Guest house holiday rentals in Great Smoky Mountains
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Great Smoky Mountains
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Great Smoky Mountains
Family-friendly guest house rentals
Guest house in Waynesville
4.96 out of 5 average rating, 257 reviewsCozy studio loft in the Blue Ridge Mountains
21–28 May
Guest house in Sevierville
4.97 out of 5 average rating, 327 reviewsButterfly Barn in the Smoky Mountains
7–14 Jul
Guest house in Maryville
4.98 out of 5 average rating, 246 reviewsLaLa’s Place a cottage over the 100yr old bridge
30 Jun – 7 Jul
Guest house in Cosby
4.9 out of 5 average rating, 256 reviewsThe Birdhouse - A quiet country apartment In Cosby
25 Nov – 2 Dec
Guest house in Sylva
4.94 out of 5 average rating, 299 reviewsAmazing view! Heart of All Things Smokies Near WCU
3–10 Mar
Guest house in Leicester
4.92 out of 5 average rating, 286 reviewsRelax by the creek. 10 Min. to West Asheville
29 Jul – 5 Aug
Guest house in Candler
4.97 out of 5 average rating, 448 reviewsThe Cottage at Maple Hill
30 Jan – 6 Feb
Guest house in Knoxville
4.98 out of 5 average rating, 515 reviewsTreeHouse Haven, Very Private, Great Location
19–26 Jul
Guest house rentals with a patio
Guest house in Knoxville
4.96 out of 5 average rating, 117 reviewsThe Chicken Coop city meets country in a cozy spot
23 Feb – 2 Mar
Guest house in New Market
4.87 out of 5 average rating, 107 reviewsRest & Relax at our Rustic Retreat!
23–30 Jun
Guest house in Maggie Valley
4.98 out of 5 average rating, 96 reviewsSpectacular Great Smokey Mountains Views
10–17 Dec
Guest house in Townsend
4.96 out of 5 average rating, 85 reviewsSmoky Mountain studio with alfresco dining.
29 Oct – 5 Nov
Guest house in Tallassee
4.96 out of 5 average rating, 71 reviewsIntimate 1-bedroom guesthouse with private hot tub
2–9 Aug
Guest house in Sylva
4.98 out of 5 average rating, 66 reviewsThe Woodlen: Studio with Views/Hot tub/ fire pit
4–11 Jun
Guest house in Sevierville
4.89 out of 5 average rating, 74 reviewsThe Black Wolf Lodge (Close to parkway)
16–23 Aug
Guest house in Andrews
4.97 out of 5 average rating, 33 reviewsThe Bird’s Nest Cottage Retreat
13–20 Aug
Guest house rentals with a washing machine and dryer
Guest house in Whittier
4.94 out of 5 average rating, 234 reviewsNature's Nest
2–9 Oct
Guest house in Franklin
4.97 out of 5 average rating, 203 reviewsThe Franklin Carriage House
16–23 Aug
Guest house in Maryville
5.0 out of 5 average rating, 117 reviewsLittle River Guesthouse at Wildwood Rd.
4–11 Oct
Guest house in Newport
4.99 out of 5 average rating, 185 reviewsMountain View Guesthouse
14–21 Sep
Guest house in Waynesville
4.96 out of 5 average rating, 159 reviewsThe Getaway
14–21 Jul
Guest house in Maryville
4.94 out of 5 average rating, 146 reviewsRelax in a Smoky Mtn getaway near Knoxville
8–15 Feb
Guest house in Canton
4.98 out of 5 average rating, 187 reviewsClean, cozy & kid-friendly in mountains of WNC
3–10 Jun
Guest house in Sevierville
4.89 out of 5 average rating, 306 reviews5 mins to Dollywood! Dog stays free in 2024!
6–13 Jul
Destinations to explore
- Guest house rentals United States
- House rentals United States
- Rentals with a hot tub Great Smoky Mountains
- Lakehouse rentals Great Smoky Mountains
- Cabin rentals Great Smoky Mountains
- Bed and breakfasts Great Smoky Mountains
- Rentals with a patio Great Smoky Mountains
- Pet-friendly rentals Great Smoky Mountains
- Rentals with a cinema Great Smoky Mountains
- Tiny house rentals Great Smoky Mountains
- Smoking-friendly rentals Great Smoky Mountains
- Rentals with a kayak Great Smoky Mountains
- Rentals with lake access Great Smoky Mountains
- Rentals with an accessible-height toilet Great Smoky Mountains
- Rentals with a fireplace Great Smoky Mountains
- Cottage rentals Great Smoky Mountains
- Rentals with a washing machine and dryer Great Smoky Mountains
- Villa rentals Great Smoky Mountains
- Hotel rentals Great Smoky Mountains
- Rentals with a firepit Great Smoky Mountains
- Monthly Rentals Great Smoky Mountains
- Loft rentals Great Smoky Mountains
- Waterfront rentals Great Smoky Mountains
- Wheelchair-accessible rentals Great Smoky Mountains
- Apartment rentals Great Smoky Mountains
- Private suite rentals Great Smoky Mountains
- Rentals with an EV charger Great Smoky Mountains
- Family-friendly rentals Great Smoky Mountains
- House rentals Great Smoky Mountains
- Rentals with breakfast Great Smoky Mountains
- Boutique hotel rentals Great Smoky Mountains
- Fitness-friendly rentals Great Smoky Mountains
- Rentals with pools Great Smoky Mountains
- Rentals with outdoor seating Great Smoky Mountains
- Flat rentals Great Smoky Mountains
- Farm stay rentals Great Smoky Mountains
- Rentals with a sauna Great Smoky Mountains
- Holiday home rentals Great Smoky Mountains
- Rentals with an accessible-height bed Great Smoky Mountains
- Chalet rentals Great Smoky Mountains
- Family-friendly rentals Great Smoky Mountains
- Campsite rentals Great Smoky Mountains
- Townhouse rentals Great Smoky Mountains
- House rentals Gatlinburg
- Guest house rentals Asheville
- House rentals Asheville
- House rentals Pigeon Forge
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom