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Holiday rentals in Isla Drake

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Isla Drake

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Two rustic-style cabins are set along the shoreline, surrounded by lush tropical trees. A wide patio is furnished with colorful chairs, offering views of the water. The natural beauty of the landscape is complemented by the tranquil waves gently lapping at the shore.
Home in La Guaira
4.97 out of 5 average rating, 114 reviews

Puntita Manzanillo, fantastic sea and jungle

Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Guest favourite
Flat in Panama City
4.93 out of 5 average rating, 155 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Top guest favourite
Place to stay in Panama City
5.0 out of 5 average rating, 17 reviews

Casa Condal - Your Luxury Retreat in Cerro Azul

Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Guest favourite
Serene waters reflect vibrant greens and blues, surrounded by lush vegetation. Two sailboats are anchored nearby a rustic hut, offering a glimpse of a tranquil lagoon. The distant hills cradle the scene, enhancing a connection with the natural landscape.
Home in Portobelo
5.0 out of 5 average rating, 15 reviews

AeolusGuestHouse Home in Portobelo National Park

Welcome to AeolusGuestHouse, a hidden retreat in Jose del Mar, inside the Portobelo National Park. Surrounded by protected jungle, mangroves, and calm lagoon. Ideal for disconnecting in nature. Kayaks are available, and boats pick you up at the dock in front of the house for local tours, including Venas Azules just 15 minutes away. The home offers 2 bedrooms, 4 beds, an equipped kitchen, AC, parking, and helpful hosts always ready to assist. Pure nature, zero crowds, unforgettable stays.

Superhost
An aerial view showcases a rustic cottage surrounded by lush palm trees, located near a sandy beach. The gentle waves of the ocean are visible, along with several red-roofed structures nestled within the greenery, creating a serene coastal atmosphere.
Cottage in Palenque
4.87 out of 5 average rating, 95 reviews

Beachfront House in Caribbean sandy beach

Enjoy this rustic and cozy cottage with its almost private beach surrounded by beautiful palm trees along the whole area. With 2 oceanview bedrooms, 2 full bathrooms and a third bedroom in a mezzanine. Has a patio with a built in uruguayan parrilla, ideal for BBQs. Step in beautiful white sand and bath in crystal clear water. Coconut breakfasts watching the sunrise become a routine in this paradise. - This is a rural setting. Not a 5 star hotel. Insects and small animals can be around.

Superhost
Home in Mechi
4.63 out of 5 average rating, 8 reviews

Beachfront Home | En-Suites + Chef & Tours Available

Wake up to the sound of the waves… More than a beachfront home, Zola Sol is a curated wellness and lifestyle experience, thoughtfully designed around you. Whether you’re looking to relax, reconnect, or celebrate, we can personalize your stay with experiences such as private chef, wellness services, juice offerings, boat tours, and more—all seamlessly arranged before or during your visit. Your Airbnb reservation is simply the first step in creating an unforgettable Zola Sol experience.

Superhost
Two comfortable chairs are positioned on a tiled patio, facing an open gazebo by the sea. The gazebo's blue roof contrasts with the natural surroundings, and sunlight reflects off the water, enhancing the serene setting.
Cottage in Portobelo
4.81 out of 5 average rating, 93 reviews

Nice house , in front of the beach.

Unique accommodation, with plenty of space for you to enjoy with your loved ones. It is a complete beach house, with two rooms, with air conditioning, a queen bed and three single beds. It has full kitchen, utensils and barbecue. Gazebo facing the sea with 2 hammocks also in the internal corridor of the house. Fiber optic WiFi that guarantees stability and high speed of navigation, smart TV with more than 19,000 channels. It has a patio, terraces, parking for 5 cars. We are Pet Friendly

Top guest favourite
An inviting infinity pool overlooks a stunning coastal view. A spacious seating area, featuring colorful cushions, complements the serene atmosphere. Natural light fills the space, enhancing the connection to the outdoors, while the blue waters of the pool blend seamlessly with the distant ocean.
Villa in Cacique
4.98 out of 5 average rating, 57 reviews

FACING THE SEA Cacique (Portobello Park)

A house! A real glass island in the heart of the jungle! In the middle of the Portobello National Park (access only by 4x4 AWD) nestled at the top of the hill, between sky/sea, away from all eyes, a transparent house where glass embraces nature on all sides creating a unique connection between the inside and the outside, ideal for resting, disconnecting, comfortable, spacious, cool (central air conditioning), exclusive. It is the witness of a grandiose spectacle that awaits you!

Guest favourite
A serene swimming pool is depicted surrounded by lush palm trees, with the tranquil sea visible in the background. The water's clear blue tiles reflect the sky and nearby greenery, while the gentle curvature of the pool edge invites relaxation.
Villa in Portobelo
4.97 out of 5 average rating, 87 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Superhost
Home in Isla Grande
5.0 out of 5 average rating, 4 reviews

Beachfront House + Kitchen + Balcony + AC + Wi-Fi @ Isla Grande

✔️Verified Superhost Your stay will be in the best hands! 🚨Send us a message with the word DISCOUNT and ask about special promotions 📍 Apartment in Isla Grande, Colón Province, Panama 🇵🇦 🏡 Clean, comfortable and safe space, great location 🧼 Equipped with supplies and cleaning supplies During your booking, your Airbnb has: 🌐Wi-Fi. 📺TV 🍳Kitchen Ocean 🌊front ❄️A/C 🚗Parking 👉Send us a message with the word DISCOUNT and ask for promotions

Guest favourite
Cabin in Panama City
4.93 out of 5 average rating, 90 reviews

The Crystal House: Luxury Modern Wood Cabin

Create unforgettable memories at this unique and family-friendly place. Stay in a cabin in the middle of Chagres National Park, 50 minutes from the city. You can be in contact with nature while having all the comforts of a luxury accommodation. With one of the best views of the city, you can enjoy a good barbecue, a nap in the hammock, or a meeting around the fireplace. Relax and connect with the beautiful green of Panama. We'll be waiting for you!

Guest favourite
Home in Gamboa
4.86 out of 5 average rating, 109 reviews

BirdHouse — Gamboa, Panama Canal Rainforest

BirdHouse: Let's inhabit the space. Designed for people who want to experience the tropics, not shut them out. Open the screens, feel the breeze, listen to the rain, cool off in the pool, and wake to birds and howler monkeys. Located in historic Gamboa, BirdHouse is a place to slow down and experience one of the world’s richest tropical forests from the comfort of a thoughtfully designed home.

Popular amenities for Isla Drake holiday rentals

  1. Airbnb
  2. Panama
  3. Isla Drake