
Hotel holiday rentals in Mission Bay
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Top-rated hotel rentals in Mission Bay
Guests agree: these hotel rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for hotel rentals in Mission Bay
Family-friendly hotel rentals

Stylish San Diego downtown Suite

Ocean Beach - Bed in a 8-Bed Mixed Dorm

Ocean Beach - Bed in 6-Bed Female Dorm

Clean 1 Bedroom San Diego-Poway

Ocean Beach - Bed in 6-Bed Mixed Room

Comic-Con 2025! Stay within walking distance!

Family Vacation! Close to SeaWorld! Onsite Pool!

Elegant SD Studio Suite | Kitchen, WiFi + Netflix
Hotel rentals with a pool

1-Bedroom Hotel Suite - 2 beds

Recently reno’d escape near the Gaslamp Quarter

Iconic Resort in San Diego

Vineyard Hacienda - 5 - Merlot

Playful escape near games & concerts at Petco Park

Downtown Hotel with Pool & Parking, Pets Allowed!

Free B’fast & Parking – Minutes to Pacific Beach

Spacious King Bed|Pool|Free Parking
Hotel rentals with a patio

Modern King Room | Luxe Stay in Little Italy

WorldMark Inn at the Park

Club Wyndham Harbour Lights

Queen Studio in Central Little Italy (Patio)

Comic-Con 2026: Spacious King Suite + Sofa Bed

2 bd/2 bth Resort Style Hotel

Nice Property, stay right in SD!

Worldmark Studio Sleeps 4
Destinations to explore
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- Rentals with pools Mission Bay
- Rentals with a patio Mission Bay
- Family-friendly rentals Mission Bay
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