Skip to content

Holiday rentals in Saint Charles

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Saint Charles

Guests agree: these stays are highly rated for location, cleanliness, and more.

Rental unit in Saint Charles
Ella Rose Guest Suite in Historic Old St Charles
Welcome to The Ella Rose Guest Suite! This adorable gem represents everything you love about Old St. Charles. This cozy suite just steps away from the heart of Main Street, restaurants, and all the action St. Charles has to offer. The Ella Rose is a charming one-bedroom, with an open and airy living room and kitchen. It has natural light and high ceilings throughout. It's farmhouse cottage decor makes for a relaxing place to rest. Come sit and listen to music of our outdoor bubbler rock.
Professional Host
SUPERHOST
Home in Saint Charles
Bright & Cozy Shotgun 1 Block from Historic DT.
Admire this unique historic home's design with brand new amenities and antique details that give a fresh and charming feel. Built in the 1930's, this half of the duplex has a typical shotgun layout with ten-foot ceilings giving a spacious feel. The front door leads directly to the living room, then into the bedroom, both of which have the original hard wood floors. The back of the house has the kitchen, with exposed brick, a dining area, and a bathroom with a washer and dryer.
SUPERHOST
Rental unit in Saint Charles
South Main Comfort
Check out this very stylish 1 bedroom apartment on South Main. All of the amenities have been checked off the list from a dedicated office space and good sized living room, to an outdoor (shared) dinning area, historic styling in modern comforts. King bed, laundry in unit, dishwasher, and free 24/7 gym access down the street along with off street parking. We've thought of it all to help you be more comfortable for your stay in St. Charles!
Individual Host
SUPERHOST

Stay near Saint Charles's top sights

Photo of Ameristar Casino Resort Spa St. Charles
Ameristar Casino Resort Spa St. Charles42 locals recommend
Photo of Hollywood Casino St. Louis
Hollywood Casino St. Louis20 locals recommend
Photo of The Family Arena
The Family Arena12 locals recommend
Photo of St. Charles Convention Center
St. Charles Convention Center6 locals recommend
Photo of Tucanos Brazilian Grill
Tucanos Brazilian Grill8 locals recommend
Photo of Bar Louie - Streets of St. Charles
Bar Louie - Streets of St. Charles21 locals recommend

Other great holiday rentals in Saint Charles

Private room in St. Louis
♥Clean & fresh & cozy -- 5 min from airport!
Individual Host
SUPERHOST
Rental unit in Saint Charles
2 Bedroom, 1 Bath Walking Distance to Main Street
Individual Host
SUPERHOST
Rental unit in Saint Charles
The Bricks On Main-King Bed on Historic Main St.
SUPERHOST
Rental unit in Saint Charles
Main Street Living! 2 Bedroom Unit right On Main!
Individual Host
SUPERHOST
Rental unit in Saint Charles
Pop Lucks Guest Suite Steps From Historic Main St
Professional Host
SUPERHOST
Private room in Saint Charles
JT's retreat
Rental unit in Saint Charles
Quiet 1 bedroom apartment near Main Street!
Individual Host
SUPERHOST
Bungalow in Saint Charles
Patio House, secluded in heartbeat of Main Street
Professional Host
SUPERHOST
Rental unit in Saint Charles
Best Views on South Main
Individual Host
SUPERHOST
Rental unit in Saint Charles
Quaint, comfy boutique apt, Pets are welcome
Townhouse in Saint Charles
Spacious Historic Townhouse in Frenchtown
SUPERHOST
Rental unit in Saint Charles
Stay on Main!
Individual Host
SUPERHOST

Stays in Saint Charles

Home in Saint Charles
Historic 2 bedroom house St Charles
Individual Host
SUPERHOST
Rental unit in Saint Charles
Stylish One Bedroom Apartment close to Main!
Individual Host
SUPERHOST
Private room in St. Louis
★Cozy, so fresh, so clean -- 5 min from airport!!
Individual Host
SUPERHOST
Rental unit in Saint Charles
Overlook Main St. in this 2 bedroom owners suite!
Individual Host
SUPERHOST

Stays in Earth City

Rental unit in Saint Charles
Cobblestone Suite - 1 Bed/1 Bath Main Street
Individual Host
SUPERHOST
Private room in Saint Charles
Delightful room close to the St. Louis airport.
Individual Host
SUPERHOST
Private room in Florissant
Cozy Getaway. Close to Airport and 4 major highway
Individual Host
SUPERHOST
Private room in St. Louis
Kathie's Casa
Individual Host
SUPERHOST

Other types of stays on Airbnb