are adorned with white lace curtains. A small outdoor seating area features a patterned tablecloth, complemented by light-colored chairs, inviting relaxation in a serene setting.
Home in Taxiarches
4.82 out of 5 average rating, 115 reviews

PanDesSia

"PanDesSia" is a traditional house in Mytilene, with Lesbian architecture. It is located in "Kayani", close by the famous "Antonis" Ouzeri. Offers a veranda with a fantastic view of the Aegean Sea, the town and the harbor of Mytilene and the Turkish coasts. It is only 6km from the town of Mytilene and 4km from the airport. It has two bedrooms overlooking the sea and can accommodate at least 4 people.

Top guest favourite
Home in Mytilini
5.0 out of 5 average rating, 21 reviews

Mytilene Luxury Villa | Garden level

Enjoy the private garden level apartment of our luxury villa with 3 bedrooms and panoramic views over Mytilene and the Aegean Sea. You’ll have a private entrance, exclusive use of the garden and outdoor areas, ensuring complete privacy. Just 5–7 minutes by car from Mytilene center, the port, and restaurants. Perfect for families and friends looking for comfort, style, and peace.

Top guest favourite
A cozy seating area is positioned near large windows overlooking the sea. The stone wall adds a rustic touch, while two tall chairs with green cushions invite relaxation. Natural light floods the space, highlighting the nearby decorative items and the calm waters outside.
Home in Nyfida
4.94 out of 5 average rating, 31 reviews

Pelagia's House

Pelagia's house is a seaside house that has been recently renovated while keeping its traditional character along with the memories of many carefree summers. The house has 2 bedrooms with one double and two single beds, a fully equipped kitchen, a very comfortable bathroom, air conditioning and wifi in all areas This seaside house is ideal for a quiet and relaxing vacation.

Guest favourite
A charming villa with a light-colored façade features green shutters and a balcony. Lounge chairs are arranged near a private pool, reflecting the clear blue sky. Olive trees surround the property, creating a peaceful outdoor setting, while the pool area is easily accessible.
Home in Agia Varvara
5.0 out of 5 average rating, 18 reviews

Ouzo Traditional House with privatepool & parking

This villa, was the vaccation house of a local oil trader that has been completely refurbished in 2018. While maintaining its initial external design, has been internally redesigned to offer all possible confort and amenities to the guests. The villa, surounded by pine & olive trees, is located about 200 meters away from the east end of the famous Agios Isidoros beach.

Guest favourite
Home in Plomari
4.89 out of 5 average rating, 18 reviews

the Workshop

And old workshop is restored and transformed to a one bedroom house with a gallery ready to host families or friends till four people.The yard completes the scenary for the perfect holiday in lovely Plomari. Ground floor: living room, kitchen, bedroom with a double bed and a bathroom with a shower. Gallery : a double bed (not a separate bedroom)

Guest favourite
Home in Mytilini
5.0 out of 5 average rating, 16 reviews

D. Bernardaki Garden House

Welcome to Bernardaki Garden House! Nestled in a traditional neighbourhood, our professionally designed apartment offers the perfect blend of modern comfort and timeless charm in the heart of Mytilene. Why does our proposal stand out among the options in the whole Mytilene? There's a reason, and we're eager to share it with you!

Popular amenities for house rentals in Mytilini

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