
Holiday rentals in Panamá Province
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Panamá Province
Guests agree: these stays are highly rated for location, cleanliness and more.

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Spectacular duplex penthouse in Panama City’s historic centre, 265 m² with balconies and private outdoor terraces. It features an indoor garden lounge, a dining room, and 3 bedrooms (plus a sofa bed in the studio). Recently renovated in a loft style, it offers a unique, exclusive and comfortable design, located in the best part of the historic centre, perfect for relaxing and unwinding. Kitchen, dishwasher, living room with washing machine, shared swimming pool, lift, 24/7 doorman. Children who cannot swim are not allowed. Wide range of leisure activities in the area.

In the heart of Casco, refurbished and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Estilo colonial con calicanto y balcón privado
Bienvenidos a un apartamento acogedor donde el encanto de las paredes de calicanto se mezcla con detalles cálidos y un balcón perfecto para disfrutar del ambiente y la vista del Casco Antiguo. Tenemos una ubicación privilegiada en una de las principales avenidas del Casco, desde aquí podrás acceder fácilmente a sitios históricos, restaurantes, cafés, bares y rincones llenos de encanto. La idea es que llegues, te sientas cómodo, disfrutes la ciudad a tu ritmo, ya sea solo, en pareja o en familia.

Casa Condal - Your Luxury Retreat in Cerro Azul
Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Peaceful Stay in the Heart of Casco
Enjoy a quiet and comfortable apartment in the center of Casco Viejo. It’s a great place to relax after walking around the neighborhood, with everything you need for a nice stay. Restaurants, cafés, and main attractions are just a short walk away. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Modern apt ocean view in heart of Panamá yoo tower
Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Patty’s Casco 2BR Loft | Balcony & Personal Touch
“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Cerro Azul Mountain Retreat a magical home.
Enjoy every corner and luxury in this spacious house with 6 rooms with airs and 6 bathrooms. The perfect terrace to relax outdoors, while the ideal dining room to share special moments with your loved ones. The greenhouse is an oasis of fresh ingredients, ready to inspire delights. We have a new deck and jacuzzi ready to enjoy allowing you to connect with nature and beautiful sunsets. It has a game room, soccer pool table and a/ac

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
Popular amenities for Panamá Province holiday rentals
Other great holiday rentals in Panamá Province

Most Beautiful Loft in the Heart of Casco Viejo

The Hidden Gem

Luxury apt in Panama City 2 Rooms 3 Baths

Luxury Apartment | Walk to Restaurants & Shops

Walk to Everything | Luxury Stay in Casco Viej

The Crystal House: Luxury Modern Wood Cabin

Panoramic Casco Viejo Lookout in The Sands

A warm and cozy flat in Casco Viejo
Destinations to explore
- Apartment rentals Panamá Province
- Pet-friendly rentals Panamá Province
- Rentals with a kayak Panamá Province
- Townhouse rentals Panamá Province
- Rentals with a sauna Panamá Province
- Hostel rentals Panamá Province
- Serviced apartment rentals Panamá Province
- Rentals with beach access Panamá Province
- Guest house rentals Panamá Province
- Boat rentals Panamá Province
- Flat rentals Panamá Province
- Rentals with an accessible-height bed Panamá Province
- Tiny house rentals Panamá Province
- Private suite rentals Panamá Province
- Family-friendly rentals Panamá Province
- Waterfront rentals Panamá Province
- Beachfront rentals Panamá Province
- Rentals with breakfast Panamá Province
- Villa rentals Panamá Province
- Bed and breakfasts Panamá Province
- Holiday home rentals Panamá Province
- Rentals with a hot tub Panamá Province
- Nature eco lodge rentals Panamá Province
- Boutique hotels Panamá Province
- Loft rentals Panamá Province
- Rentals with pools Panamá Province
- Rentals with lake access Panamá Province
- Hotel rooms Panamá Province
- House rentals Panamá Province
- Cabin rentals Panamá Province
- Things to do Panamá Province
- Nature and outdoors Panamá Province
- Sports activities Panamá Province
- Food and drink Panamá Province
- Tours Panamá Province
- Sightseeing Panamá Province
- Art and culture Panamá Province
- Things to do Panama
- Nature and outdoors Panama
- Sports activities Panama
- Sightseeing Panama
- Tours Panama
- Art and culture Panama
- Food and drink Panama





