
Holiday rentals in East Prairie
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in East Prairie
Guests agree: these stays are highly rated for location, cleanliness and more.

Dawns Retreat
No pets. Dawns Retreat is a farm house remodeled in 2023 with a rustic feel that offers a cozy relaxing stay. WiFi 3 smart tv’s 1 Queen 1 full Gas fireplace Gas grill Open fire grill Firewood Electricity at fire pit Plenty of parking Garage Deer hanging station. Heart of Shawnee National Forest. Golconda 10min. Eddyville 15min Harrisburg 35min Paducah KY 35min Note: the field around the yard is private property. Things to do in the area Horseback riding Hiking Boating Fishing Huntin

RIVER and SKY Treehouse -Hot tub-Amazing Views-
The River and Sky cabin offers a unique experience with floor to ceiling windows that brings the outdoors in overlooking the St. Francois River. The small cabin has everything you need for a weekend alone, a romantic getaway, or a relaxing time with friends. Sip your morning coffee overlooking the river. Create a rustic outdoor dining experience by cooking with the electric grill under the covered outdoor kitchen. Immerse yourself in the hot tub as eagles fly overhead, or stargaze at night.

The Cottage, Rusted Route Farms
You won’t forget your time in this romantic, memorable place. The Cottage at Rusted Route Farms is a 1 bedroom beautiful suite on an old 10 acre farm history galore. A picturesque pond is settled next to The Market our onsite Restaurant that will be serving food and drinks to be ready on your arrival or for a certain time that you choose. The over 125 year old barn has been renovated to keep the history alive and is located here on site. This retreat is located right outside Cape Girardeau.

Twisted Sassafras Treehouse
A custom-built treehouse located on 10 acres with a water view that you can take in from the hot tub on the deck! It is nestled high in the trees and is the perfect romantic getaway for two! Feel like you are away from it all without being away from it all! This treehouse is located on a county road just minutes from Cape Girardeau. Enjoy catch and release fishing on site, local wineries, shopping in historic downtown Cape Girardeau, local restaurants, gambling, historical sites & more!

Under the Stars - Farmhouse
Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

Modern Luxury Cabin, Fireplaces, Hot Tub Paducah
Shepherd’s Lantern Acres offers an unparalleled luxury retreat experience, featuring two cabins that seamlessly blend modern comfort with breathtaking natural beauty. Your cabin features unobstructed views of over 2 acres of seasonal wildflower meadows and pristine nature. Dogs are also welcome to enjoy their very own dog spa! With a beautiful master suite, well-appointed kitchen, and in unit laundry, we have ensured that all the comforts of home are at your fingertips.

Cypress Bend cabin w/hot tub on Black River
Cozy new built cabin on a bend of the beautiful Black River. You’ll walk up the 14 stairs to a large screened in covered deck with hot tub and sitting area, and gas grill. The glass doors and windows allow you views of the river. The theme throughout is Indian-Aztec. Accommodates only two adults. If you’re looking for a peaceful/romantic get away this is the perfect place. Located approximately 2 hours south of St. Louis, and less than 15 minutes from Poplar Bluff, MO.

Panthers Inn Treehouse
Come nestle amongst the leaves at Panthers Inn Treehouse. This secluded, well equipped, elevated cabin has the perfect combination of natural beauty and artful luxury. Isolated yet conveniently located 2 minutes from Blue Sky and Feather Hill wineries, within 5 minutes of Panthers Den hiking trail and the Shawnee Hills canopy tour and only 10 min from I-57 exit 40. Panthers Inn is the perfect starting and ending point to your Shawnee Hills Wine Country vacation!

Glamping Dome · Hot Tub, Fire Pit & Forest Views
One of Illinois' most-favorited Airbnb listings — and once you arrive, you'll understand why. Soak in your private hot tub under a canopy of stars, wake up to panoramic forest views through floor-to-ceiling dome windows, then explore 8 acres of total seclusion. King bed, full kitchen, washer/dryer, fire pit, and charcoal grill all included. Intentionally TV-free — the night sky is the entertainment. Minutes from Shawnee National Forest trails and wine country.

Family Home near the MS River with a toy Room
The whole group will enjoy easy access to everything from this centrally located place. 3 blocks from the New Madrid boat ramp / levee. Less than 5 miles from HWY 55. Large family style home - on the first level - living room, dining room, kitchen, laundry room, guest bathroom, main bedroom and main bathroom. The upstairs has 2 bedrooms and a toy room with another full bathroom upstairs.

The Peery House at Springhill Farms
The Peery House is our family home-place, built circa 1900, transformed into a quaint Airbnb. It is located on our farm, Springhill Family Farms in Western KY and is a great place for someone looking to get away from the busyness of life, looking for rest and relaxation or just looking for a unique, little farmhouse while passing through the area.

Large living space, 4 bedroom, outdoor fire pit
Spacious 4BR/2BA cabin in Wickliffe, KY—ideal for work crews, hunters, or families. Sleeps 8 with full kitchen, washer/dryer, and cozy living space. Plenty of parking for trucks and trailers. Quiet, rural setting close to Kentucky Lake, hunting, fishing, paper mill, river industry and KY/IL bridge project.
Popular amenities for East Prairie holiday rentals
Other great holiday rentals in East Prairie

Farmer Ty’s ranch house from ‘Farmer Wants a Wife’

The Brooks Estate

The Hideaway at Reelfoot Lake

Cozy Tiny House In The Country | Firepit |Sunsets

Welcome to The Fish Camp!

3 Bedroom 1 Bath Home in Portageville - Sleeps 7

Nana's Place

Crooked Creek Treehouses (Stony Branch Loft)
Destinations to explore
- Nashville Holiday rentals
- Indianapolis Holiday rentals
- St. Louis Holiday rentals
- Louisville Holiday rentals
- Memphis Holiday rentals
- Branson Holiday rentals
- Chattanooga Holiday rentals
- Birmingham Holiday rentals
- Hot Springs Holiday rentals
- Lexington Holiday rentals
- Bentonville Holiday rentals
- Eureka Springs Holiday rentals





