
Holiday rentals in La Mesilla
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Top-rated holiday rentals in La Mesilla
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Sky-filled 'Studio Cielito' @ Rancho Los Sonadores
Welcome to Studio Cielito - a desert-inspired cottage designed with bath lovers in mind. Curated with vintage touches, luxury linens, and everything you need to relax and rejuvenate near the magical Sangre de Cristo Mountains. Just 8 mins from Meow Wolf and 14 mins from The Plaza, but surrounded by nature with a country feel. If your dates are not avail, click on our profile for our other rentals. **Due to COVID-19, we are asking that all guests be vaccinated to help keep our community safe.

Mountain View Retreat | Peaceful & Cozy Escape
Comfortably accommodates 2 guests. A 3rd guest may be considered upon request/prior approval. Wake up to breathtaking Sangre de Cristo Mountain views in this cozy 350 sqft private casita—perfect for couples or solo travelers seeking comfort, calm, and a peaceful getaway. Enjoy a bright, thoughtfully designed space with privacy, private entrance, and fully equipped kitchen. Sip coffee with mountain views and unwind in a peaceful setting guests love for its comfort, cleanliness, and atmosphere.

Desert Hideaway - Private Casita Suite
Brand new shower!! Experience the ultimate desert escape at our guest suite, nestled amidst majestic mountains. This charming oasis offers a serene retreat with a queen bed, full kitchen, bath, and dining room. Embrace the tranquility of the desert landscape as you relax in the cozy suite & savor panoramic mountain views. Immerse yourself in nature's beauty embarking on thrilling adventures. Discover the perfect balance between comfort & breathtaking surroundings in this idyllic desert haven.

Hilltop Nest
Kick back and relax in this stylish cabin in the forest. Hilltop location with forever views. Just off scenic Route 66 (Hwy 50), up a steep (but short) driveway, sits a 2-bedroom log cabin with plenty of birdsong and pine trees, a porch surrounded by views and furnished with a grill for outdoor dining. Five miles east is the village of Pecos with the Pecos River for fishing, hiking, and exploring. Sixteen miles north is the legendary city of Santa Fe packed with world-class art and culture

Hawk House
This cozy 2-story home sits on 10 acres in the Chama River Valley, with views of Cerro Pedernal and the mountains. Rustic, cozy, with all basic amenities. Ideal for the solo artist or couple. Hiking + hot springs nearby, including Ghost Ranch, Poshuouingue ruins & Ojo Caliente Springs! Most pets are welcome (for a pet fee). It's helpful to check in on it, however, due to our contained pups further back on the land. Open to longer stays at discounted price. Write about either to discuss!

Incredible Northern New Mexico Experience Awaits
Enjoy amazing vistas while you relax after a day hike, biking or rafting in the Rio Grande del Norte National Monument, or long day skiing. You'll love the memorable experience gained from this elegant adobe home. Prepare that savory dinner w/ amigos in the gourmet kitchen or enjoy a book during a soothing bath. The home kid friendly and centrally located w/ privacy you’ll cherish. Casa El Guiqueno provides the northern NM experience your looking for at a price that won’t break the bank.

Cozy Forest Escape with Private Hot Tub
Escape to a Peaceful Forest Retreat Nestled on a 1.5-acre wooded lot, this relaxing cabin offers the perfect retreat for nature lovers and adventure seekers. Located adjacent to the Valles Caldera National Preserve, our property boasts: - Relaxing Hot Tub: Unwind among the pines - Wildlife watching opportunities - Short drive to Fenton Lake for top-notch fishing - Modern comforts for a peaceful stay - Proximity to outdoor activities for all seasons: hiking, biking, fishing, and skiing

River Oasis | Hot Springs Nearby
Nestled at the base of a majestic mountain, Casa del Rio offers sweeping views of the mesa and river, with the Jemez River flowing right through the property. Modern amenities meet natural beauty—enjoy sunsets from the deck, s’mores by the riverside firepit, and drift off to the soothing sounds of the water. Just five minutes from hot springs and scenic hikes, and only an hour from Santa Fe or Albuquerque, it’s the perfect place to relax, explore, and make unforgettable memories.

Charming Camper near Santa Fe
Newly renovated modern & spacious camper is located on a private gated 3.5 acre property in historic and beautiful Española River Valley, surrounded by 200 year old cottonwood trees and a running acequia. Located only 27 miles from Santa Fe, 24 miles from Abiquiu, 43 miles from Taos, 21 miles from Los Alamos, 12 miles from Chimayo, and 90 miles from Albuquerque, this relaxing & well-equipped camper provides the perfect getaway and home-base for your stay in Northern New Mexico.

Beautiful View
Nambé, New Mexico in Santa Fe County quiet rural setting. It is located 20 minutes from Historic Santa Fe, surrounded by Ancient Anasazi hiking trails and ruins. On the High Road to Taos. Enjoy the peace of the country. Safe and friendly. Romantic, comfortable ,within a private compound. All the amenities of home. Star filled nights, quaint, beautiful accommodations and a charming shared garden to relax and enjoy the beauty of the view of the Sangre de Cristo Mountains.

Infinite Views | Ridgetop Retreat | 2 Hot Tubs
There's nothing quite like this in Santa Fe — a genuine Earthship eco-home on a secluded ridgetop, with two hot tubs and views that stretch to the Jemez Mountains. 🛁 2 hot tubs — indoor jetted spa with waterfall & rooftop infinity tub 🌄 Sweeping views of Santa Fe, the Jemez Mountains & National Forest 🌿 Rare Earthship design with living indoor gardens 🧘 Dedicated spa & yoga retreat 🏡 Spacious 2BR entire earth-home, secluded ridgetop setting

The Cabin - Tiny Home near Santa Fe & Los Alamos
Plan your vacation at this cute little cabin! The kitchen is furnished with a refrigerator/freezer, oven/stove, microwave, toaster, coffee pot and more. There is A/C and heating as well as a smart TV and Wifi so you can have a comfortable, relaxing, and productive stay! On top of all that, we are centrally located between Los Alamos, Santa Fe, Pojoaque and Taos so you can easily visit some of our most amazing tourist spots!
Popular amenities for La Mesilla holiday rentals
Other great holiday rentals in La Mesilla

High Moon Japanese Mountain Retreat

Casita in Nambe

Casa Chuparosa (The Hummingbird House)

Kokopelli Suite

Luxury Tesuque Retreat, Hot Tub, Kiva Fireplaces

Centrally Located Southwest Oasis-Sage Casita

Bishop's Lodge Retreat, Mountain Views, Fire Pit

Modern Dome Home near Santa Fe | Los Alamos | Taos
Destinations to explore
- Santa Fe Plaza
- Ski Santa Fe
- Meow Wolf
- Bandelier National Monument
- Sipapu Ski & Summer Resort
- Santa Fe Farmers Market
- Georgia O'Keeffe Museum
- Santa Fe National Forest
- Rio Grande Gorge Bridge
- Museum of International Folk Art
- Loretto Chapel
- The Cathedral Basilica Of St. Francis Of Assisi
- El Santuario De Chimayo
- Taos Plaza
- Pecos National Historical Park
- Hyde Memorial State Park
- Valles Caldera National Preserve
- Vivác Winery
- Bandelier National Monument





