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Vacation rentals in Rochester

Vacation rentals in Rochester

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Rochester

Guests agree: these stays are highly rated for location, cleanliness, and more.

  • Home Away From Home-10 minute drive to Mayo Clinic
    SUPERHOSTEntire flat · 2 guests · 1 bed · 1 bathroom
    Home Away From Home-10 minute drive to Mayo Clinic

    This great space has a private, self-entrance with off-street parking...a mere 3.2 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. It boasts easy access to highways, convenience to grocery store, coffee shop, Target, restaurants and the biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with coffee. It is your home away from home!

    What guests are saying:

    “I spent a month at Berni's airbnb and had a wonderful experience. The space itself is cozy, inviting and nicely decorated. It is very well equipped for a long term stay- it has every kind of kitchen accessory you could need and use of washer/dryer. The host (Berni) is wonderful!! She brought baked goods for us multiple times, let me borrow tools when I needed to fix my bike (even helped me to fix it!), and checked in via text to make sure we had everything we needed. If I did have a question, she responded very quickly to text. She is very kind and great to talk with as well. I would absolutely stay here again in the future!”

  • Magical Nest
    SUPERHOSTPrivate room · 2 guests · 1 bed · 1 shared bathroom
    Magical Nest

    A one room studio apartment located in a very nice, quiet neighborhood. We are located just a mile from the Mayo Clinic. Most restaurants and places you'd like to visit are only a 10-12 minute drive away!

    What guests are saying:

    “We stayed here for a second time. The apartment is beautifully decorated, very clean, extra touches throughout quiet neighborhood, and beautiful surroundings. The host went out of his way to make sure our needs were met, and made us feel welcome. Just as good (in some cases, better) than the upper end hotels we've stayed at!”

  • Modern and fresh space very close to Mayo Clinic
    SUPERHOSTEntire house · 2 guests · 0 beds · 1 bathroom
    Modern and fresh space very close to Mayo Clinic

    Completely updated duplex! I put all my time, energy, and money to make this property perfect for my guests. I am a lifelong carpenter so I take pride in my work. I have painted every surface.(walls and ceilings) New appliances, sinks, curtains, trim, lighting and cabinets. There are many restaurants within blocks and a Walgreens a block away. I have put everything into making this space perfect for my guests so I expect all guests to respect it.

    What guests are saying:

    “Tom's place was very clean and comfortable. I was extremely impressed. The house layout was perfect for 1-2 people, with multiple areas to relax. I love the Roku TV & the Keurig coffee dispenser. The little touches such as the guest book with info about local restaurants that Tom & Lindsey prefer, the house rules reminder and WiFi details was very helpful. The location was perfect; so close to everything I had to go to, in fact, I had a great walk to St. Mary's one morning. This was everything I could have asked for.”

Holiday rentals for every style

Get the amount of space that is right for you.

  • Homes
  • Hotels
  • Unique stays

Popular amenities for Rochester holiday rentals

  • Kitchen
  • Wifi
  • Pool
  • Free parking on premises
  • Air conditioning

Other great holiday rentals in Rochester

Cozy, comfy 1 BR unit in triplex, 4 blocks to Mayo
SUPERHOSTEntire flat
Cozy, comfy 1 BR unit in triplex, 4 blocks to Mayo
Price:€41 / night
Home Away From Home-10 minute drive to Mayo Clinic
SUPERHOSTEntire flat
Home Away From Home-10 minute drive to Mayo Clinic
Price:€42 / night
Private cozy apartment *NEAR MAYO* Remodeled!
SUPERHOSTEntire flat
Private cozy apartment *NEAR MAYO* Remodeled!
Price:€49 / night
The Little House
SUPERHOSTEntire house
The Little House
Price:€50 / night
Modern and fresh space very close to Mayo Clinic
SUPERHOSTEntire house
Modern and fresh space very close to Mayo Clinic
Price:€53 / night
Magical Nest
SUPERHOSTPrivate room
Magical Nest
Price:€36 / night
At Home in Minnesota
SUPERHOSTPrivate room
At Home in Minnesota
Price:€27 / night
Charming and stylish home- 4 blocks from Mayo :)
SUPERHOSTEntire house
Charming and stylish home- 4 blocks from Mayo :)
Price:€72 / night
Cozy 1 Bd, 1 Bth 4 blocks from Mayo
Entire flat
Cozy 1 Bd, 1 Bth 4 blocks from Mayo
Price:€41 / night
5 blocks from Mayo, Adorable Upper Unit
SUPERHOSTEntire house
5 blocks from Mayo, Adorable Upper Unit
Price:€49 / night
Your Mayo/Roch Home 
(KING bed, 1 mile from Mayo)
SUPERHOSTPrivate room
Your Mayo/Roch Home (KING bed, 1 mile from Mayo)
Price:€27 / night
Cozy Studio near Mayo Clinic & Downtown Rochester
SUPERHOSTEntire apartment
Cozy Studio near Mayo Clinic & Downtown Rochester
Price:€49 / night
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