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Holiday rentals in Panama Canal

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Flat in San Felipe
4.96 out of 5 average rating, 260 reviews

In the heart of Casco, refurbished and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Guest favourite
Flat in Panama City
4.95 out of 5 average rating, 77 reviews

VIP Suite/Sea View + Pool & Sky Lounge + Gym

Elegant studio suite with stunning ocean views, located on Panama city iconic Cinta Costera. Ideal for business travelers, couples, or tourists seeking style, comfort, and convenience. Features a full kitchen, spacious bathroom, fast Wi-Fi, and washer/dryer. Enjoy top amenities: pool, gym, sky lounge, game room, restaurants, and 24/7 security. Hosted with care by César & Claudia to ensure a warm and memorable stay in Panama . Remember to check our Guide. With parking include !

Guest favourite
A modern living area is featured, showcasing a large wall-mounted television surrounded by a lighted panel. Seating is provided by a dark sofa with decorative pillows. A round dining table is visible in the foreground, complemented by four black chairs. Tall windows offer city views.
Flat in Panama City
4.86 out of 5 average rating, 71 reviews

Luxury Oceanfront Resort 22nd Floor View, 200°

Luxury oceanfront apartment on the 22nd floor with breathtaking panoramic views of Panama Bay, the skyline, and historic Casco Antiguo. Located on the famous Cinta Costera, this resort-style apartment offers 2 bedrooms, 2 bathrooms, luxury kitchen, 65” TVs, washer/dryer, and sleeps up to 6 guests. Enjoy spectacular sunsets from the balcony and access to infinity pool, gym, and premium amenities, just minutes from restaurants, nightlife, and Panama City’s top attractions.

Superhost
A modern living area features a large wave mural that enhances the space's vibrant decor. Comfortable seating arrangements include a sleek white sofa and a pair of stylish armchairs. A glass coffee table is centered among the furnishings, with tastefully arranged decorative accents.
Flat in Bella Vista
4.91 out of 5 average rating, 329 reviews

Modern apt ocean view in heart of Panamá yoo tower

This special place is close to everything, making it easy to plan your visit. Ph Yoo and Arts, located on Av. Balboa, very central This beautiful and modern property has a unique style and an incredible ocean view, high floor, 2 bedrooms, 2.5 full bathrooms, laundry, large terrace, dimmable lights throughout the space, dining room, movie room, workspace, 3 smart TVs, 3 central air conditioners, fully equipped kitchen, modern glassware.

Guest favourite
A spacious living area features light wood flooring and a modern open kitchen. Two light-colored sofas surround a marble coffee table, while a dining area with a stylish table sits nearby. A spiral staircase leads to the upper level, and decorative artwork adorns the walls.
Loft in San Felipe
4.93 out of 5 average rating, 124 reviews

Loft 3b Old Town Best! It's 150 m2 (492 feet)

Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Top guest favourite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Flat in Bella Vista
4.92 out of 5 average rating, 174 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favourite
A modern living area features a white sectional sofa adorned with colorful cushions. A sleek coffee table sits in front of a mounted television. Large windows provide expansive views of the city skyline, enhancing the bright and airy feel of the space.
Flat in Bella Vista
4.89 out of 5 average rating, 194 reviews

Beautiful Apt, Best Location 2BR

Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.

Superhost
Flat in San Felipe
4.92 out of 5 average rating, 66 reviews

Casa del Horno | A Piece of Panamanian History

Enjoy a different experience in the center of the Old Town. Casa del Horno is a historic building created from the restoration of an old mid-19th century structure, which retains the character of its calicanto walls. Today, this space combines history, comfort and a very prime location. You will be surrounded by restaurants, cafes, and bars, and you will have very easy access to Panama's most iconic sites.

Guest favourite
Home in Gamboa
4.86 out of 5 average rating, 111 reviews

BirdHouse — Gamboa, Panama Canal Rainforest

BirdHouse: Let's inhabit the space. Designed for people who want to experience the tropics, not shut them out. Open the screens, feel the breeze, listen to the rain, cool off in the pool, and wake to birds and howler monkeys. Located in historic Gamboa, BirdHouse is a place to slow down and experience one of the world’s richest tropical forests from the comfort of a thoughtfully designed home.

Guest favourite
Flat in Panama City
4.89 out of 5 average rating, 142 reviews

Modern, central and comfortable (001)

Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!

Guest favourite
An interior view showcases a modern, multi-level loft with a wooden staircase leading to the upper loft area. Soft lighting creates ambient hues throughout the open space, highlighting the kitchen and living areas, where stylish furniture is arranged for comfort. Exposed stone walls add texture.
Loft in Panama City
4.89 out of 5 average rating, 356 reviews

2B Loft Studio | Design By Paradox

PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.

Guest favourite
Flat in Panama City
4.92 out of 5 average rating, 71 reviews

Old Town & Ocean View

Stunning views of the ocean and the Old Town, with direct access to the Poin Panamá resort, as well as a variety of dining options and bars, for an unparalleled vacation experience. ⚠️ Important notice: The building's pool and gym will be temporarily closed for maintenance from August 24 to September 15, 2026. Thank you for your understanding.

Popular amenities for Panama Canal holiday rentals