Holiday rentals in Panama City

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness and more.

0 of 0 items showing

1 of 3 pages

Guest favourite

Apartment in Panama

4.99 out of 5 average rating, 205 reviews

Patty’s Cozy & Quiet Studio with K-bed in Casco

*TOTALLY renovated on NOV 15th 2023: new floors, modern bathroom, new design & art work* Photos to come! Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen beside from the main living space. It is spacious, comfortable and tastefully decorated!

4–11 Oct

€ 99 per night

Guest favourite

Flat in Panamá

4.96 out of 5 average rating, 28 reviews

Stunning Sea View apt at city center

Enjoy a stylish experience with a stunning see view where you can see the ship crossing the Canal of Panamá and be in the city central at the same time. This spacious place has 1 big bed room with walking closet and 1.5 bathroom. Fully equipment kitchen and laundry room. All furnitures have been renewed. Reliable 400 MB internet speed. Roof top social area. This lovely place is well connected, 2 min to Cinta Costera, 7 min to Multiplaza, 8 min to Casco Antiguo and 35 min to Tocumen Airport.

10–17 Jan

€ 102 per night

Guest favourite

Flat in Panamá

5.0 out of 5 average rating, 27 reviews

Amazing experience in Casco Viejo with ocean views

Disfruta la cultura panameña desde el centro de Casco Viejo, donde conocerás la arquitectura colonial, podrás visitar los mejores restaurantes, sitios nocturnos y rooftops característicos de la zona. Apartamento tranquilo y confortable. Cuenta con una cama queen, 1.5 baños, armario, aire acondicionado, cocina equipada, comedor, sala, acceso a WiFi de 500 mbps, espacio de trabajo, balcón y comedor al aire libre. ¡Te ofrecemos todo lo que necesitas para vivir la mejor experiencia local!

2–9 Jul

€ 109 per night

Guest favourite

Flat in Panama City

5.0 out of 5 average rating, 20 reviews

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

20–27 Oct

€ 136 per night

Guest favourite

Townhouse in Panamá

4.97 out of 5 average rating, 160 reviews

Casa Casco Amigos - The Only House in Casco.

Located by the French Embassy in Casco Viejo in the absolute safest and most prestigious area of Panama City, Casa Casco Amigos is a 3 level, 3 bedroom 351 square meter house with a roof terrace and a garden terrace which can sleep 9. Despite the liveliness of the area, there is no noise whatsoever in the bedrooms. Perfect for 1 or 2 families, or a group of 6 to 9 friends who want to be in the heart of the old city, with a sea view and many areas to lounge and avoid the midday heat.

23–30 Sep

€ 354 per night

Guest favourite

Flat in Panamá

4.95 out of 5 average rating, 152 reviews

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

7–14 Jul

€ 171 per night

Guest favourite

Flat in Panamá

4.97 out of 5 average rating, 128 reviews

Angie’s Place Cozy n Comfy in the ❤️ of #CascoViejo

Remodelado, cómodo y céntrico en el corazón de Casco Viejo, pintoresco lugar declarado Patrimonio de la Humanidad por la UNESCO. Cerca de restaurantes, Bares, Impresionantes Iglesias y Museos. La propiedad data del siglo XVII (1756) historia y buen ambiente. Podrás explorar la zona a pie, cocina full equipada, te sentirás como en casa, rodeado de las famosas paredes de calicanto. -Amplia sala de estar-Smart tv -Cocina full equipada -1.5 baños Policía de turismo 24/7

27 May – 3 Jun

€ 103 per night

Guest favourite

Loft in Panamá

4.91 out of 5 average rating, 174 reviews

Amazing Loft with the Best view of Casco viejo!

Hermoso loft ubicado en el centro de Casco Antiguo, la zona más turística de Panamá. Ven, disfruta y relájate en este impresionante loft, con una vista increíble de la Catedral de Panamá. Puedes visitar museos, bares, restaurantes e iglesias ubicados a tan solo unos cuantos metros de distancia. Beatiful Loft located in the center of Casco Antiguo, Panama´s most turistic location. Come, enjoy and relax at this amazing loft, with amazing view to Panama´s Cathedral.

5–12 Mar

€ 110 per night

Guest favourite

Flat in Panamá

4.87 out of 5 average rating, 31 reviews

Beautiful apartment in Casco Viejo

Located in the heart of Casco Viejo. It has a button service that takes your luggage to the apartment, it has a rooftop where you can watch the sunset with the view of the city, the canal and the majestic sea. The building's ground floor is home to La Cuadra Market where there are a variety of renowned restaurants with different styles of food, as well as a bar. Close to everything, you can walk around everything and enjoy every place it offers you.

23–30 Nov

€ 79 per night

Guest favourite

Flat in Panama City

4.97 out of 5 average rating, 38 reviews

Stunning views from the clouds!

*** Internet 500Mbps Wifi Pro *** *** Netflix, Prime Video, HBOmax, Youtube Premium *** Cozy and spectacular apartment all dressed in white. You will enjoy daily incredible views of the symbols of Panama: the islands, Causeway, Old Town, Canal, Metropolitan park. In this bubble over the bay, you will feel like in the clouds! Place of inspiration and relaxation, strategically located, you will have the whole city at your feet!

12–19 Sep

€ 174 per night

Guest favourite

Flat in Panamá

5.0 out of 5 average rating, 19 reviews

Luxury Apartment Panama Centro, Banking Area

We have a strategic location right on Panama's main thoroughfare (Calle 50) Bella Vista, you are located in the heart of the banking area. If you are coming for work or vacation, this is the ideal place, you will find all kinds of restaurants nearby, shops, shopping center, you will have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

30 Oct – 6 Nov

€ 55 per night

Guest favourite

Flat in Panamá

5.0 out of 5 average rating, 36 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a central place where you will find ample gastronomy, fun places, close to bus stations, and the most important shopping center in the city, Multiplaza. This central and quiet apartment is an opportunity that you will not want to let in. Offer the perfect combination of comfort, beauty, and convenient location.

29 Mar – 5 Apr

€ 78 per night