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House holiday rentals in Mytilini

Find and book unique houses on Airbnb

Quick stats about house rentals in Mytilini

  • Total holiday rentals

    Explore 100 holiday rentals in Mytilini

  • Nightly prices starting at

    Mytilini holiday rentals start at €17 per night before taxes and fees

  • Verified guest reviews

    Over 2,200 verified reviews to help you choose

  • Family-friendly holiday rentals

    40 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 30 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    100 of Mytilini holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mytilini rentals

  • 4.8 Average rating

    Mytilini stays are highly rated by guests – averaging 4.8 out of 5!

Top-rated house rentals in Mytilini

Guests agree: these houses are highly rated for location, cleanliness and more.

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Guest favourite
A newly built villa is shown beside a sandy beach, featuring blue shutters and a shaded outdoor seating area. A tree provides natural shade, with the crystal blue waters visible in the background, and distant mountains lining the horizon under a clear sky.
Home in Plomari

Floras Charming Waterfront Villa

Flora's charming waterfront villa is located in the centre of the traditional picturesque village of Melinda, situated 6 km west of the village of Plomari. Our villa is situated literally on the beach, which is known for its crystal blue waters. The newly built modern house is fully equipped with all conveniences, such as a modern kitchen, air condition units in all rooms, tv, wi-fi etc. The famous traditional greek taverna of Maria is right next door, where you can enjoy local delicacies all day. In Our quiet villa you will experience greek at its summer, watching the sunset.

4.89 out of 5 average rating, 103 reviews
Superhost
Home in Mytilini

Kiki's house in the castle

Kiki's House is a comfortable space in the heart of the historic center of Mytilene, with a unique view of the Castle. The house can accommodate up to 5 guests, has 3 bedrooms, a spacious bright living room, a fully equipped kitchen, and a comfortable parking space. In the beautiful courtyard, you will enjoy moments of relaxation overlooking the historic walls of the castle. The property is ideal for families with children, couples, or groups looking for tranquility, comfort, and easy access to attractions.

5.0 out of 5 average rating, 4 reviews
Guest favourite
An elevated view of the living area displays a spacious layout with high ceilings and wooden beams. Large windows allow natural light to fill the room, where a contemporary sofa and stylish coffee table create a cozy seating area. Decorative elements add character to the wall.
Home in Plomari

Beautiful Plomari Cottage

Newly renovated, spacious and stylish house in a quiet street at the heart of Plomari is a perfect place for couples, groups and families of up to 6 people. It boasts an ultra-high ceiling with a lovely gallery. Fully equipped kitchen, dining area, bedroom and full bathroom on ground floor; additional bedroom, full bathroom, open space with a sofa-bed in the gallery. Amoudeli beach is a 250m stroll. Important note: for safety reasons, children under 12 years old are not allowed up at the gallery

4.92 out of 5 average rating, 26 reviews
Guest favourite
Olive trees frame a serene seafront view, where the water reflects the warm hues of a sunset. A grassy area extends, with a stone pathway leading toward the shoreline, creating a sense of tranquility amidst nature.
Home in Pyrgi

Traditional Stone House in Seafront Olive Grove

A beautiful olive grove 55sqm stonebuild estate on the Greek island of Lesvos (Lesbos), in the embrace of the amazing Gera Gulf at the south-eastern part of the island. A shelter of harmony, calm and peacefulness, at the beachfront of the crystal clear blue waters of the gulf, where you can swim and relax under the olive and pine trees with a unique sense of privacy, only 10 minutes away from the central city, port and airport of Mytilene. Hosts 2 adults and up to 2 children

5.0 out of 5 average rating, 12 reviews
Top guest favourite
A dining table set on an outdoor terrace is arranged for a meal. Plates are placed beside crystal glasses, with a colorful spread of grapes, watermelon, and other fruits displayed on a platter. A glass pitcher and bottles, including a wine bottle, complete the inviting setting.
Home in Mytilini

Aegean View Resort # The House

Tranquillity, relax and comfort best describe this house set in absolute nature in a peaceful suburb, only a few minutes away from the heart of the Mitilini. The property featuring stunning architectural details that provides guests with a high level of comfort and style but it can also be your base for exploring the rest of the beautiful and big island.It is perfect for families, couples or a group of friends looking for spacious areas, large terraces, comfort and privacy.

4.98 out of 5 average rating, 98 reviews
Top guest favourite
The tranquil night view captures three modern villas framed by lush greenery. A private pool is illuminated in soft blue, reflecting the clear sky. Warm light glows from the villas, highlighting their welcoming architecture against the serene backdrop.
Home in Mytilini

Pierres Blanches Residences 2

Discover the ultimate accommodation experience 1.5 km from the city center of Mytilene. With elegant design and modern amenities, our three autonomous detached houses, 120 sq.m. each, invite you to enjoy the tranquility and beauty of the island. Each villa has three comfortable bedrooms, two bathrooms, a spacious living room, an attic, a fully equipped kitchen and a private pool to cool off and enjoy the sun in the comfort of your own pool.

5.0 out of 5 average rating, 20 reviews
Top guest favourite
A spacious sleeping area is highlighted by a relaxing atmosphere. A large, vintage bathtub is positioned nearby, and a small table with fresh flowers adds a touch of color. Natural light filters in, enhancing the room's inviting design.
Home in Mytilini

Ioanna's traditional house in the center of 140m2

Traditional building, built in 1880, in the historic city center. Renovated in 2008. It is aimed at lovers of authenticity, antiques and art! Ideal for a romantic vacation (the choice of honeymooners). It offers a comfortable stay for families with young children and babies! A 5-minute walk from the port and the beach, cafes, restaurants, bars, as well as most of the attractions of Mytilene! Children under 12 stay free of charge!

4.99 out of 5 average rating, 74 reviews
Guest favourite
A logo for '4 Seasons Guest Room Mytilene' is displayed, featuring a stylized house silhouette against four colorful panels representing the seasons: green leaf, yellow sun, red maple leaf, and blue snowflake. The name is prominently presented in a bold font below.
Home in Mytilini

4 seasons

Fully furnished 38 sq.m. apartment, ideal for up to 2 guests — an ideal choice for couples or travelers seeking comfort and tranquility. The apartment is located in the traditional neighborhood of Synoikismos, very close to all local businesses (pharmacy, mini market, bakery, greengrocer, pastry shop, etc.) and just a few minutes away from the city center. It is an ideal choice for either a short getaway or a longer stay.

4.98 out of 5 average rating, 61 reviews
Guest favourite
A spacious dining area features a long wooden table surrounded by modern black chairs. Large windows on either side allow natural light to fill the room, revealing views of the surrounding landscape. A stone fireplace adds a touch of warmth.
Home in Plomari

Iris Home

Our two-level recently renovated maisonette Iris Home is located in the city center. It has a fully equipped kitchen and dining area to enjoy your food with your family and friends overlooking the sea. The two bedrooms and the bathroom are on the lower level and continue the view of the endless blue of the Aegean Sea. Within a 2-minute walk, you can find the city's marina, restaurants, cafes and other shops.

4.98 out of 5 average rating, 41 reviews
Guest favourite
The exterior showcases a two-story traditional building with maroon shutters framing the windows, which are adorned with white lace curtains. A small outdoor seating area features a patterned tablecloth, complemented by light-colored chairs, inviting relaxation in a serene setting.
Home in Taxiarches

PanDesSia

"PanDesSia" is a traditional house in Mytilene, with Lesbian architecture. It is located in "Kayani", close by the famous "Antonis" Ouzeri. Offers a veranda with a fantastic view of the Aegean Sea, the town and the harbor of Mytilene and the Turkish coasts. It is only 6km from the town of Mytilene and 4km from the airport. It has two bedrooms overlooking the sea and can accommodate at least 4 people.

4.82 out of 5 average rating, 116 reviews
Top guest favourite
Home in Mytilini

Mytilene Luxury Villa | Garden level

Enjoy the private garden level apartment of our luxury villa with 3 bedrooms and panoramic views over Mytilene and the Aegean Sea. You’ll have a private entrance, exclusive use of the garden and outdoor areas, ensuring complete privacy. Just 5–7 minutes by car from Mytilene center, the port, and restaurants. Perfect for families and friends looking for comfort, style, and peace.

5.0 out of 5 average rating, 22 reviews
Top guest favourite
A cozy seating area is positioned near large windows overlooking the sea. The stone wall adds a rustic touch, while two tall chairs with green cushions invite relaxation. Natural light floods the space, highlighting the nearby decorative items and the calm waters outside.
Home in Nyfida

Pelagia's House

Pelagia's house is a seaside house that has been recently renovated while keeping its traditional character along with the memories of many carefree summers. The house has 2 bedrooms with one double and two single beds, a fully equipped kitchen, a very comfortable bathroom, air conditioning and wifi in all areas This seaside house is ideal for a quiet and relaxing vacation.

4.94 out of 5 average rating, 35 reviews

Popular amenities for house rentals in Mytilini

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