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Holiday rentals in Panama Canal

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Top-rated holiday rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness and more.

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An indoor garden is showcased, featuring lush greenery and soft lighting. A glass roof allows natural light to illuminate the space, which is accented by warm-toned stone walls. Two stylish chairs are positioned nearby, creating a comfortable seating area.
Apartment in San Felipe
4.88 out of 5 average rating, 150 reviews

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES

Spectacular duplex penthouse in Panama City’s historic centre, 265 m² with balconies and private outdoor terraces. It features an indoor garden lounge, a dining room, and 3 bedrooms (plus a sofa bed in the studio). Recently renovated in a loft style, it offers a unique, exclusive and comfortable design, located in the best part of the historic centre, perfect for relaxing and unwinding. Kitchen, dishwasher, living room with washing machine, shared swimming pool, lift, 24/7 doorman. Children who cannot swim are not allowed. Wide range of leisure activities in the area.

Guest favourite
Flat in San Felipe
4.96 out of 5 average rating, 260 reviews

In the heart of Casco, refurbished and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Top guest favourite
Place to stay in Panama City
5.0 out of 5 average rating, 26 reviews

Casa Condal - Your Luxury Retreat in Cerro Azul

Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Guest favourite
Flat in Panama City
4.95 out of 5 average rating, 77 reviews

VIP Suite/Sea View + Pool & Sky Lounge + Gym

Elegant studio suite with stunning ocean views, located on Panama city iconic Cinta Costera. Ideal for business travelers, couples, or tourists seeking style, comfort, and convenience. Features a full kitchen, spacious bathroom, fast Wi-Fi, and washer/dryer. Enjoy top amenities: pool, gym, sky lounge, game room, restaurants, and 24/7 security. Hosted with care by César & Claudia to ensure a warm and memorable stay in Panama . Remember to check our Guide. With parking include !

Top guest favourite
Flat in San Felipe
4.98 out of 5 average rating, 130 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Top guest favourite
Flat in San Felipe
4.98 out of 5 average rating, 40 reviews

Walk to Everything | Luxury Stay in Casco Viej

Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Guest favourite
A spacious living area features light wood flooring and a modern open kitchen. Two light-colored sofas surround a marble coffee table, while a dining area with a stylish table sits nearby. A spiral staircase leads to the upper level, and decorative artwork adorns the walls.
Loft in San Felipe
4.93 out of 5 average rating, 124 reviews

Loft 3b Old Town Best! It's 150 m2 (492 feet)

Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Top guest favourite
Flat in San Felipe
5.0 out of 5 average rating, 33 reviews

Most Beautiful Loft in the Heart of Casco Viejo

Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Guest favourite
Flat in San Felipe
4.92 out of 5 average rating, 65 reviews

Casa del Horno | A Piece of Panamanian History

Enjoy a different experience in the center of the Old Town. Casa del Horno is a historic building created from the restoration of an old mid-19th century structure, which retains the character of its calicanto walls. Today, this space combines history, comfort and a very prime location. You will be surrounded by restaurants, cafes, and bars, and you will have very easy access to Panama's most iconic sites.

Guest favourite
Home in Gamboa
4.86 out of 5 average rating, 111 reviews

BirdHouse — Gamboa, Panama Canal Rainforest

BirdHouse: Let's inhabit the space. Designed for people who want to experience the tropics, not shut them out. Open the screens, feel the breeze, listen to the rain, cool off in the pool, and wake to birds and howler monkeys. Located in historic Gamboa, BirdHouse is a place to slow down and experience one of the world’s richest tropical forests from the comfort of a thoughtfully designed home.

Top guest favourite
A dining table is set with elegant glassware and plates, positioned by a balcony that overlooks lush green foliage. The scene captures the natural light filtering through nearby plants, providing a nice view of the tranquil outdoor setting.
Apartment in San Felipe
4.99 out of 5 average rating, 293 reviews

Patty’s Charming Serene Studio in Casco Viejo

Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen aside from the main living space. It is spacious, comfortable and tastefully decorated!

Guest favourite
An interior view showcases a modern, multi-level loft with a wooden staircase leading to the upper loft area. Soft lighting creates ambient hues throughout the open space, highlighting the kitchen and living areas, where stylish furniture is arranged for comfort. Exposed stone walls add texture.
Loft in Panama City
4.89 out of 5 average rating, 356 reviews

2B Loft Studio | Design By Paradox

PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.

Popular amenities for Panama Canal holiday rentals