
Holiday rentals in Santa Clara
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Top-rated holiday rentals in Santa Clara
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Spacious Casita with Bamboo View
Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Private property near the city | Exclusive use
Enjoy Finca Los Caobos exclusively, surrounded by nature and just a few minutes from the city Ideal for private family gatherings, intimate celebrations, and special get-togethers, the property features 3 bedrooms, spacious green areas, a pool, and peaceful spaces to relax and share meaningful moments Perfect for guests looking for privacy, comfort, and a relaxed atmosphere Private family gatherings may be considered with prior agreementAny additional activity must be disclosed before booking

Casa Condal - Your Luxury Retreat in Cerro Azul
Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

The Bird's Nest in the Clouds
Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

The Hidden Gem
Here you will find your home away from home in this hidden gem. Furnished with all of the creature comforts, you will have plenty to do from relaxing on the patio while listening to music, to taking a dip in the heated pool, to relaxing on the comfy couch and watching Netflix. The house is situated on a beautiful gated beach property where you can find various activities from kayaking to the local water park. You can find the relaxation you were searching for here in this hidden gem.

Modern House with Great Views and Heated Pool
Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

GreatCanal-Front Luxury 3BR | City & Golf View 401
Welcome to Palash Tower — a rare canal-front gem! Experience luxury in this spacious 3-bedroom, 3-bath apartment set on a 74-hectare gated golf estate. Enjoy panoramic skyline and canal views where ships pass through the lock below. Relax at the rooftop infinity pool, gym, spa, and on-site restaurants. Free parking and 24/7 security included. The only place where the city meets the water and golf in perfect harmony. Minutes from the City Center and Historic Casco Viejo.

Villa Acuario
Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.

The Crystal House: Luxury Modern Wood Cabin
Create unforgettable memories at this unique and family-friendly place. Stay in a cabin in the middle of Chagres National Park, 50 minutes from the city. You can be in contact with nature while having all the comforts of a luxury accommodation. With one of the best views of the city, you can enjoy a good barbecue, a nap in the hammock, or a meeting around the fireplace. Relax and connect with the beautiful green of Panama. We'll be waiting for you!

Tropical Haven with Pickleball/Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Cerro Azul Mountain Retreat a magical home.
Enjoy every corner and luxury in this spacious house with 6 rooms with airs and 6 bathrooms. The perfect terrace to relax outdoors, while the ideal dining room to share special moments with your loved ones. The greenhouse is an oasis of fresh ingredients, ready to inspire delights. We have a new deck and jacuzzi ready to enjoy allowing you to connect with nature and beautiful sunsets. It has a game room, soccer pool table and a/ac
Popular amenities for Santa Clara holiday rentals
Other great holiday rentals in Santa Clara

Chagres River Lodge

Gamboa - Ñeque Studio, house # 126

Canal Loft

La Florecita - Country house in Valle de Antón

Luxury beachfront villa!

Most Beautiful Loft in the Heart of Casco Viejo

House in Costa Verde, West Panama

Flor del Aire Cabin
Destinations to explore
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