
House holiday rentals in Mission Bay, San Diego
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Top-rated house rentals in Mission Bay, San Diego
Guests agree: these houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for house rentals in Mission Bay, San Diego
House rentals with a pool

3 BR Urban Oasis with Pool and Spa in Great Area

Private 3 bedroom block to Bay New Pool Spa, Bikes

Resort Style Living with Pool, Spa, and Bay Views!

Your Modern Lux Pool Resort in the Heart of SD

Luxurious North Park Home - Walk to Dining & Shops

Lionhead - Private Boutique Home

Centrally located Home w/Guest House, Pool & Spa!

University Heights Oasis Getaway
Weekly house rentals

Modern Central SD Home w/ Pool & Spa Near Beach

Bright & Modern OB Getaway

Luxury Two-Level Condo | Panoramic Ocean Views

The Mission on the Beach-Oceanfront Christian Home

Casa Luna: Charming Cottage | Walk to Ocean & Bay

Pacific Beach Beautiful Bayside Retreat with Bikes

New Listing! Beach House 2 bedroom, 3 beds

Cute Beach Bungalow
Private house rentals

Luxury Resort: Pool, Spa, Swim-Up Bar & Bay Views

Oceanfront Getaway 2/2 + Hot Tub

Modern Mission Beach Home w/ Ocean Views + Parking

New! Stunning Retreat Steps from Sunset Cliffs

Luxury Condo Mission Beach, 3BR/2BA, Steps to Sand

Ocean Beach Spanish Cottage with Ocean Views

Beach Cabin, Steps to Beach/Bay

NEW Modern Ocean View Home + Free Parking
Quick stats about house rentals in Mission Bay, San Diego
Total rentals
840 properties
Nightly prices starting at
€ 34 before taxes and fees
Total number of reviews
42K reviews
Family-friendly rentals
730 properties are a good fit for families
Pet-friendly rentals
270 properties allow pets
Rentals with a pool
10 properties have a pool
Destinations to explore
- Rentals with a beach view Mission Bay
- Rentals with a kayak Mission Bay
- Rentals with pools Mission Bay
- Pet-friendly rentals Mission Bay
- Apartment rentals Mission Bay
- Hotel rentals Mission Bay
- Rentals with breakfast Mission Bay
- Family-friendly rentals Mission Bay
- Guest house rentals Mission Bay
- Rentals with lake access Mission Bay
- Rentals with a hot tub Mission Bay
- Smoking-friendly rentals Mission Bay
- Rentals with beach access Mission Bay
- Beachfront rentals Mission Bay
- Rentals with a washing machine and dryer Mission Bay
- Flat rentals Mission Bay
- Townhouse rentals Mission Bay
- Cottage rentals Mission Bay
- Rentals with an EV charger Mission Bay
- Beach house rentals Mission Bay
- Rentals with a sauna Mission Bay
- Rentals with outdoor seating Mission Bay
- Family-friendly rentals Mission Bay
- Rentals with a firepit Mission Bay
- Rentals with a fireplace Mission Bay
- Fitness-friendly rentals Mission Bay
- Rentals with a patio Mission Bay
- Waterfront rentals Mission Bay
- House rentals San Diego
- House rentals San Diego County
- House rentals California
- House rentals United States
- Yurt Rentals United States
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- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Rosarito Beach
- Oceanside City Beach
- Belmont Park
- Torrey Pines State Beach
- Pacific Beach
- Tijuana Beach
- Coronado Beach
- San Clemente State Beach
- SeaWorld San Diego
- Oceanside Harbor
- San Onofre Beach
- Coronado Shores Beach
- University of California San Diego
- LEGOLAND California
- San Diego Zoo Safari Park
- Balboa Park
- Black's Beach
- Trestles Beach
- Pechanga Resort Casino
- Liberty Station
- Sesame Place San Diego
- Moonlight Beach
- Playas Los Buenos
- USS Midway Museum