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Holiday rentals in Santa Clara

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Clara

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A small, rustic structure is positioned amidst a lush, mountainous landscape. A winding gravel road leads towards the building, surrounded by greenery, hills, and trees. The scene is softly illuminated by sunlight, highlighting the natural setting and open space.
Shipping container in San Carlos
4.99 out of 5 average rating, 70 reviews

Justinatinyhouse disconnects to connect

Justinatinyhouse is nestled in the foothills of the San Carlos Lagoon. It has everything you need for your stay with a lot of peace, a cool breeze in the mornings and afternoons, incredible views towards Altos del María, Sorá, Punta Chame, and a dirt road in good condition for any car. It has A/C and everything you need for your stay. It does not have a TV, but there is excellent cell phone coverage. I recommend bringing all the things you need for your food. The nearest store is a 10-minute drive away

Guest favourite
Home in Gamboa
4.86 out of 5 average rating, 109 reviews

BirdHouse@ Gamboa Panama Canal

Explore the wonders of the Panama rainforest and return to our magical tropical home! This unique house and pool is a wonderful place to escape the hustle of Panama City, celebrate nature, and enjoy family and friends. Gamboa is a safe, quiet town embedded in the Soberania National Park; it is the entry point to Pipeline Road, some of the best birding in the world. Or take leave of the forest and watch manatee, while fishing for peacock bass in Gatun Lake or paddling kayaks up the Chagres River.

Superhost
Home in Nuevo Emperador
4.5 out of 5 average rating, 6 reviews

Private property near the city | Exclusive use

Enjoy Finca Los Caobos exclusively, surrounded by nature and just a few minutes from the city Ideal for private family gatherings, intimate celebrations, and special get-togethers, the property features 3 bedrooms, spacious green areas, a pool, and peaceful spaces to relax and share meaningful moments Perfect for guests looking for privacy, comfort, and a relaxed atmosphere Private family gatherings may be considered with prior agreementAny additional activity must be disclosed before booking

Guest favourite
An open-concept loft is showcased with a high, sloped ceiling and large windows that invite natural light. Comfortable seating is arranged around a glass table, while a dining area and a cozy sleeping space can be seen in the background. Nature views are visible through the windows.
Home in Santa Rita Arriba
4.94 out of 5 average rating, 18 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Top guest favourite
Place to stay in Panamá
5 out of 5 average rating, 14 reviews

Casa Condal - Your Luxury Retreat in Cerro Azul

Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Guest favourite
The exterior of the apartment is surrounded by lush tropical greenery, featuring various plants and trees. A balcony is visible on the upper level, providing a vantage point to enjoy the natural setting. Soft sunlight filters through the leaves, creating a serene atmosphere.
Guest house in Gamboa
4.94 out of 5 average rating, 89 reviews

Gamboa - Ñeque Studio, house # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Guest favourite
Cabin in Altos del Maria
4.96 out of 5 average rating, 27 reviews

Fobos – Luxury 1-Bed Cabin with Heated Pool

Relax and enjoy Altos del María and its amenities in our brand-new tiny house. With beautiful views, a private jacuzzi, and a modern design, it truly ticks all the boxes. The house is ideal for couples (2 guests) but children are welcome (maximum 2). The kitchen is fully equipped, the bathroom features a modern design, and the bedroom is cozy and comfortable. Located on a shared lot with two others houses, this tiny house is perfect for enjoying a weekend getaway or a longer stay.

Top guest favourite
Flat in San Felipe
4.98 out of 5 average rating, 121 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Guest favourite
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del Maria
4.82 out of 5 average rating, 323 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

Guest favourite
Cabin in Panamá
4.93 out of 5 average rating, 89 reviews

The Crystal House: Luxury Modern Wood Cabin

Crea recuerdos inolvidables en este alojamiento único e ideal para familias. Quédate en una cabaña en medio del Parque Nacional Chagres a 50 minutos de la ciudad. Podrás estar en contacto con la naturaleza contando con todas las comodidades de un alojamiento de lujo. Con una de las mejores vistas a la ciudad puedes disfrutar de una buena barbacoa, una siesta en la hamaca o una reunión alrededor de la chimenea. Relájate y conéctate con el lindo verde de Panamá. Te esperamos!

Superhost
Home in San Carlos
4.89 out of 5 average rating, 166 reviews

El Palmar, beach 50 meters away

Listen to the waves from the privacy of our terrace and create unforgettable memories in this unique and family-friendly accommodation just steps from the beach with a private pool. El Palmar is a quiet community with several restaurants available a few steps from the house. The property is fully fenced for the tranquility and safety of children and their pets. In addition, you have wifi, cable TV in both rooms and air conditioning in the dining room and in all the bedrooms

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 219 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Popular amenities for Santa Clara holiday rentals

  1. Airbnb
  2. Panama
  3. Distrito Arraijan
  4. Santa Clara