
House holiday rentals in Mytilini
Find and book unique houses on Airbnb
Quick stats about house rentals in Mytilini

Total holiday rentals
Explore 100 holiday rentals in Mytilini

Nightly prices starting at
Mytilini holiday rentals start at €17 per night before taxes and fees

Verified guest reviews
Over 2,200 verified reviews to help you choose

Family-friendly holiday rentals
40 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 30 rentals that welcome pets

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wifi availability
100 of Mytilini holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Mytilini rentals

4.8 Average rating
Mytilini stays are highly rated by guests – averaging 4.8 out of 5!
Top-rated house rentals in Mytilini
Guests agree: these houses are highly rated for location, cleanliness and more.

Floras Charming Waterfront Villa
Flora's charming waterfront villa is located in the centre of the traditional picturesque village of Melinda, situated 6 km west of the village of Plomari. Our villa is situated literally on the beach, which is known for its crystal blue waters. The newly built modern house is fully equipped with all conveniences, such as a modern kitchen, air condition units in all rooms, tv, wi-fi etc. The famous traditional greek taverna of Maria is right next door, where you can enjoy local delicacies all day. In Our quiet villa you will experience greek at its summer, watching the sunset.
4.89 out of 5 average rating, 103 reviews
Kiki's house in the castle
Kiki's House is a comfortable space in the heart of the historic center of Mytilene, with a unique view of the Castle. The house can accommodate up to 5 guests, has 3 bedrooms, a spacious bright living room, a fully equipped kitchen, and a comfortable parking space. In the beautiful courtyard, you will enjoy moments of relaxation overlooking the historic walls of the castle. The property is ideal for families with children, couples, or groups looking for tranquility, comfort, and easy access to attractions.
5.0 out of 5 average rating, 4 reviews
Beautiful Plomari Cottage
Newly renovated, spacious and stylish house in a quiet street at the heart of Plomari is a perfect place for couples, groups and families of up to 6 people. It boasts an ultra-high ceiling with a lovely gallery. Fully equipped kitchen, dining area, bedroom and full bathroom on ground floor; additional bedroom, full bathroom, open space with a sofa-bed in the gallery. Amoudeli beach is a 250m stroll. Important note: for safety reasons, children under 12 years old are not allowed up at the gallery
4.92 out of 5 average rating, 26 reviews
Traditional Stone House in Seafront Olive Grove
A beautiful olive grove 55sqm stonebuild estate on the Greek island of Lesvos (Lesbos), in the embrace of the amazing Gera Gulf at the south-eastern part of the island. A shelter of harmony, calm and peacefulness, at the beachfront of the crystal clear blue waters of the gulf, where you can swim and relax under the olive and pine trees with a unique sense of privacy, only 10 minutes away from the central city, port and airport of Mytilene. Hosts 2 adults and up to 2 children
5.0 out of 5 average rating, 12 reviews
Aegean View Resort # The House
Tranquillity, relax and comfort best describe this house set in absolute nature in a peaceful suburb, only a few minutes away from the heart of the Mitilini. The property featuring stunning architectural details that provides guests with a high level of comfort and style but it can also be your base for exploring the rest of the beautiful and big island.It is perfect for families, couples or a group of friends looking for spacious areas, large terraces, comfort and privacy.
4.98 out of 5 average rating, 98 reviews
Pierres Blanches Residences 2
Discover the ultimate accommodation experience 1.5 km from the city center of Mytilene. With elegant design and modern amenities, our three autonomous detached houses, 120 sq.m. each, invite you to enjoy the tranquility and beauty of the island. Each villa has three comfortable bedrooms, two bathrooms, a spacious living room, an attic, a fully equipped kitchen and a private pool to cool off and enjoy the sun in the comfort of your own pool.
5.0 out of 5 average rating, 20 reviews
Ioanna's traditional house in the center of 140m2
Traditional building, built in 1880, in the historic city center. Renovated in 2008. It is aimed at lovers of authenticity, antiques and art! Ideal for a romantic vacation (the choice of honeymooners). It offers a comfortable stay for families with young children and babies! A 5-minute walk from the port and the beach, cafes, restaurants, bars, as well as most of the attractions of Mytilene! Children under 12 stay free of charge!
4.99 out of 5 average rating, 74 reviews
4 seasons
Fully furnished 38 sq.m. apartment, ideal for up to 2 guests — an ideal choice for couples or travelers seeking comfort and tranquility. The apartment is located in the traditional neighborhood of Synoikismos, very close to all local businesses (pharmacy, mini market, bakery, greengrocer, pastry shop, etc.) and just a few minutes away from the city center. It is an ideal choice for either a short getaway or a longer stay.
4.98 out of 5 average rating, 61 reviews
Iris Home
Our two-level recently renovated maisonette Iris Home is located in the city center. It has a fully equipped kitchen and dining area to enjoy your food with your family and friends overlooking the sea. The two bedrooms and the bathroom are on the lower level and continue the view of the endless blue of the Aegean Sea. Within a 2-minute walk, you can find the city's marina, restaurants, cafes and other shops.
4.98 out of 5 average rating, 41 reviews
PanDesSia
"PanDesSia" is a traditional house in Mytilene, with Lesbian architecture. It is located in "Kayani", close by the famous "Antonis" Ouzeri. Offers a veranda with a fantastic view of the Aegean Sea, the town and the harbor of Mytilene and the Turkish coasts. It is only 6km from the town of Mytilene and 4km from the airport. It has two bedrooms overlooking the sea and can accommodate at least 4 people.
4.82 out of 5 average rating, 116 reviews
Mytilene Luxury Villa | Garden level
Enjoy the private garden level apartment of our luxury villa with 3 bedrooms and panoramic views over Mytilene and the Aegean Sea. You’ll have a private entrance, exclusive use of the garden and outdoor areas, ensuring complete privacy. Just 5–7 minutes by car from Mytilene center, the port, and restaurants. Perfect for families and friends looking for comfort, style, and peace.
5.0 out of 5 average rating, 22 reviews
Pelagia's House
Pelagia's house is a seaside house that has been recently renovated while keeping its traditional character along with the memories of many carefree summers. The house has 2 bedrooms with one double and two single beds, a fully equipped kitchen, a very comfortable bathroom, air conditioning and wifi in all areas This seaside house is ideal for a quiet and relaxing vacation.
4.94 out of 5 average rating, 35 reviewsPopular amenities for house rentals in Mytilini
House rentals with a pool

Ouzo Traditional House with privatepool & parking
5.0 out of 5 average rating, 18 reviews
Twostorey house with amazing view (Aqua)
4.98 out of 5 average rating, 64 reviews
Galini Ducks
5.0 out of 5 average rating, 15 reviews
Eros' sea view Mytilini (A)
5.0 out of 5 average rating, 10 reviews
Tranquil Haven with private pool by Sea Sun
5.0 out of 5 average rating, 6 reviews
Ouzo Panoramic House 2A (3BR with private pool)
5.0 out of 5 average rating, 3 reviews
Eleia Villa with Private Pool and Sea View
4.96 out of 5 average rating, 23 reviews
Spacious Villa with Pool & Sea View in Cunda
New place to stayWeekly house rentals

Adalı beachfront retreat
4.95 out of 5 average rating, 21 reviews
the Workshop
4.89 out of 5 average rating, 18 reviews
Mcm Luxury & Traditional house
4.89 out of 5 average rating, 28 reviews
Perfect Beachfront Location
5.0 out of 5 average rating, 8 reviews
Casa De Pera Ermou
4.85 out of 5 average rating, 27 reviews
Detached house in the city center
4.93 out of 5 average rating, 27 reviews
Hidden gem checkpoint-Rodanthemo
4.77 out of 5 average rating, 26 reviews
Ambelos, Lesvos Beach House
5.0 out of 5 average rating, 30 reviewsPrivate house rentals

Modern house by the sea
4.96 out of 5 average rating, 28 reviews
Central Two-Storey Home with Private Yard
5.0 out of 5 average rating, 11 reviews
Villa with Sea View Bedroom in Yera Bay, Lesvos
4.94 out of 5 average rating, 18 reviews
D. Bernardaki Garden House
5.0 out of 5 average rating, 16 reviews
Seaside house amongst olive trees
4.98 out of 5 average rating, 54 reviews
Green House
4.9 out of 5 average rating, 30 reviews
House in olive grove close to the beach
4.91 out of 5 average rating, 58 reviews
Agiasos Classic Stone House
4.95 out of 5 average rating, 19 reviewsWhen is the best time to visit Mytilini?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | €61 | €59 | €60 | €71 | €81 | €84 | €78 | €91 | €72 | €65 | €64 | €63 |
| Avg. temp | 8°C | 9°C | 11°C | 15°C | 20°C | 25°C | 28°C | 28°C | 23°C | 19°C | 14°C | 10°C |





