
Apartment holiday rentals in Downtown
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Top-rated apartment rentals in Downtown
Guests agree: these apartments are highly rated for location, cleanliness and more.

House of Blues - Medical Ctr/Rim/Six Flags
Beautiful 2 bedroom, 1 bath townhome nestled in a charming, established neighborhood filled with mature trees. Designed for comfort and style, this cozy retreat is perfect for relaxing and making memories. Centrally located, the Townhome is just 12 minutes from the Medical Ctr, 11 minutes from Fiesta Texas, 18 minutes from the River Walk, and 16 minutes from The Pearl. Close to major freeways, shopping centers, restaurants, and local attractions, making it the perfect home base for your SA stay.

2Bed Townhome Lackland, Medical Center, Six Flags
Welcome Home! Nestled in the corner of a quiet end-unit community. Cheaper than a hotel. Brand new everything to feel like home! 2 Memory foam beds, 1 King and 1 Queen. The sofa has memory foam Simmons queen mattress, and Comfy mypillows. 1 Full bathroom and 1 half bath with a full kitchen, washer, and dryer, fast High-Speed WiFI. Accommodate 6-8. Close to shopping areas, Medical Center, Seaworld, Fiesta, Six Flags, downtown(Riverwalk), and Lackland Airforce Base. Great for military graduations!

Howdy Holiday: Upscale Retreat Medical Center
Welcome to our Gated Modern-Upscale Medical Center Retreat with dedicated parking space! A luxury home, well furnished, vibrant, and an entertaining living room with opulent and cozy bedroom space, well-placed furniture, and living essentials. Centrally located near Six Flags Fiesta Texas, SeaWorld, Downtown & multiple shopping centers to include La Cantera shopping center, restaurants, Texas bar & grills, & much more. Wheelchair accessible, first floor with dedicated/reserved parking space.

Historic King William Gem •Walk to Dining & Coffee
Stay in the heart of the King William Historic District in this private upstairs residence. This highly walkable location is close to the River Walk, Convention Center, local restaurants, coffee shops, and more. Enjoy a thoughtfully curated retreat surrounded by San Antonio’s iconic historic homes and the quieter stretch of the River Walk path. Whether you’re visiting for a weekend getaway, business trip, or extended stay, this cozy space offers comfort, character, and an unbeatable location.

Med. Center Sleeps 6 Downstairs Apt #1
Perfect for LONG TERM STAYS, medical professionals, families & contract workers. Our Condo offers ample space & amenities to accommodate everyone in your group. It is nestled in a safe community, & located near major retail outlets & restaurants: 2 miles from Methodist Hosp, Va Hosp, UMC, UT Health, etc. 9 miles from SATX Airport 9 miles from 6 Flags 10 miles from Downtown 11 miles from SeaWorld 12 miles from LAFB For more information, see photos & read below. "Stay & Save Money ".

Magnolia Cottages 269
Huge Live Oaks trees surround this quiet relaxing community located in the Marymont neighborhood. This condo is luxuriously decorated, cozy, relaxing, comfortable, and quiet. This place is nice if you want a place to truly relax and enjoy. Granite counter tops throughout, new carpet, and tile. Large living area with flat screen TV, desk work area, nice dining area, full bath, private balcony with sitting area, large closet, washer and dryer inside. Queen size bed with luxurious linens.

Our Reviews Say It All~Exc Location/Well Appointed
Stay in the heart of it all ~ Located in the historic King William District! • Steps to several restaurants & bars • Just 2 blocks to the River Walk • Under 1 mile to the Convention Center, Alamodome, The Alamo, Tower of the Americas & Downtown • 5-minute walk to Bar Loretta, Little Em’s, Friendly Spot & several other eateries in Southtown • 10-minute walk to Blue Star Art District & Guenther House • 2 miles to The Pearl | 4 miles to AT&T Center • 15-minute drive to Lackland AFB

Urban Downtown condo. Alamodome and Convention ctr
Indulge in breathtaking skyline views from the expansive balcony that spans the entire length of this second-floor residence. Behind a charming historic facade, the interiors exude a sleek and modern ambiance, adorned with tasteful contemporary furnishings, elegant retro accents, and captivating feature walls. The stylish color scheme incorporates serene shades of teal and dusky pinks, harmoniously complementing a cool and sophisticated gray palette.

Riverfront Balcony 1BR · Pool · Gym · Parking
Wake up riverside! Step onto your private balcony, watch kayaks glide by, then stroll 18 min to the Alamo & downtown eats. Your perks in one place: - 24/7 infinity pool & gym - Free secure garage parking + EV charger - Pet-friendly; on-site dog park - Fast Wi-Fi & 75” smart TV After exploring Pearl District, unwind in the queen suite or cook in the fully stocked kitchen. Self-check-in, superhost support, unforgettable stay Book now!

Cozy 2BR Home near Med Center
Welcome to our cozy 2-bedroom townhome! Nestled in a quiet neighborhood in northwest San Antonio, our home offers the perfect blend of comfort and convenience. Just minutes away from the San Antonio Medical Center, our location is ideal for medical professionals, patients seeking respite, or travelers exploring this beautiful city. With nearly everything within a 20-minute drive, our townhome is your gateway to all of San Antonio.

Wyndham La Cascada Resort|1BR Balc Pool River Walk
This resort offers you the best of both worlds: more on-site amenities and unit choices than you'd find in most urban area resorts, plus a location convenient to the San Antonio River Walk. It's the ideal blend of resort-style fun and urban excitement. Wyndham La Cascada Resort|1BR Balc Pool River Walk Room Details • Size: 812 - 995 • Kitchen: Full • Baths: 1 • Accommodates: 4 Guests • Beds: King Bed - 1 Queen Sleeper Sofa - 1

Wyndham La Cascada Resort|3BR/3BA King Presidential Suite
This resort offers you the best of both worlds: more on-site amenities and unit choices than you'd find in most urban area resorts, plus a location convenient to the San Antonio River Walk. It's the ideal blend of resort-style fun and urban excitement. Wyndham La Cascada Resort|3BR/3BA King Pres Suite Room Details • Size: 1558 - 1558 • Kitchen: Full • Baths: 3 • Accommodates: 8 Guests • Beds: King Bed - 2 Queen Bed - 2
Popular amenities for Downtown apartment rentals
Weekly apartment rentals

Wyndham La Cascada Resort|3BR/3BA King Presidential Suite

Riverwalk + Pool View 1BR · Gym · Free Parking

Wyndham La Cascada Resort|2BR/2BA Riverwalk Suite

Wyndham La Cascada Resort|1BR Balc Pool River Walk

Med. Center Sleeps 5 Near 6 Flags/Sea World Apt #4

Riverfront King 1BR · Pool · Gym · Free Parking

Riverwalk View 1BR · Balcony · Pool · Parking

Wyndham Riverside Suites | King Bed Studio Suite
Pet-friendly apartment rentals

Fantastic condo with private bedroom and bathroom!

Private Apartment w/a beautiful patio!

The White House! Permit # STR-22-13500006

Condo Retreat Luxe Comforts

Beautiful apartment in a residential complex

Near Riverwalk, Hemisfair, Art & Dining Spots

Walk 2* Methodist Hospital Metropolitan*Pearl*Zoo*

Chic 2bd/1ba Home | Near Family Attractions
Apartment rentals with a pool

Club Wyndham La Cascada One-Bedroom Suite

2 Bedroom Deluxe Suite on Riverwalk

Unique & Affordable: Condo in the Heart of SATX!

La Cascada Resort, San Antonio TX / 2Bd Dlx Suite

Wyndham La Cascada Resort|1BR Balc Pool River Walk

Private Condominium

Private Bedroom & Bathroom Only – Quiet Condo Stay

1 BR/June Summer Week/San Antonio/Riverwalk
Quick stats about apartment rentals in Downtown

Total holiday rentals
Explore 170 holiday rentals in Downtown

Nightly prices starting at
Downtown holiday rentals start at €43 per night before taxes and fees

Verified guest reviews
Over 2,150 verified reviews to help you choose

Family-friendly holiday rentals
90 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 10 rentals that welcome pets

Holiday rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
60 properties have a dedicated workspace

Wifi availability
170 of Downtown holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Downtown rentals

4.7 Average rating
Downtown stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Downtown’s top spots include Alamodome, Tower of the Americas and San Antonio Museum of Art
Destinations to explore
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- Apartment rentals San Antonio
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- Apartment rentals United States
- San Antonio River Walk
- Six Flags Fiesta Texas
- Alamodome
- Henry B. Gonzalez Convention Center
- Frost Bank Center
- SeaWorld San Antonio
- Guadalupe River State Park
- Natural Bridge Caverns
- Blue Hole Regional Park
- Pearl Brewery
- Schlitterbahn Waterpark & Resort
- Morgan's Wonderland
- University of Texas at San Antonio
- Wimberley Market Days
- Blanco State Park
- Canyon Springs Golf Club
- Tower of the Americas
- San Antonio Missions National Historical Park
- San Antonio Botanical Garden
- The Alamo
- Government Canyon State Natural Area
- Natural Bridge Wildlife Ranch
- Jacob's Well Natural Area
- San Antonio Zoo & Aquarium





