Holiday rentals in Depew

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Top-rated holiday rentals in Depew

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
The exterior of a two-story house is depicted, featuring grey siding and white trim. A well-maintained lawn surrounds the entrance, which is adorned with a seasonal wreath. Multiple large windows invite natural light, and landscaping includes shrubs and decorative stones.
Home in Lancaster
4.98 out of 5 average rating, 59 reviews

eye pleaser

Enjoy a stylish experience at this centrally-located home. Many guests come for the Buffalo Bills games. 25 minute ride to Highmark Stadium. 7 minutes from airport. 20 minutes to downtown Buffalo. Walking distance to the village of lancaster. The village offers restaurants, bars, shopping, coffee shop, barber shop etc. around the corner from the home offers a grocery store, liquor store, consumer beverages, and a gym. Enjoy our out door patio with grill, fire pit, as well as covered side patio.

Top guest favourite
The kitchen features modern stainless-steel appliances and a spacious wooden island with seating for three. Bright lighting enhances the clean lines of the white cabinetry and subway tile backsplash. Sliding glass doors provide access to the outdoor space, allowing natural light to fill the room.
Home in Cheektowaga
4.96 out of 5 average rating, 57 reviews

Serene, Renovated 2BR near Airport w/ Yard

Welcome to our bright and freshly renovated single-level home central to all in Buffalo, NY! This cozy home offers a serene and relaxing atmosphere, perfect for a short-term stay and loaded with amenities. Whether you're here for business or pleasure, our home provides all the comforts you need for a memorable stay. Book now and experience the best of Western New York! ** Mins from Buffalo Niagara Airport ** 1 mi to Walden Galleria Mall ** 9 mi to downtown Buffalo ** 10 mi to Highmark Stadium

Top guest favourite
The living room features a flat-screen television mounted on the wall, with a modern black entertainment center and a small side table. Natural light enters through a window adorned with light curtains, while a patterned rug and various furnishings add to the space.
Flat in Cheektowaga
5.0 out of 5 average rating, 38 reviews

Convenient cozy two bedroom apartment

Convenient newly furnished 2 bedroom apartment near Buffalo Airport, Centrally located near Buffalo and Niagara Falls. Close to University at Buffalo. Five minutes to Buffalo International Airport. Enjoy this private 2 bedroom apt. steps from a walking park & playground. Enjoy Buffalo cuisine from many local restaurants. Come cheer on the Bills or Sabres or attend one of the many festivals and music events Buffalo has to offer. The Galleria Mall is minutes away as well as supermarkets.

Top guest favourite
A single-story bungalow is showcased with a well-maintained lawn. The brick exterior is complemented by large windows that allow natural light. Neatly trimmed bushes and shrubs frame the entrance, while a pathway leads to the front door. A lamp post stands to the right, adding subtle illumination.
Home in Cheektowaga
4.94 out of 5 average rating, 105 reviews

Bungalow near BuffaloNiagara International Airport

Relax and unwind at this peaceful bungalow in suburban Buffalo. Comfortable 3-bedroom house located 2 miles from airport, 13.4 miles from Bills Stadium, 24 miles from Niagara Falls and only 15-minute drive from downtown Buffalo, NY. Two of the bedrooms are equipped with a queen-sized bed and the 3rd bedroom has a full sized bed. With plenty of storage space in the dressers and closets. Full kitchen/dining area. Laundry is available on site with a washer and dryer located in the basement.

Guest favourite
A living area features a wall-mounted television above a rustic wooden table. A small ladder shelf stands to the left, adorned with decorative items. The kitchen area is visible in the background, showcasing wooden cabinets and coffee-making equipment.
Flat in Depew
4.8 out of 5 average rating, 428 reviews

The Shecave - 2 Bedroom Apt

This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Superhost
A welcoming brick exterior of an upstairs apartment is shown, featuring a neatly manicured lawn. A small tree with white bark stands prominently in the front yard, surrounded by decorative stones. The entrance includes steps leading to a door with windows, reflecting natural light.
Flat in Cheektowaga
4.83 out of 5 average rating, 113 reviews

Upstairs apartment near the airport

Cozy & stylish upstairs apartment in a quiet suburb. Less than three miles from the airport for stress-free travel! Less than one mile from the Walden Galleria Mall, one of the largest in NY state! Less than 10 miles from downtown Buffalo rich in culture, history, art, GREAT food, and night life. 24 miles to Niagara Falls for beautiful hikes and sight seeing. A fun 2 hour road trip to Toronto! Clean & comfortable with everything you need for a short or long-term stay!

Superhost
A living area is shown with a light-colored sofa and a brown ottoman placed in front. A dark armchair with a patterned cushion adds contrast. A tall green plant is positioned beside a window, enhancing the natural light in the room. Neutral wall colors contribute to a calm atmosphere.
Flat in Depew
4.72 out of 5 average rating, 36 reviews

Clean + Efficient! Airport - 10 Min Downtown - 20

PLEASE READ ALL LISTING DETAILS Great for 1-2 people traveling for business or visiting family and friends. Centrally-located and just a few blocks from The Lancaster Village, this location has shops, restaurants and parks nearby - and is only 10 minutes to the airport and thruway access. NOTE: Apartment is accessible only by a sharply pitched staircase with narrow steps and limited foot space. Individuals with balance or mobility limitations may find them challenging.

Superhost
A living room area features a light-colored sofa set arranged around a circular glass-top table. A dark-patterned area rug is positioned beneath the furniture. A flat-screen television rests on a simple stand against the wall, while warm light emanates from a lamp on a side table.
Flat in Depew
4.83 out of 5 average rating, 24 reviews

Sharun’s Vacation House Near Niargafalls/Buffalo

Spacious 3-bedroom home in a prime location! Just 30 mins to Niagara Falls, 20 mins to Highmark Stadium, and within 5 mins walking distance to shops, restaurants, and all amenities. Perfect for families, groups, or long-term stays, this home offers a full kitchen, cozy living and dining areas, WiFi, smart TV, free parking, and a relaxing porch with outdoor space. Enjoy comfort and convenience while exploring all that Western New York has to offer.

Top guest favourite
A spacious balcony extends from the second floor, featuring two outdoor chairs and a small table. The view showcases a lush green lawn leading to the lake, framed by residential houses and trees under a clear blue sky.
Cottage in Fort Erie
4.96 out of 5 average rating, 152 reviews

Steps to the Beach + Lakeviews + HotTub + Elevator

Unwind at this The Red Lakehouse just steps from the beach, featuring a private hot tub, fire pit, and covered balcony with Lake Erie views. Perfect for families, groups, and getaways, this professionally designed home offers 3 bedrooms with private ensuites for ultimate comfort and privacy. Minutes to Niagara Falls, Crystal Beach, and the USA border — yet tucked in a quiet, relaxing neighbourhood. A spotless, thoughtfully curated stay.

Superhost
Flat in Bowmansville
4.74 out of 5 average rating, 161 reviews

Garden House Apartment

This lovely apartment has an open layout that includes a full kitchen and comfortable living space complete with a sofa-bed and large-screen TV . There is a private bedroom with a queen size bed. The decor is an eclectic collection of color, comfort and class. This decor was chosen with the intention that you, our guests will have a cozy experience when you choose The Garden House Apartment at Old Orchard Estate.

Top guest favourite
A charming exterior view showcases a white picket fence surrounding a well-kept yard. A lush green lawn is framed by flower beds, and a gazebo is visible in the background, complemented by mature trees providing shade.
Flat in Williamsville
4.95 out of 5 average rating, 166 reviews

Cozy Williamsville apartment at Madison Place

Cozy 1 bedroom 2nd floor apartment Eat in kitchen with countertop height seating 2 Queen size beds (bed & fold out couch) Brand new built in dishwasher & microwave oven All cookware, silverware & kitchen appliances Fully furnished with all linens, towels and starter supply of soaps, shampoos. Ample closet space and storage Whole house water filter Laundry located in basement Off street parking for 2 cars

Guest favourite
A modern living area features a dark sofa adorned with decorative cushions. A large television is mounted on a media console, while two abstract art pieces hang on the wall. Natural light enters through the nearby doorway, highlighting the warm wood flooring.
Flat in Depew
4.85 out of 5 average rating, 79 reviews

Modern 2-bedroom upper apartment with free parking

Enjoy a stay in our updated, modern apartment! This is the perfect place for professionals on business or for couples or families visiting the area. Conveniently located within 10 minutes of the Buffalo Airport and the Galleria Mall and within 20 minutes of KeyBank Center and Highmark Stadium. You're guaranteed a great stay in our cozy modern space! Apartment comfortably sleeps four.

Popular amenities for Depew holiday rentals

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