
Pet-friendly holiday rentals in Orangeburg County
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Top-rated pet-friendly home rentals in Orangeburg County
Guests agree: these pet-friendly homes are highly rated for location, cleanliness and more.

Cozy, comfy, convenient, cottage!
We think you'll love this peaceful, family friendly cottage. For a price similar to a local hotel, you'll get a newly remodeled 2-bedroom house complete with kitchen and formal dining room located on fenced in lot 🐶 in quiet neighborhood. The master has a king bed with 400 count Egyptian cotton sheets and a bamboo mattress topper. The guest has a queen bed with a sensafoam mattress. There is a new 50” tv and high speed fiber WI-FI. There is also a breakfast bar with your favorite coffee.

Mulberry Cabin, a rustic tiny house cabin
Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Log home on Lake Marion inlet w/private dock.
Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Lake Life Living-W/Boat waterfront condo
Nestled in a cozy cove along the shores of Lake Marion, this pet friendly retreat offers an escape for anglers, boaters, and golfers seeking both tranquility and convenience. This 2-bed, 2-bath condo is conveniently located off I95, making it an excellent base for exploring nearby areas. Lake Marion ranks among the largest lakes in the US offering world-class fishing. Santee also provides an exceptional golfing challenge making this a premier vacation destination for the golf enthusiasts.

Luxury Farm Stay | Hot Tub, Pool & Animals
Welcome to The Days End Farm! Where modern comfort meets country charm 🌾 This home is for quiet stays only — no parties or events are allowed. A thoughtfully designed 700 sq ft farm cabin retreat tucked away on 11 acres of peaceful pastures. Located less than 45 min from downtown Summerville, 40 min from I-20, 1 hr from Downtown Charleston, and 25 min from I-95. We are a livestock property and for the safety of our animals we only allow 1 pet per reservation with a strict leash policy.

Relaxing Comfortable Waterfront Family Dock Suite
Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Luxurious Lakefront Log Home W/Pool & hot tub
Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Country Resting Spot
This cozy 2-bedroom, 2-bathroom single-wide manufactured home offers a peaceful retreat in a serene rural setting. Situated on a spacious lot with a large yard, this property provides ample outdoor space for relaxation and play. Conveniently located near Lake Marion. Lcoated off I95 - west about 12 mins (striaght shot). Just west of Elloree SC about 2-3 miles. Perfect layover for that long drive. no smoking inside or vaping inside We love your pets! $12 per pet per night.

Pet-Friendly Lake Marion Getaway - Just off I-95!
In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Tiny Pond House
Reconnect with nature at this unforgettable escape. The best part of our pond cabin is the view! The outdoor space can be utilized to take in fresh air and escape the busyness of life and far outweighs the tiny square footage. Escape, relax and enjoy your home away from home. Our home is meant for one to two people to have a cozy, minimalistic experience but comes with all the amenities. All are welcome to use of the pond , so feel free to bring your fishing rods & tackle.

House on Healing Springs Rd
Welcome to your cozy retreat in the heart of Amish country, surrounded by lush greenery and a private backyard! Inside, you’ll find a spacious living room, a fully equipped kitchen, and a comfortable sitting area. The cottage is just a two-minute walk from the famous Healing Springs, where you can relax and restore in nature’s beauty. Right next door, you’ll discover a small Amish store offering their best local sandwiches, baked goods, and other delights.

Furnished 3BR Near MUSC, SC State & Claflin
Relax in comfort at Stamford Haven Retreat! Enjoy a private fenced backyard with patio seating, a zero-gravity massage chair, and a fully stocked kitchen. Wake up to our Keurig coffee bar with coffee, teas, iced tea, creamers, sugar, and honey. Washer/dryer with detergent pods included. Minutes from SCSU, Claflin, MUSC, shopping, and dining—the perfect home away from home with hotel-style comforts and thoughtful amenities for every stay!
Popular amenities for Orangeburg County pet-friendly home rentals
Pet-friendly house rentals

Viridian Retreat

Lakefront home with boat ramp and game room

Lakefront w/ dock at Mill Creek

Fisherman's Dream at Low Falls Landing-Lake Marion

Almost Heaven on Lake Marion, SC

Rest and Relaxation

Large Lakefront Home w/360 view, beaches & dock

Blue Bungalow
Pet-friendly home rentals with a pool

Lakefront Lookout

Lake Marion - Majestic Big Water Views

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

Lakefront Farmhouse Retreat+Pool at Lake Marion

The Azalea Lakehouse

Enjoy Your Day On the Lake! Direct Access w/Dock
Private, pet-friendly home rentals

Charming Octagon Cabin for a Peaceful Escape

Outdoorsman's Paradise

Camping Cabin at Lake Marion in Rimini, SC

Shotgun Cabins-#3-Beretta

Carolina Cottagecore

Nene's Cozy Corner

Dockside Villa Lake Marion

Camper/RV site; 30/110 power, water
Destinations to explore
- Apartment rentals Orangeburg County
- Hotel rooms Orangeburg County
- Flat rentals Orangeburg County
- Rentals with pools Orangeburg County
- Family-friendly rentals Orangeburg County
- Rentals with a kayak Orangeburg County
- Rentals with a hot tub Orangeburg County
- Rentals with lake access Orangeburg County
- House rentals Orangeburg County
- Pet-friendly rentals South Carolina
- Pet-friendly rentals United States
- University of South Carolina
- Congaree National Park
- Riverbanks Zoo and Garden
- Williams Brice Stadium
- South Carolina State House
- South Carolina State Museum
- Columbia Museum of Art
- Colonial Life Arena
- West Columbia Riverwalk Park and Amphitheater
- Saluda Shoals Park
- Sesquicentennial State Park
- Dreher Island State Park
- Columbia Metropolitan Convention Center
- Edventure
- Riverfront Park
- Soda City Market
- Koger Center for the Arts
- Segra Park
- Lake Murray Dam North Recreational Area
- Frankie's Fun Park





