Holiday rentals in Des Moines County

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Top-rated holiday rentals in Des Moines County

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
An open-concept living area features a modern kitchen with a large island and bar seating. A sleek stove and coffee maker are visible, while a flat-screen TV is mounted on the wall. Large windows allow ample natural light to fill the space, complementing the contemporary furnishings.
Flat in Burlington
4.98 out of 5 average rating, 45 reviews

Spacious New & Clean 2 BR Heart of Downtown! 301S

Step into this updated and spacious 2-bedroom, 2-bath retreat in the heart of downtown Burlington. Nestled in a newly built property, this modern rental is surrounded by some of the city’s best attractions. Savor a vibrant culinary scene with trendy new restaurants, sip your way through boutique wine shops, or treat yourself at nearby upscale hair salons. Perfectly located for convenience and relaxation, this urban oasis offers the ideal home base for exploring all Burlington has to offer!

Guest favourite
A well-lit hallway features a dining area with a wooden table and chairs. A comfortable armchair is positioned beside a soft ottoman on a textured rug. Natural light filters through windows adorned with light curtains, creating a welcoming atmosphere.
Home in Burlington
5 out of 5 average rating, 17 reviews

River Ridge Place

This unique place has a style all its own - a perfect balance of comfort and luxury! Tucked quietly just off of River and Harrison Avenue on a dead end street over looking the Mississippi River. This home offers a river view, three off street parking spaces, and a back deck for entertaining in the warmer months. Utilize your own in-house laundry room, Wi-Fi, and office space. Enjoy Downtown Burlington with only a quick 3 minute drive to some of the best shopping and dining experiences!

Top guest favourite
The exterior of a stately Victorian home is showcased, featuring a distinct tower and decorative trim. A covered porch with white railings invites relaxation. Lush green grass surrounds the property, complemented by a pebbled driveway and flowering planters near the entrance.
Home in Burlington
4.99 out of 5 average rating, 105 reviews

Miss Victoria- T.L. Porter House

This stately Victorian home overlooks the Mighty Mississippi River with stunning views of the Great River Bridge that connects Iowa and Illinois . Set on the historic South Bluff in Burlington, Miss Victoria is the place you want to be. This home is located in a peaceful and scenic neighborhood. With a large shared lot for pets and kids. Off street parking & garage. We are located 1.5 miles from downtown Burlington. Jefferson Street offers blocks of small business shops and restaurants.

Guest favourite
A vibrant mural featuring a peacock is displayed on a white wall, contrasting with the rustic brick backdrop. The neon sign reading 'The Peacock Loft' adds a modern touch, while a dark staircase leads upward, highlighted by industrial-style lighting.
Loft in Burlington
4.98 out of 5 average rating, 305 reviews

The Peacock Loft / Spacious Artistic Loft

A whimsical, art-filled retreat. Filled with treasured pieces from years of travel and free-spirited living, the loft is now a space for rest, inspiration, and slow mornings. Layered with color, photography, books, and meaningful objects, it’s perfect for guests who love creative, collected spaces. Please note: this is an older urban building with character, multiple stairs, no elevator, and some city noise. Fans, sound machines, blackout curtains, and earplugs are provided.

Top guest favourite
A living room features a leather sofa, two vintage armchairs, and a round ottoman, creating a cozy seating arrangement. Natural light enters through large windows framed with sheer curtains. Dark wooden flooring contrasts with the light-colored walls and decorative art pieces are displayed throughout.
Home in Burlington
4.9 out of 5 average rating, 246 reviews

The Fleetwood Bungalow with Dreamy Porch

Welcome to The Fleetwood Inn! A charming, cozy one-bedroom bungalow in the heart of Burlington, Iowa. Right between our bustling business district and our nostalgic downtown, this little house has vast character. My favorite feature is all the original built-ins and beams. You will love the Western American inspiration and vintage finds, modern touches throughout, and dreamy details in every corner. Just added a Saatva Organic mattress for extra comfort.

Top guest favourite
A cabin sits atop a gently sloping area covered with gravel, surrounded by green grass. A deck with black railings is visible at the front of the cabin, showcasing large windows that provide natural light to the interior.
Cabin in Oquawka
4.98 out of 5 average rating, 100 reviews

The Shoreline Shanty

Take it easy at this unique and tranquil getaway. This cabin offers a outstanding view overlooking the river. You will find you are very close to everything Oquawka has to offer, restaurants, bars, parks, laundry mat, grocery store, car wash, & churches. ( FOR THOSE OF YOU WHO ENJOY BOATING ON THE MISSISSIPPI RIVER ARE LOCAL BOAT CLUB OFFERS BOAT SLIPS FOR RENT AND FREE TRAILER PARKING DURING YOUR STAY, UPON BOOKING DETAILS WILL BE PROVIDED)

Top guest favourite
A serene view of the Mississippi River at sunset, featuring vibrant hues of purple, pink, and orange in the sky. A boat gently navigates the water, leaving a soft wake, while lush greenery frames the scene on the riverbank.
Townhouse in Burlington
4.97 out of 5 average rating, 66 reviews

Mosquito Park Condo

Have fun with the whole family at this stylish 1890 building. There's a park that overlooks the Mississippi. And for the musically inclined there is a piano. Play your heart out! And it's just a short walk downtown. Where there's lots of great restaurants and cool shops. Rates are set by AirBnB. I offer weekly and monthly stays discounts. If there are any more than two guests there will be an additional charge for the third to eighth guests.

Top guest favourite
A historic home is set back from a brick-paved street, surrounded by lush greenery. Two trees frame the entrance, where a charming porch is accessed by a pathway. A lamppost stands nearby, enhancing the inviting atmosphere of the area.
Home in Burlington
4.99 out of 5 average rating, 195 reviews

Snake Alley Inn, a one-of-a-kind location.

Snake Alley Inn, a Victorian home nestled high on the hill on Burlington's famous Snake Alley. This 1894 landmark brick-paved street, was once recognized by Ripley's Believe It or Not as the Crookedest Street in the World. Built in 1860 this historic home is adorned with 3 bedrooms and 2 full baths. Located within walking distance to Burlington's dynamic downtown, where you'll find many shops, pubs and eateries.

Guest favourite
A cozy living area is framed by two white columns, providing a view of a muted brown sectional sofa adorned with blue accent pillows. A coffee table sits in front of the sofa, with natural light filtering in through the large window dressed with dark curtains.
Townhouse in Burlington
4.96 out of 5 average rating, 102 reviews

Comfy Corner East

Welcome to Comfy Corner East in downtown Burlington, Iowa. Enjoy your stay in our 1880 duplex that overlooks downtown. You are just a walk over the bridge from all the shops and restaurants on Jefferson St. and another block north to Burlington’s infamous Snake Alley - the crookedest road in America. Conveniently located close to downtown entertainment and all the Mississippi river front has to offer.

Guest favourite
Home in Danville
5 out of 5 average rating, 7 reviews

The Cabin

Escape to your own private, one-of-a-kind getaway in the peaceful countryside of southeast Iowa. Perfectly located near Burlington, Mount Pleasant, Fort Madison, and just two miles from beautiful Geode State Park, this retreat offers the best of both worlds—close to local attractions yet far enough away to truly unwind. Enjoy a dip in our salt water pool. Pool hours are 8:00 AM to 10:00 PM.

Guest favourite
A well-lit open living space features two white armchairs with wooden frames and decorative cushions. A round pouf is positioned on a soft area rug. A dining table with black chairs is visible in the background, along with a doorway leading to additional rooms.
Home in Burlington
4.89 out of 5 average rating, 160 reviews

Haven on North Hill

Walking distance to historic downtown Burlington, Snake Alley and the mighty Mississippi River, Haven on North Hill is a lovingly renovated 1910 house. With an open floor plan, contemporary decor, natural light and two inviting porches, Haven on North Hill provides you with an ideal and charming space for slowing down, relaxing, and making wonderful memories with family and friends.

Top guest favourite
The exterior of the spacious home is showcased against a vibrant sunset, highlighting its modern design. The building features a combination of white and grey siding, large windows, and a covered porch area. A concrete driveway leads to the garages, surrounded by well-maintained greenery.
Home in Sperry
4.98 out of 5 average rating, 41 reviews

Porches and Pines Farmhouse

Room for All! With three fully furnished levels, Porches & Pines can comfortably sleep 16 guests. Our country farmhouse is located in rural Southeast Iowa and is the perfect place for a country retreat. Built on the edge of a Christmas tree farm, you will enjoy the peaceful environment of the 4 porches and the sound of the wind whispering through the pines.

Popular amenities for Des Moines County holiday rentals

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  2. United States
  3. Iowa
  4. Des Moines County