Waterfront holiday rentals in Cape Girardeau County

Ace Of Hearts- 1 Bed 1 Bath

Directly across the street from Century Casino, this 1 Bed- 1 Bath home sleeps 2. Perfect for a weekend away or an elevated stay when traveling for work. Completely remodeled, be one of the first to stay in this iconic home that was built in the 1930's to house factory workers from the historical red star shoe company. Stylish interior and an exterior view like no other, sip your coffee in style. Enjoy cooking in a full kitchen or take a walk downtown to enjoy beautiful shops and restaurants.

Lorimier Loft Gallery next to SEMO River Campus

Directly across from Southeast Missouri State University’s River Campus, Lorimier Loft Gallery features luxury accommodations, purchasable gallery artwork and easy access to historic downtown Cape Girardeau. Every inch of this space delivers an aesthetic experience from the artwork to the tile-work to the location: Cross the street for performing art at the River Campus. Sit on the porch and listen to the marching band practice. Curl up by the fire and soak in a rich gallery during your stay.

River Run

Charming 1940s farmhouse. Updated 1 1/2 story house in a rural setting overlooking the Mighty Mississippi River, but close to the heart of Cape Girardeau. Our house has lots of room to relax with a large kitchen and sunroom. You can sit by a cozy fire pit and enjoy chilly evenings watching the beautiful sunsets. We look forward to you spending time in our neck of the woods (so to speak). We are located with in seven miles from the Isle casino, SEMO state university and a happening down town.

Twisted Sassafras Treehouse

A custom-built treehouse located on 10 acres with a water view that you can take in from the hot tub on the deck! It is nestled high in the trees and is the perfect romantic getaway for two! Feel like you are away from it all without being away from it all! This treehouse is located on a county road just minutes from Cape Girardeau. Enjoy catch and release fishing on site, local wineries, shopping in historic downtown Cape Girardeau, local restaurants, gambling, historical sites & more!

Apple Creek Loft

Make some memories at this unique and family-friendly place. Enjoy what many remember to be the Old Store in Old Appleton. Have a peaceful experience near the Historic Bridge spanning the Apple Creek waterfall. Enjoy kayaking, fishing, and swimming in the creek right outside your door. This destination has beds to accommodate 6 people. Plus, there is a spacious living room and master bedroom where more guests could sleep if they would like to bring an air mattress/sleeping bag.

The Outlook - Private Balcony

Welcome to 115 N Water, Unit 103 in Cape Girardeau, MO! This delightful property not only offers a cozy retreat but also boasts a private balcony with stunning, unobstructed views of the Mighty Mississippi River. Perfectly situated close to downtown, it's just steps away from a vibrant nightlife scene, with numerous bars and restaurants for an unforgettable date night experience. Enjoy the best of both worlds – scenic beauty and lively entertainment – right at your doorstep!

Downtown Condo on the River

Located in the heart of downtown Cape Girardeau, this furnished condo features a view of the Mississippi River & Emerson bridge from every window. A historic gem with all of today's modern amenities. This unique building has a private covered parking garage. A perfect place to get away and sit out on the deck overlooking the river while you BBQ, or just enjoy the river and relax.

Lucky Queen- 4-bedroom Steps away from the Casino

Directly across the street from Century Casino. This 4 Bedroom, 2 Bath home is PERFECT for larger groups staying together. Completely remodeled with design touches that highlight all of Cape Girardeau's wonderful history. Each Bedroom has a queen bed with a large closet. Master Bedroom offers its own private full bath. Plenty of parking and private fenced in back yard!

The Cabins 1

You won’t forget the peaceful surroundings of this rustic destination. Get back to the simpler things in life. Relax and unwind on the covered porch or around a fire pit by the pond. Plenty of attractions to see, local places to eat along with numerous outdoor activities. All within 20-30 minutes. The good life is waiting for you!