
Holiday rentals in Doña Ana County
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Doña Ana County
Guests agree: these stays are highly rated for location, cleanliness and more.

Quaint casita for 2
*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Studio Casita 5 mins to Farmer's mkt/dogs welcome!
We welcome you to our cozy guest house in the heart of Downtown Las Cruces. Perfect for overnights with dogs or kiddos! Close to shopping, the Farmer's Market, and centrally located to enjoy all Las Cruces has to offer. You will have a private entrance, off-street parking, and a fenced yard to yourself. There is a queen bed and a pack-n-play as requested. There is a small kitchenette with a fridge, microwave, sm hot plate, and sink and the casita is equipped with utensils and the basics for you.

Tiny Cute Cubby in Telshor Hills, Private Entrance
The Cubby is perfect for overnight or short-term stays. Zero contact check-in and check-out. Access to central Las Cruces. Close to NMSU, Mesilla Valley Mall, major medical centers, and major event facilities. Located in Telshor Hills, a quiet neighborhood with plenty of mature trees and vegetation. Close proximity to observatory, minimal light pollution. Gorgeous views of Organ Mountains and Tortugas Mountain (A Mountain). Ten minute drive from historic Mesilla. Close to various hiking trails.

Bonita Casita
This is a centrally located, remodeled 2 bedroom, 2 bathroom townhouse, very convenient to HWY 70, a straight shot to White Sands National Park, and Main Street, easy access to Downtown Las Cruces, home to Las Cruces's Farmer's Market. This townhouse features a split and open floor plan, full kitchen with everything you need to prepare a meal, dishwasher, microwave and gas cooking. You will also find an office and outdoor seating area. The property is located very near the lovely 4-Hills Park.

Luxury Southwest Retreat
Our home provides comfort, relaxation, and convenience in an invitingly decorated setting. Three rooms offer various sleeping arrangements to meet all of your needs. Choose from a king, queen, or twin beds. Fully equipped and thoughtfully appointed kitchen provides for all of your meal needs. Luxurious backyard with Adirondack chairs, gas fire pit, porch rocking chairs, and outdoor dining set allow for relaxing and socializing. Washer & dryer available, detergent and fabric softener provided.

Casita on the Camino Real.
Cozy 260 sq. ft. studio apartment that can accommodate two adults Comfortable queen bed Large closet Kitchenette includes mini fridge, microwave, toaster oven, crock pot, rice cooker, French press, bar sink, cooking utensils and complete dinner service Full bath with tub Small dining table and chairs inside Wi-Fi Radio clock & USB ports Wall unit that is both AC and heat Small outside sitting area with seating and small outdoor kitchen with grill Off street parking Coded door entrance

Raven's House
Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Desert Peaks Casita
This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Cozy Casita w/private patio near Old Mesilla
This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Yucca Casita in Historic Mesilla
Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Cozy Casita De Mesilla (Mesilla Cottage)
Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Rustic Downtown Hideaway
This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.
Popular amenities for Doña Ana County holiday rentals
Other great holiday rentals in Doña Ana County

Mi Casa Su Casa-Charming Cozy & private w patio

Comfy room in spacious house shared bathroom, A

Modern,Clean Quiet Room

Home with large office space.

Nancy's Casita Talavera

Great for Traveling Professional! Clean and Cozy!

Spanish style, private room, close to I-10 twin

Mesilla Traveler's Choice Easy on/off to I-10
Destinations to explore
- Guest house rentals Doña Ana County
- Fitness-friendly rentals Doña Ana County
- Rentals with outdoor seating Doña Ana County
- Rentals with a washing machine and dryer Doña Ana County
- Rentals with a hot tub Doña Ana County
- Rentals with a firepit Doña Ana County
- Townhouse rentals Doña Ana County
- Rentals with a fireplace Doña Ana County
- Rentals with breakfast Doña Ana County
- House rentals Doña Ana County
- Private suite rentals Doña Ana County
- Rentals with pools Doña Ana County
- Tiny house rentals Doña Ana County
- Rentals with a patio Doña Ana County
- Pet-friendly rentals Doña Ana County
- Hotel rooms Doña Ana County
- Apartment rentals Doña Ana County
- Family-friendly rentals Doña Ana County
- Flat rentals Doña Ana County




