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Holiday rentals in Panama Bay

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Top-rated holiday rentals in Panama Bay

Guests agree: these stays are highly rated for location, cleanliness and more.

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Superhost
An indoor garden is showcased, featuring lush greenery and soft lighting. A glass roof allows natural light to illuminate the space, which is accented by warm-toned stone walls. Two stylish chairs are positioned nearby, creating a comfortable seating area.
Apartment in Panamá
4.88 out of 5 average rating, 143 reviews

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES

Spectacular duplex penthouse in Panama City’s historic centre, 265 m² with balconies and private outdoor terraces. It features an indoor garden lounge, a dining room, and 3 bedrooms (plus a sofa bed in the studio). Recently renovated in a loft style, it offers a unique, exclusive and comfortable design, located in the best part of the historic centre, perfect for relaxing and unwinding. Kitchen, dishwasher, living room with washing machine, shared swimming pool, lift, 24/7 doorman. Children who cannot swim are not allowed. Wide range of leisure activities in the area.

Top guest favourite
Flat in Panamá
4.94 out of 5 average rating, 145 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Top guest favourite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Flat in Panama City
5 out of 5 average rating, 73 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Top guest favourite
Flat in Panama City
4.97 out of 5 average rating, 116 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, you will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. This restored- colonial building was built in the year 1850, and features some of the original "calicanto" walls. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Guest favourite
A modern living area features a large wave mural that enhances the space's vibrant decor. Comfortable seating arrangements include a sleek white sofa and a pair of stylish armchairs. A glass coffee table is centered among the furnishings, with tastefully arranged decorative accents.
Flat in Panamá
4.93 out of 5 average rating, 312 reviews

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Top guest favourite
Loft in Panama
4.99 out of 5 average rating, 174 reviews

Patty’s Casco 2BR Loft | Balcony & Personal Touch

“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 217 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Top guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in Panamá
4.98 out of 5 average rating, 187 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favourite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Flat in Panama City
4.92 out of 5 average rating, 115 reviews

The best view of the Old Town

¡Bienvenidos a este encantador alojamiento situado en el corazón del Casco Viejo, ubicado en el tercer piso frente a una de las plazas más emblemáticas de Panamá, la Plaza Catedral! Gracias a su privilegiada ubicación, disfrutarás de una vista única a la plaza y a la imponente Iglesia Catedral. Justo en esta animada plaza, tendrás a tu disposición una amplia variedad de restaurantes y tiendas donde podrás adquirir recuerdos de este maravilloso viaje.

Superhost
The exterior of the duplex is surrounded by lush greenery, featuring palm trees and tropical plants. A hammock is visible suspended between two trees, creating a serene outdoor relaxation area. The structure has a classic white façade, with a deck partially obscured by foliage.
Guest suite in Gamboa
4.93 out of 5 average rating, 107 reviews

Beautiful annex in canal house steps from Canal.

Enjoy nature in this historic town from 1931, located in Soberanía Park along the Panama Canal. Just 40 minutes from the bustling capital, you can relax while strolling, exploring colonial ruins, birdwatching in Pipeline, or fishing in the Chagres River. Visit Monkey Island, explore an indigenous village, and observe sloths. Perfect for mountain biking enthusiasts. As night falls, take a relaxing bath and sleep peacefully in this natural retreat.

Top guest favourite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Las Colinas de Caceres de Arraijan
4.98 out of 5 average rating, 230 reviews

Tropical Haven with Pickleball/Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Guest favourite
A spacious living area features light wood flooring and a modern open kitchen. Two light-colored sofas surround a marble coffee table, while a dining area with a stylish table sits nearby. A spiral staircase leads to the upper level, and decorative artwork adorns the walls.
Loft in Panamá
4.93 out of 5 average rating, 120 reviews

Loft 3b Old Town Best! It's 150 m2 (492 feet)

Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Popular amenities for Panama Bay holiday rentals

  1. Airbnb
  2. Panama
  3. Panama Bay