Hotels in Key West

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Top-rated hotels in Key West

Guests agree: these hotels are highly rated for location, cleanliness and more.

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Guest favourite
Santa Maria Suites
4.88 out of 5 average rating, 25 reviews

Santa Maria Suites

Enjoy the tropical landscape & magnificent pool views while relaxing on your spacious patio or balcony. Indulge in 960+ sq. ft. of open design interior space with luxury modern finishes. Includes two separate bedrooms w/ king-sized pillow-top beds & separate spa-inspired bathrooms w/ rainfall showers. A bright/airy living room comes equipped w/ a queen-size sleeper sofa, a separate laundry closet w/ a washer and dryer, & a fully equipped kitchen. Some of our Flat suites require the use of stairs

Guest favourite
Hotel room in Key West
4.88 out of 5 average rating, 674 reviews

The Sanchez House Room #3

There is no better welcome to Key West than staying in local and famous folk artist Mario Sanchez's birth home. This home was built in the 1860's in the heart of the historic Gato and Merrero cigar factory villages. Featuring original Dade County pine construction, and located right on historic Duval Street, the Sanchez House is guaranteed to offer the historic atmosphere and living a part of Key West many visitors want to experience. Sit on the balcony and enjoy the trade winds & Ocean Breeze.

Guest favourite
A well-appointed room features a spacious bed adorned with colorful pillows. Large windows with decorative glass let in natural light, illuminating the warm yellow walls. A flat-screen TV and stylish furniture create a cozy atmosphere, while decorative artwork enhances the aesthetic appeal.
Hotel room in Key West
4.98 out of 5 average rating, 40 reviews

Marrero's Guest Mansion Adult Only (21+) Room 6

Adult Only Boutique Hotel (21+). Experience the grandeur of the stately Victorian home, thoughtfully updated and lovingly converted into a boutique hotel. This room features one king bed and a full private bath located on the second floor of the mansion. This room is home to the largest veranda in the house and provides guests with a fantastic view of Fleming Street - perfect for relaxing, people watching, or enjoying a drink as you unwind. Also features a room with closet for extra storage.

Guest favourite
Hotel room in Key West
5 out of 5 average rating, 6 reviews

Steps to Duval St + Free Breakfast, Pool & Spa

Located at the quiet end of Duval Street, The Guesthouses at Southernmost Beach Resort offer an adult-focused sanctuary with a sophisticated Key West vibe. Guests enjoy "stay at one, play at all" access to the entire resort, including 3 pools, a private beach, and oceanfront bars. Walk to the Southernmost Point or relax in lush tropical gardens. Highlights include the beach-chic decor, world-class spa, and daily breakfast, blending boutique intimacy with full-scale luxury amenities.

Guest favourite
A well-lit bedroom features a spacious bed with a light-colored quilt, complemented by two bedside tables with orange lamps. French doors open to a balcony overlooking lush greenery. A light blue wall adds a calm touch, while a white wicker chair is positioned near the window.
Hotel room in Key West
5 out of 5 average rating, 20 reviews

Aquamarine Deluxe King

***21 and up*** Enjoy this charming hotel located 2 blocks from the Historic Wharf and 4 blocks to Duval St. This room is just steps away from our main pool, and appointed with a king bed with a walk in shower, Keurig coffee maker, TV, patio, and mini fridge. Perfect romantic getaway for 2! It shares a small patio with the neighboring room. Our property sports 2 pools, lush gardens, sitting areas, complimentary breakfast, and all the amenities you would need to enjoy Key West!

The resort’s exterior is presented with white wooden siding and a classic rooftop structure. Palm trees frame the view, emphasizing the tropical environment. Expansive balconies with white railings offer a welcoming aesthetic, while large windows allow natural light to illuminate the interior.
Hotel room in Key West
4.91 out of 5 average rating, 23 reviews

Luxurious Stay | Snorkeling. Outdoor Pool

Poised on the islands famous harbor, The Marker Key West Resort is a fresh approach to luxury, seamlessly blending the elegance of classic Florida Keys resorts with an air of modern glamor. Attractions nearby: ✔Mallory Square, once anchorage of pirates ✔Snorkeling ✔Butterflies & exotic birds at the Butterfly and Nature Conservatory ✔Amazing views for the top of the Lighthouse Museum ✔Southernmost Point Buoy, lowest latitude land of contiguous North American states

Top guest favourite
Hotel room in Key West
5 out of 5 average rating, 29 reviews

2BR Suite with 1.5 Bathrooms at The Key West Hotel

Welcome to The Key West Hotel—ideally located on Duval Street yet tucked away in a private oasis. Choose from charming rooms in a restored Victorian conch house or a modern poolside retreat, all surrounding a lush courtyard and sparkling pool. Guests can unwind at the exclusive Bali Bar, a tiki-style hideaway serving handcrafted island cocktails with live local music each night. It’s the perfect blend of relaxation and Key West energy. This room has 1.5 bathrooms.

Superhost
The living area features a Murphy bed within a dark wooden cabinet, a modern black sofa, and a wooden coffee table. A flat-screen television is positioned on a side cabinet. Natural light enters through sliding glass doors that lead to a private balcony.
Hotel room in Marathon
4.73 out of 5 average rating, 88 reviews

Knight's Key Suites Premium Apartment w/Kitchen

One-of-a-kind place accommodations located next to the 7-Mile Bridge in the heart of the Florida Keys. This room features one king, one queen, and one Murphy bed that can accommodate up to six people. full kitchen. Dear guest, we’re sorry to inform you that, due to unexpected circumstances beyond our control, the pool will be closed until Saturday 6/1/26. A significant leak was found and emergency repairs are necessary to fix the problem.

Superhost
Hotel room in Key West

Steps from the Beach + Free Shuttle & Pool

Experience the vibrant spirit of Cuba in the heart of Key West at Havana Cabana, a waterfront retreat full of charm and character. Classic cars, refreshing mojitos, and lively poolside music set the tone for a nostalgic escape inspired by Cuban art and culture. From the moment you arrive, vintage cars shine in the Florida sun while Flamenco rhythms and the scent of hand‑rolled cigars welcome you into an atmosphere that feels worlds away.

Superhost
Hotel room in Islamorada
5 out of 5 average rating, 3 reviews

Ideal Mix of Comfort & Value! Free Parking/ Pool

Escape to Amara Cay Resort in Islamorada, where breezy island flair meets boutique elegance. Enjoy private beach access, zero-entry pool with hammocks, and coastal-chic rooms with balconies. Explore kayaking, snorkeling, or hop a water taxi for dining across sister resorts—ideal for couples, families, or relaxed getaways.

Superhost
A well-lit guest room features a spacious bed with soft pillows and colorful decorative cushion. Nightstands with lamps are positioned on either side. A mirror and a small refrigerator are visible, along with a warm wood-paneled accent wall.
Hotel room in Key West
4.97 out of 5 average rating, 30 reviews

King Room (Limited Pet Friendly Rooms)

A beautiful Historic Hotel . More like a B&B . Our room was clean and bright with amenities . Great to have bike rentals on the property . I rode around the whole island. I’ve worked at hotels my entire life . The Palms is a great place to stay!

Ridley House - Key West Historic Inns
4.93 out of 5 average rating, 14 reviews

Ridley House - Key West Historic Inns

Enjoy the signature king, offering a plush king bed, breakfast, air conditioning, refrigerator, yoga mats, tv, wifi, a private bathroom with robes, and pet-friendly comfort. Perfect for relaxing after exploring Key West's historic sights.

Popular amenities for Key West hotels

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Quick stats about hotels in Key West

  • Total holiday rentals

    Explore 360 holiday rentals in Key West

  • Nightly prices starting at

    Key West holiday rentals start at € 145 per night before taxes and fees

  • Verified guest reviews

    Over 3,950 verified reviews to help you choose

  • Family-friendly holiday rentals

    70 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 110 rentals that welcome pets

  • Holiday rentals with a pool

    360 properties feature pools

  • Rentals with dedicated workspaces

    160 properties have a dedicated workspace

  • Wifi availability

    360 of Key West holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Key West rentals

  • 4.6 Average rating

    Key West stays receive an average rating of 4.6 out of 5 from guests

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