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Holiday rentals in Isla Grande

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Top-rated holiday rentals in Isla Grande

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Two rustic-style cabins are set along the shoreline, surrounded by lush tropical trees. A wide patio is furnished with colorful chairs, offering views of the water. The natural beauty of the landscape is complemented by the tranquil waves gently lapping at the shore.
Home in La Guaira
4.97 out of 5 average rating, 113 reviews

Puntita Manzanillo, fantastic sea and jungle

Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Superhost
Home in Isla Grande
5 out of 5 average rating, 3 reviews

Beachfront House + Kitchen + Balcony + AC + Wi-Fi @ Isla Grande

✔️SuperAnfitrión Verificado ¡Tu estadía estará en las mejores manos! 🚨Envíanos un mensaje con la palabra DESCUENTO y pregunta por promociones especiales 📍 Apartamento en Isla Grande, Provincia de Colon, Panamá 🇵🇦 🏡 Espacio limpio, cómodo y seguro, con excelente ubicación 🧼 Dotado con insumos y productos de limpieza Durante tu reserva, tu Airbnb cuenta con: 🌐Wifi 📺TV 🍳Cocina 🌊Frente al mar ❄️A/C 🚗Parqueo 👉Envíanos un mensaje con la palabra DESCUENTO y pregunta por promociones

Superhost
The image captures a serene beach scene featuring a sandy shoreline and clear turquoise waters. Thatched-roof gazebos are visible near the water, alongside a wooden pier extending into the sea. Various boats are moored in the distance, surrounded by tropical greenery.
Holiday home in Maria Chiquita
4.87 out of 5 average rating, 87 reviews

Dreamy, Modern Caribbean Home at Playa Escondida

Have fun with the whole family at Casa Capri, a dreamy place which is a perfect fit both for adults & kids. The apartment is at Playa Escondida, a stylish resort with white sand beaches and crystal clear ocean water, several amenities such as a restaurant (with a broad range of great food, including fresh seafood and sushi!), pools to chill or swim, plus fantastic and diverse children playgrounds. Whether you'd like to have a resting vacation or a fun getaway, Casa Capri got you covered. Enjoy!

Guest favourite
Serene waters reflect vibrant greens and blues, surrounded by lush vegetation. Two sailboats are anchored nearby a rustic hut, offering a glimpse of a tranquil lagoon. The distant hills cradle the scene, enhancing a connection with the natural landscape.
Home in Portobelo
5 out of 5 average rating, 15 reviews

AeolusGuestHouse Home in Portobelo National Park

Welcome to AeolusGuestHouse, a hidden retreat in Jose del Mar, inside the Portobelo National Park. Surrounded by protected jungle, mangroves, and calm lagoon. Ideal for disconnecting in nature. Kayaks are available, and boats pick you up at the dock in front of the house for local tours, including Venas Azules just 15 minutes away. The home offers 2 bedrooms, 4 beds, an equipped kitchen, AC, parking, and helpful hosts always ready to assist. Pure nature, zero crowds, unforgettable stays.

Superhost
Home in La Guaira
4.73 out of 5 average rating, 37 reviews

Bella Casa, Caribbean Sea, Juan Gallego (waterfront)

Hermosa Casa de Playa, frente al mar caribe, para descansar y relajarse al 100%. La Casa cuenta con una ubicación privilegiada, mantiene 4 habitaciones (una de ellas cuenta con una mampara para dividir de la sala y ampliar esa área en caso que se desee), sala, comedor, terraza privada, frente a Isla Grande. 4 habitaciones. 3 tienen TV con cable y una TV extra en la sala. Todas con con Aire Acondicionado. Cuenta con 2 baños completos. Cocina equipada y lista para disfrutar y Wifi

Top guest favourite
An inviting infinity pool overlooks a stunning coastal view. A spacious seating area, featuring colorful cushions, complements the serene atmosphere. Natural light fills the space, enhancing the connection to the outdoors, while the blue waters of the pool blend seamlessly with the distant ocean.
Villa in Cacique
4.98 out of 5 average rating, 57 reviews

FACING THE SEA Cacique (Portobello Park)

A house! A real glass island in the heart of the jungle! In the middle of the Portobello National Park (access only by 4x4 AWD) nestled at the top of the hill, between sky/sea, away from all eyes, a transparent house where glass embraces nature on all sides creating a unique connection between the inside and the outside, ideal for resting, disconnecting, comfortable, spacious, cool (central air conditioning), exclusive. It is the witness of a grandiose spectacle that awaits you!

Guest favourite
A serene swimming pool is depicted surrounded by lush palm trees, with the tranquil sea visible in the background. The water's clear blue tiles reflect the sky and nearby greenery, while the gentle curvature of the pool edge invites relaxation.
Villa in Portobelo
4.97 out of 5 average rating, 86 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Guest favourite
The two-story house is positioned just steps from the water's edge, surrounded by lush greenery and palm trees. A spacious terrace extends from the upper floor, providing a view of the serene landscape. The natural stone shoreline complements the tranquil setting.
Flat in Colón
4.94 out of 5 average rating, 111 reviews

KasaKai garden floor - amazing views over the sea

Caribbean downstairs apartment with amazing sea view. Surrounded by wildlife. This property has a private access to the Caribbean Sea. The house is situated over a 2 miles long reef. Amazing snorkeling, there are many naturals pools into the reef where you can snorkel. Ideal for kids! There is a jungle behind the house which makes that you will hear the monkey from the house.

Top guest favourite
Home in Maria Chiquita
4.98 out of 5 average rating, 46 reviews

‘Beautiful and Comfortable Villa at Playa Escondida Resort’

Luxury Resorts y Villa, front lagoon view y playa solamente a 2min, Disfruta de una estadía cómoda y tranquila en este alojamiento totalmente equipado, ideal para matrimonios, familias, grupos pequeños o viajeros de negocios. Tiene capacidad para hasta 6 huéspedes, ofreciendo un ambiente acogedor, limpio y funcional,una terraza amplia,sin duda para una estancia agradable,

Superhost
An outdoor seating area is presented with four woven chairs positioned around a rectangular table. The view reveals a serene sea in the background, with a well-kept grassy area and scattered rocks leading to the water's edge. Bright sunlight enhances the peaceful atmosphere.
Home in La Guaira
4.69 out of 5 average rating, 180 reviews

Casa "El Terrenito" - Ocean Front

Spacious waterfront house with 2 bedrooms, one room with 3 queen beds and 2nd with a king and a twin. Kitchen, living room, dining room. It has all the utensils for kitchen, sheets, stove,refrigerator, A/C. Special to relax!! For fishing fans we can provide a fishing panga! Additional price per day and captain. You can bring a pet.

Superhost
An aerial view captures a serene bay bordered by lush tropical greenery. A small boat is anchored in the clear waters, and a spacious house is situated near the beach, surrounded by trees and open land, creating a harmonious natural setting.
Home in Playa Blanca
4.76 out of 5 average rating, 79 reviews

Sparrow's Point

Un lugar paradisiaco que muestra al caribe panameño en su mejor esplendor!! La playa de arena blanca protegida por una bahía de aguas cristalinas y enmarcada por la selva tropical crean un idílico contraste entre el verde del follaje y el azul de la laguna. Despierte a 10 pasos del mar.

Guest favourite
A tranquil view of modern villas stretches alongside a large swimming pool, featuring clear blue water that reflects the sky. Lush greenery borders the pool area, contributing to a serene atmosphere. The elegant architecture of the villas is complemented by a backdrop of peaceful clouds.
Villa in Maria Chiquita
4.85 out of 5 average rating, 142 reviews

Enjoy a spectacular Villa in Playa Escondida

Playa Escondida Resort & Marina is a jewel of the Caribbean, one of the most beautiful and exclusive beaches, one hour from Panama City, located in Maria Chiquita, Colón. Our exclusive Villa has a natural Jacuzzi on the terrace with access to the pool and a 1-minute walk to the beach.

Popular amenities for Isla Grande holiday rentals

Frequently Asked Questions

  • Where is Isla Grande located?

    Isla Grande is situated just off Panama's northern Caribbean coast, in Colón Province. It is found near the entrance to the Portobelo National Park area, surrounded by tropical waters and natural scenery.

  • When is the best time to visit Isla Grande?

    Travelers frequently suggest visiting Isla Grande during the dry season for clearer skies and calmer seas. The rainy months bring lush landscapes and a quieter atmosphere, with both offering distinct ways to experience the island.

  • What are some things to do near Isla Grande?

    You can explore sandy beaches, snorkel around coral reefs, and experience local seafood restaurants on Isla Grande. The island also has relaxed walking paths and is known for welcoming Afro-Caribbean cultural influences and music.

  • How is the weather near Isla Grande?

    Isla Grande typically has a warm, humid tropical climate year-round, with temperatures often between 77 and 88°F (25 and 31°C). Rain is common outside of the dry season, and brief showers can occur throughout the year.

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