
Holiday rentals in Santa Clara
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Santa Clara
Guests agree: these stays are highly rated for location, cleanliness and more.

Private property near the city | Exclusive use
Enjoy Finca Los Caobos exclusively, surrounded by nature and just a few minutes from the city Ideal for private family gatherings, intimate celebrations, and special get-togethers, the property features 3 bedrooms, spacious green areas, a pool, and peaceful spaces to relax and share meaningful moments Perfect for guests looking for privacy, comfort, and a relaxed atmosphere Private family gatherings may be considered with prior agreementAny additional activity must be disclosed before booking

Casa Condal - Your Luxury Retreat in Cerro Azul
Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Beach House-Amazing Pool & Jacuzzi - Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

The Hidden Gem
Here you will find your home away from home in this hidden gem. Furnished with all of the creature comforts, you will have plenty to do from relaxing on the patio while listening to music, to taking a dip in the heated pool, to relaxing on the comfy couch and watching Netflix. The house is situated on a beautiful gated beach property where you can find various activities from kayaking to the local water park. You can find the relaxation you were searching for here in this hidden gem.

Modern House with Great Views and Heated Pool
Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

The Crystal House: Luxury Modern Wood Cabin
Crea recuerdos inolvidables en este alojamiento único e ideal para familias. Quédate en una cabaña en medio del Parque Nacional Chagres a 50 minutos de la ciudad. Podrás estar en contacto con la naturaleza contando con todas las comodidades de un alojamiento de lujo. Con una de las mejores vistas a la ciudad puedes disfrutar de una buena barbacoa, una siesta en la hamaca o una reunión alrededor de la chimenea. Relájate y conéctate con el lindo verde de Panamá. Te esperamos!

GreatCanal-Front Luxury 3BR | City & Golf View 401
Welcome to Palash Tower — a rare canal-front gem! Experience luxury in this spacious 3-bedroom, 3-bath apartment set on a 74-hectare gated golf estate. Enjoy panoramic skyline and canal views where ships pass through the lock below. Relax at the rooftop infinity pool, gym, spa, and on-site restaurants. Free parking and 24/7 security included. The only place where the city meets the water and golf in perfect harmony. Minutes from the City Center and Historic Casco Viejo.

Chagres River Lodge
You stay in our guest house on the River Chagres, in the village Santa Rosa. it is a stone house with a beautiful Panama rancho over it, so the house stays nice and cool. In our garden you have large trees with many birds such as parrots. We have a sloth in the tree. In the morning you can hear the monkeys on the other side and you can explore the area with the canoe. Or take a dip in the river to cool off. A boat to Gamboa or the Panama Canal is a 20 minute boat ride.

Villa Acuario
Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.

Tropical Haven with Pickleball/Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Cerro Azul Mountain Retreat a magical home.
Enjoy every corner and luxury in this spacious house with 6 rooms with airs and 6 bathrooms. The perfect terrace to relax outdoors, while the ideal dining room to share special moments with your loved ones. The greenhouse is an oasis of fresh ingredients, ready to inspire delights. We have a new deck and jacuzzi ready to enjoy allowing you to connect with nature and beautiful sunsets. It has a game room, soccer pool table and a/ac
Popular amenities for Santa Clara holiday rentals
Other great holiday rentals in Santa Clara

Luxury beachfront villa!

Most Beautiful Loft in the Heart of Casco Viejo

La Florecita - Country house in Valle de Antón

House in Costa Verde, West Panama

Tiny Cabin | Cerro Azul - Cabin I

The Bird's Nest in the Clouds

Roca de Toscana Lodge - Altos del Maria

Spectacular ocean view, private beach access, pool
Destinations to explore
- Panama City Holiday rentals
- Cahuita Holiday rentals
- Bahía Ballena Holiday rentals
- Coveñas Holiday rentals
- Puerto Viejo de Talamanca Holiday rentals
- Bocas del Toro Province Holiday rentals
- Uvita Holiday rentals
- Boquete Holiday rentals
- San Andrés Holiday rentals
- Rio Hato Holiday rentals
- El Valle Holiday rentals
- Cartago Holiday rentals





