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Holiday rentals in La Mesa

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Top-rated holiday rentals in La Mesa

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Top guest favourite
Guest house in Las Cruces
4.96 out of 5 average rating, 211 reviews

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Guest favourite
A room features a spacious bed dressed in white linens, complemented by a dark blue throw pillow. Natural light filters in through sheer curtains. A small table with a microwave and refrigerator is visible, along with a black rug on the floor and a fan in the corner.
Guest suite in Las Cruces
4.93 out of 5 average rating, 603 reviews

Tiny Cute Cubby in Telshor Hills, Private Entrance

The Cubby is perfect for overnight or short-term stays. Zero contact check-in and check-out. Access to central Las Cruces. Close to NMSU, Mesilla Valley Mall, major medical centers, and major event facilities. Located in Telshor Hills, a quiet neighborhood with plenty of mature trees and vegetation. Close proximity to observatory, minimal light pollution. Gorgeous views of Organ Mountains and Tortugas Mountain (A Mountain). Ten minute drive from historic Mesilla. Close to various hiking trails.

Top guest favourite
The living area features a blend of modern and artistic design, showcasing a leather sofa, a wicker chair, and a turquoise armchair. A wooden coffee table is centrally located, accompanied by a small side table. Natural light highlights the rich wood flooring and art on the walls.
Barn in Anthony
4.96 out of 5 average rating, 393 reviews

La Union Penthouse Apartment

Just remodeled and updated! Originally designed by Contemporary Artist, Willie Ray Parish. A huge, paradoxically cozy space, ideal for the traveling couple with a single Queen sized bed; it occupies approximately 1600 square feet on the top floor of a former cotton gin warehouse surrounded by a 2-acre Permaculture experiment. It is the private "Penthouse Apartment" amidst multiple communal and shared spaces on the property. Creative touches everywhere you look. A truly unique experience.

Top guest favourite
The kitchen features blue cabinetry and colorful Talavera tile backsplash, enhancing its visual appeal. A window allows natural light to illuminate the space, while stainless steel appliances, including a microwave and dishwasher, are present. Wood countertops provide a warm contrast to the cabinetry.
Guest house in Las Cruces
4.96 out of 5 average rating, 133 reviews

1 king bd with big fenced back yard pets welcome

Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

Top guest favourite
A vibrant yellow casita is framed by a rocky landscape and native vegetation. Large windows and a covered porch are visible, inviting natural light. The casita's exterior showcases a blend of rustic charm and modern design, set against a clear blue sky.
Guest house in Las Cruces
4.98 out of 5 average rating, 174 reviews

Raven's House

Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Guest favourite
A bright and airy living space features a blend of modern and vintage elements. A dining table is elegantly set with vibrant decor, while yellow accent chairs provide a pop of color. A cozy blue sofa is positioned nearby, alongside a window adorned with cheerful curtains.
Home in Mesilla Park
4.94 out of 5 average rating, 356 reviews

One bedroom casita in Mesilla Park with hot tub

This unique place has an ambiance all its own. Located a few minute drive from historic old Mesilla and walking distance to a local coffee shop, Mexican restaurant, and a pizza restaurant. Mesilla plaza, and bars are only a few minutes drive away. The building is fully renovated with stainless steel new appliances and dual refrigerated air mini splits, one in the living room, and one in the bedroom. Please note there is a train that occasionally travels near the neighborhood.

Top guest favourite
A bright interior features a queen bed adorned with geometric patterned bedding. Adjacent to the bed, two armchairs offer comfortable seating. A small loft area with a twin bed is visible overhead. A mirror and lamps provide additional lighting in the room.
Tiny home in La Mesa
4.97 out of 5 average rating, 190 reviews

Little House with Private Patio and Hot Tub

Our guesthouse is located on historic Highway 28, also known as the Don Juan de Onate Trail, which connects El Paso and Las Cruces. It is one of the area's most scenic routes. You can find breweries, multiple wineries, and the famous Chopes restaurant and bar along the route. The highlight of the 10-mile drive from our little house in San Miguel to historic Mesilla takes you through unique canopies of pecan trees, in the largest pecan-producing county in the nation.

Guest favourite
Home in Las Cruces
4.91 out of 5 average rating, 121 reviews

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV

Pecan Palace: luxe 4-BR near NMSU & White Sands. Tucked by pecan farms, this new retreat blends comfort + fun. Perfect for families, work trips, extended stays. ☞ EV charger ☞ Backyard hot tub under pergola ☞ Climate-controlled game lounge with pool table ☞ Foosball ☞ Poker ☞ Pac-Man ☞ Fully equipped chef's kitchen ☞ Plush bedrooms with blackout curtains ☞ Prime spot—1.5 mi to NMSU, Interstate I-10, dining & shopping ☞ Easy access to White Sands NP and downtown

Top guest favourite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guest house in Las Cruces
4.97 out of 5 average rating, 339 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top guest favourite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guest house in Las Cruces
4.99 out of 5 average rating, 197 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Guest favourite
A spacious living area features a large gray sectional sofa with decorative cushions. A wooden coffee table sits in front, while light fixtures illuminate the room. The kitchen area is visible in the background, showcasing white cabinets and a decorative tile backsplash.
Home in Las Cruces
4.89 out of 5 average rating, 270 reviews

4 Bedroom Contemporary Model home

This fully-furnished modern home is perfect for weekend getaways or longterm stays. With 4 bedrooms and plenty of space The Dove Escape offers the comfort of home with a luxury feel. This stylish modern space is perfect for families, groups, or anyone seeking a retreat at the end of long day in Las Cruces or a break from the road. The Dove escape is minutes from NMSU and the University Corridor with all it has to offer.

Top guest favourite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guest house in Las Cruces
4.99 out of 5 average rating, 200 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Popular amenities for La Mesa holiday rentals

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