
Guest house holiday rentals in Lee County
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Lee County
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Lee County
Family-friendly guest house rentals

Perfect go away!

Tropical Guest Suite Escape

Luxury retreat- guest house

Pool House with Lanai & Deck

Attached Room, Cape Harbour area

Cozy Guest Suite with Private Entrance

Zen Yard with Cozy 1 Bedroom Private entrance apt

The Little Villa
Guest house rentals with a patio

Beachy Airstream Oasis with Bikes

Beachside Living – Walk to the Water!

Private Suite Pool Home

Serene Studio Steps from the Water

Sand shack retreat canal w/pool

Seabreeze Lodge

Villa Tortuga Apartment Near airport / Patio BBQ

Adorable & spacious efficiency w/ full kitchen
Guest house rentals with a washing machine and dryer

Adorable Cottage with Heated Pool -Jaccuzi - Sauna

The Palmview Loft

South Fort Myers close to FGCU and beaches

Summer Breeze 25-0009

Seahorse Studio

Country Bungalow Guest House

“Luxury Efficiency in San Carlos

Casa Del Franco
Destinations to explore
- Waterfront rentals Lee County
- Rentals with pools Lee County
- Cottage rentals Lee County
- Rentals with a patio Lee County
- Rentals with beach access Lee County
- Rentals with a washing machine and dryer Lee County
- Pet-friendly rentals Lee County
- Rentals with lake access Lee County
- Flat rentals Lee County
- Rentals with a kayak Lee County
- Rentals with outdoor seating Lee County
- Smoking-friendly rentals Lee County
- Apartment rentals Lee County
- Rentals with a firepit Lee County
- Rentals with a fireplace Lee County
- Rentals with breakfast Lee County
- House rentals Lee County
- Private suite rentals Lee County
- Villa rentals Lee County
- Rentals with an accessible-height toilet Lee County
- Beachfront rentals Lee County
- Ski-in/ski-out rentals Lee County
- Tiny house rentals Lee County
- Townhouse rentals Lee County
- Rentals with a hot tub Lee County
- Family-friendly rentals Lee County
- Fitness-friendly rentals Lee County
- Rentals with an EV charger Lee County
- Guest house rentals Florida
- Guest house rentals United States
- Cabins United States
- Treehouses United States
- Tiny Houses United States
- Beach Houses United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Naples Beach
- Captiva Island
- Caspersen Beach
- Manasota Key Beach
- Lovers Key Beach
- Barefoot beach Bonita Springs,FL
- Clam Pass Park
- The Club at The Strand
- Englewood Beach
- North Jetty Beach
- Seagate Beach Club
- Worthington Country Club
- Stump Pass Beach State Park
- South Jetty Beach
- Heritage Bay Golf & Country Club
- Panther Run Golf Club
- Spanish Wells Country Club
- LaPlaya Golf Club
- Gasparilla Island State Park
- Blind Pass Beach
- Bonita National Golf & Country Club
- Talis Park Golf Club
- Spring Run Golf Club
- Boca Grande Pass